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Topic summary

Acetamide

Acetamide
Names Preferred IUPAC name
Acetamide
Systematic IUPAC name
Ethanamide
Other names
Acetic acid amide
Acetylamine
Identifiers
3D model (JSmol)
Abbreviations AcNH2ChEBI
ChEMBL
ChemSpider
DrugBank
ECHA InfoCard100.000.430EC Number
  • 200-473-5
KEGG
RTECS number
  • AB4025000
UNII
  • InChI=1S/C2H5NO/c1-2(3)4/h1H3,(H2,3,4)
    Key: DLFVBJFMPXGRIB-UHFFFAOYSA-N
  • InChI=1/C2H5NO/c1-2(3)4/h1H3,(H2,3,4)
    Key: DLFVBJFMPXGRIB-UHFFFAOYAC
  • O=C(N)C
Properties C2H5NOMolar mass59.068 g·mol Appearance colorless, hygroscopic solid Odorodorless
mouse-like with impurities Density1.159 g cm Melting point79 to 81 °C (174 to 178 °F; 352 to 354 K) Boiling point221.2 °C (430.2 °F; 494.3 K) (decomposes) 2000 g L Solubilityethanol 500 g L
pyridine 166.67 g L
soluble in chloroform, glycerol, benzenelog P−1.26 Vapor pressure1.3 Pa Acidity (pKa) 15.1 (25 °C, H2O) −0.577 × 10 cm g 1.4274 Viscosity2.052 cP (91 °C) Structure trigonal Thermochemistry 91.3 J·mol·K 115.0 J·mol·K −317.0 kJ·mol Hazards GHS labelling: WarningH351P201, P202, P281, P308+P313, P405, P501NFPA 704 (fire diamond)
3
1
1
Flash point126 °C (259 °F; 399 K) Lethal dose or concentration (LD, LC): 7000 mg kg (rat, oral) Safety data sheet (SDS) External MSDS
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Acetamide (systematic name: ethanamide) is an organic compound with the formula CH3CONH2. It is an amide derived from ammonia and acetic acid. It finds some use as a plasticizer and as an industrial solvent. The related compound N,N-dimethylacetamide (DMA) is more widely used, but it is not prepared from acetamide. Acetamide can be considered an intermediate between acetone, which has two methyl (CH3) groups either side of the carbonyl (CO), and urea which has two amide (NH2) groups in those locations. Acetamide is also a naturally occurring mineral with the IMAsymbol: Ace.

Wikipedia source