Topic summary

HERC2

HERC2
More reference expression dataBioGPSEnsemblUniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)Chr 15: 28.11 – 28.32 MbChr 7: 55.7 – 55.88 MbPubMed searchWikidata

HERC2, or HECT and RLD domain containing E3 ubiquitin protein ligase 2, is a giant E3 ubiquitin protein ligase, implicated in DNA repair regulation, pigmentation and neurological disorders. It is encoded by a gene of the same name belonging to the HERC family, which typically encodes large protein products with C-terminalHECT domains and one or more RCC1-like (RLD) domains.