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Pregnene

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A pregnene is an alkene derivative of a pregnane. An example is cortisone. ReferencesSee alsoPregnanes

PregnanePregnanePregnane, also known as 17β-ethylandrostane or as 10β,13β-dimethyl-17β-ethylgonane, is a C21 steroid and, indirectly, a parent of progesterone. It is a parent hydrocarbon for two series of steroids stemming from 5α-pregnane (originally allopregnane) and 5β-pregnane (17β-ethyletiocholane). It has a gonane core. 5β-Pregnane is the parent of pregnanediones, pregnanolones, and pregnanediols, and is found largely in urine as a metabolic product of 5β-pregnane compounds.CortisoneCortisoneCortisone is a naturally occurring, mostly inactive pregnene (21-carbon) steroid hormone. In the body, cortisone is produced as part of the cortisol–cortisone shunt, which protects vulnerable organs like the kidneys from cortisol. These organs produce the enzyme 11β-HSD2 which locally converts cortisol into inactive cortisone.AlkeneAlkeneIn organic chemistry, an alkene, or olefin, is a hydrocarbon containing one or more carbon–carbon double bonds. The double bond may be internal or at the terminal position. Terminal alkenes are also known as α-olefins.

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