Alfaxalone

Chemical compound Pharmaceutical compound AlfaxaloneClinical dataTrade namesAlfaxanOther namesAlphaxalone; Alphaxolone; Alfaxolone; 3α-Hydroxy-5α-pregnane-11,20-dione; PHAX-001; Phaxan, Alphaxalone (BAN UK)AHFS/Drugs.comInternational Drug NamesLicense data US DailyMed: Alfaxan Drug class Neuroactive steroid General anesthetic ATCvet codeQN01AX05 (WHO) Legal statusLegal status AU: S4 (Prescription only) CA: ℞-only US: Schedule IV (by veterinarian only) Pharmacokinetic dataProtein binding30–50%MetabolismHepaticMetabolites Alfaxalone glucuronide (major in dogs) 20-Hydroxyalfaxalone sulfate (major in cats) Elimination half-life 25 min (dogs) 45 min (cats) ExcretionMostly renalIdentifiers IUPAC name (3R,5S,8S,9S,10S,13S,14S,17S)-17-acetyl-3-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-11-one CAS Number23930-19-0 YPubChem CID104845IUPHAR/BPS5461DrugBankDB11371 YChemSpider94637 YUNIIBD07M97B2AKEGGD07282 YChEMBLChEMBL190279 YCompTox Dashboard (EPA)DTXSID9022576 ECHA InfoCard100.164.405 Chemical and physical dataFormulaC21H32O3Molar mass332.484 g·mol−13D model (JSmol)Interactive image SMILES O=C2[C@H]3[C@H]([C@@H]1CC[C@H](C(=O)C)[C@