Topic summary

CXCL9

CXCL9
More reference expression dataBioGPSEnsemblUniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)Chr 4: 76 – 76.01 MbChr 5: 92.47 – 92.48 MbPubMed searchWikidata

Chemokine (C-X-C motif) ligand 9 (CXCL9) is a small cytokine belonging to the CXC chemokine family that is also known as monokine induced by gamma interferon (MIG). CXCL9 is one of the chemokines that play a role chemotaxis induction, promote differentiation and multiplication of leukocytes, and cause tissue extravasation.

It is closely related to CXCL10 and CXCL11, whose genes are located near that of CXCL9 on human chromosome 4. CXCL9, CXCL10 and CXCL11 all elicit their chemotactic functions by interacting with the chemokine receptorCXCR3.