Topic summary
AVPR1A
Extracted from the Wikipedia article Vasopressin receptor 1A.
Mice
AVPR1A's role in social recognition is particularly important in the lateral septum, as using viral vectors to replace inactivated AVPR1A expression rescues social recognition and increases anxiety-related behavior. However, conflicting results have been found in another study. Also, unlike vasopressin 1b receptor and oxytocin knockout mice, AVPR1A knockout mice have a normal Bruce effect (appropriate failure of pregnancy in presence of novel male).