Topic summary
Bird-flu
Extracted from the Wikipedia article Avian influenza.
References
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The influenza virus HA binds to alpha 2–3 linked (avian viruses) or alpha 2–6 linked (human viruses) sialic acids presented by proteins or lipids on the host cell surface.
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If an avian virus mutates or reassorts and gains the ability to bind to α2,6 linked sialic acids, it might cross the species barrier and infect humans. Swine tissues express both forms of sialic acid and can be coinfected with human and avian viruses. Thus, pigs serve as a melting vessel for human, avian and swine influenza strains.
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