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Polyamine

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Polyamines are a type of organic compound having two or more amino groups. The term is not defined consistently, but is typically used to refer to the naturally occurring putrescine, spermidine, and spermine, together with other related compounds. While some alkyl polyamines occur naturally, others are synthetic. Alkylpolyamines are colorless, hygroscopic, and water soluble. Near neutral pH, they exist as the ammonium derivatives. Most aromatic polyamines are crystalline solids at room temperature.

Ornithine decarboxylaseOrnithine decarboxylaseThe enzyme ornithine decarboxylase (EC4.1.1.17, ODC) catalyzes the decarboxylation of ornithine (a non-proteinogenic amino acid commonly produced from arginine) to form putrescine. Ornithine is part of both the urea cycle and polyamine synthesis, and this reaction is the committed step in that latter polyamine pathway. In the urea cycle, ornithine is instead acted on by the enzyme ornithine transcarbamylase. In humans, this protein has 461 amino acids and forms a homodimer.SpermidineSpermidineSpermidine is a polyamine compound (C7H19N3) originally isolated from semen and also found in ribosomes and living tissues and has various metabolic functions in organisms. FunctionSpermidine synchronizes an array of biological processes, (such as Ca, Na, K -ATPase) thus maintaining membrane potential and controlling intracellular pH and volume.DNADNADeoxyribonucleic acid (pronunciation; DNA) is a polymer composed of two polynucleotide chains that coil around each other to form a double helix. The polymer carries genetic instructions for the development, functioning, growth and reproduction of all known organisms and many viruses. DNA and ribonucleic acid (RNA) are nucleic acids.CadaverineCadaverineCadaverine is an organic compound with the formula (CH2)5(NH2)2. Classified as a diamine, it is a colorless liquid with an unpleasant odor. It is present in small quantities in living organisms but is often associated with the putrefaction of animal tissue. Together with putrescine, it is largely responsible for the foul odor of putrefying flesh, but also contributes to other unpleasant odors. ProductionCadaverine is produced by decarboxylation of lysine.PutrescinePutrescinePutrescine is an organic compound with the formula (CH2)4(NH2)2. It is a colorless solid that melts near room temperature. It is classified as a diamine. Together with cadaverine, it is largely responsible for the foul odor of putrefying flesh, but also contributes to other unpleasant odors. ProductionPutrescine is produced on an industrial scale by the hydrogenation of succinonitrile. Biotechnological production of putrescine from a renewable feedstock has been investigated.BrainBrainOrgan central to the nervous systemThe brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrateanimals. It consists of nervous tissue and is typically located in the head (cephalization), usually near organs for special senses such as vision, hearing, and olfaction.SpermineSpermine is a polyamine involved in cellular metabolism that is found in all eukaryotic cells. The precursor for synthesis of spermine is the amino acid ornithine. It is an essential growth factor in some bacteria as well. It is found as a polycation at physiological pH. Spermine is associated with nucleic acids and is thought to stabilize helical structure, particularly in viruses.MammalMammalA mammal (from Latin'breast') is a vertebrate animal of the classMammalia (). Mammals are characterized by the presence of milk-producing mammary glands for feeding their young, a broad neocortex region of the brain, fur or hair, and three middle ear bones. These characteristics distinguish them from reptiles and birds, from which their ancestors diverged in the Carboniferous period over 300 million years ago.Organic compoundOrganic compoundOrganic compounds are a subclass of chemical compounds of carbon. Little consensus exists among chemists on the exact definition of organic compound; the only universally accepted definition is the quasi-tautological "organic compounds are the subject matter of organic chemistry". Generally, any large chemical compound containing a carbon–hydrogen or carbon–carbon bond is accepted as an organic compound.Aromatic compoundAromatic compoundAromatic compounds or arenes are organic compounds "with a chemistry typified by benzene" and "cyclically conjugated." The word "aromatic" originates from the past grouping of molecules based on odor, before their general chemical properties were understood. The current definition of aromatic compounds does not have any relation to their odor. Aromatic compounds are now defined as cyclic compounds satisfying Hückel's rule.HygroscopyHygroscopy is the phenomenon of attracting and holding water molecules via either absorption or adsorption from the surrounding environment, which is usually at normal or room temperature. If water molecules become suspended among the substance's molecules, adsorbing substances can become physically changed, e.g. changing in volume, boiling point, viscosity or some other physical characteristic or property of the substance.AmineAmineIn chemistry, amines (, UK also ) are organic compounds that contain carbon–nitrogen bonds. Amines are formed when one or more hydrogen atoms in ammonia are replaced by alkyl or aryl groups. The nitrogen atom in an amine possesses a lone pair of electrons. Amines can also exist as heterocyclic compounds.

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