Topic summary
Ambisense
Extracted from the Wikipedia article Sense (molecular biology).
Ambisense
A single-stranded genome that is used in both positive-sense and negative-sense capacities is said to be ambisense. Some viruses have ambisense genomes. Bunyaviruses have three single-stranded RNA (ssRNA) fragments, some of them containing both positive-sense and negative-sense sections; arenaviruses are also ssRNA viruses with an ambisense genome, as they have three fragments that are mainly negative-sense except for part of the 5′ ends of the large and small segments of their genome.