Topic summary
5-MeO-DET
5-MeO-DET, also known as 5-methoxy-N,N-diethyltryptamine is a psychedelic drug of the tryptamine family related to 5-MeO-DMT. It is taken orally but can also be used parenterally.
The drug produces strong side effects such as lightheadedness, dizziness, and vertigo at low doses that prevent hallucinogenic doses from being tolerated or used. It acts as a serotonin receptor modulator, including as an agonist of the serotonin5-HT2A receptor. 5-MeO-DET produces psychedelic-like effects in animals. Analogues of 5-MeO-DET include 5-MeO-DMT, 5-MeO-DPT, dipropyltryptamine (DPT), and 4-HO-DPT (deprocin), among others.
5-MeO-DET was first described in the literature by 1968. It was further described by Alexander Shulgin in his 1997 book TiHKAL (Tryptamines I Have Known and Loved). The drug was encountered as a novel designer drug in 2005.