Topic summary

GSK3A

GSK3A
More reference expression dataBioGPSEnsemblUniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)Chr 19: 42.23 – 42.24 MbChr 7: 24.93 – 24.94 MbPubMed searchWikidata

Glycogen synthase kinase-3 alpha is an enzyme that in humans is encoded by the GSK3Agene.

Glycogen synthase kinase 3-alpha EC2.7.1.37 is a multifunctional protein serine kinase, homologous to Drosophila 'shaggy' (zeste-white3) and implicated in the control of several regulatory proteins including glycogen synthase and various transcription factors (e.g., JUN). It also plays a role in the WNT and phosphoinositide 3-kinase (especially PIK3CG) signaling pathways.