Topic summary

CDK9

Extracted from the Wikipedia article Cyclin-dependent kinase 9.

Function

CDK9 is also known to associate with other proteins such as TRAF2, and be involved in differentiation of skeletal muscle. In healthy cellular environments, the enzymatic activity of the resulting P-TEFb complex is tightly regulated and maintained in equilibrium via temporary sequestration by the 7SK snRNP negative regulatory complex.