Antibody microarrayAn antibody microarray (also known as antibody array) is a specific form of protein microarray. In this technology, a collection of captured antibodies are spotted and fixed on a solid surface such as glass, plastic, membrane, or silicon chip, and the interaction between the antibody and its target antigen is detected. Antibody microarrays are often used for detecting protein expression from various biofluids including serum, plasma and cell or tissue lysates.
DNA microarrayA DNA microarray (also commonly known as a DNA chip or biochip) is a collection of microscopic DNA spots attached to a solid surface. Scientists use DNA microarrays to measure the expression levels of large numbers of genes simultaneously or to genotype multiple regions of a genome. Each DNA spot contains picomoles (10 moles) of a specific DNA sequence, known as probes (or reporters or oligos).
AffymetrixAmerican biotech company Affymetrix, Inc.TypeSubsidiaryIndustryBiotechnologyFounded1992HeadquartersSanta Clara, California, U.S.Number of locations11Key peopleStephen Fodor, Frank Witney (CEO)Revenue US$327 Million (FY 2009)Operating income US$-30.6 Million (FY 2009)Net income US$-23.9 Million (FY 2009)Total assets US$612 Million (FY 2009)Total equity US$288 Million (FY 2009)Number of employees1,141ParentThermo Fisher ScientificWebsitehttps://www.thermofisher.com/us/en/home/life-science/microarray-analysis.html Affymetrix is now Applied Biosystems, a brand of DNA microarray products sold by Thermo Fisher Scientific that originated with an American biotechnology research and development and manufacturing company of the same name.
Substrate (materials science)Substrate is a term used in materials science and engineering to describe the base material on which processing is conducted. Surfaces have different uses, including producing new film or layers of material and being a base to which another substance is bonded. DescriptionIn materials science and engineering, a substrate refers to a base material on which processing is conducted. This surface could be used to produce new film or layers of material such as depositedcoatings.
High-throughput screeningHigh-throughput screening (HTS) is a method for scientific discovery especially used in drug discovery and relevant to the fields of biology, materials science and chemistry. Using robotics, data processing/control software, liquid handling devices, and sensitive detectors, high-throughput screening allows a researcher to quickly conduct millions of chemical, genetic, or pharmacological tests.AssayAn assay is an investigative (analytic) procedure in laboratory medicine, mining, pharmacology, environmental biology and molecular biology for qualitatively assessing or quantitatively measuring the presence, amount, or functional activity of a target entity. The measured entity is often called the analyte, the measurand, or the target of the assay. The analyte can be a drug, biochemical substance, chemical element or compound, or cell in an organism or organic sample.Tse Wen ChangTse Wen Chang (Chinese: 張子文; pinyin: Zhāng Zǐwén, born August 25, 1947) is a Taiwanese immunologist. His early research involving the Immunoglobulin E (IgE) pathway and antibody-based therapeutics lead to the development of omalizumab (also known as Xolair), a medication that has been approved for the treatment of severe allergic asthma and severe chronic spontaneous urticaria.Multiplex (assay)In the biological sciences, a multiplex assay is a type of immunoassay that uses magnetic beads to simultaneously measure multiple analytes in a single experiment. A multiplex assay is a derivative of an ELISA using beads for binding the capture antibody. Multiplex assays are still more common in research than in clinical settings. In a multiplex assay, microspheres of designated colors are coated with antibodies of defined binding specificities.Biotic material(million years ago)Biotic material or biological derived material is any material that originates from living organisms. Most such materials contain carbon and are capable of decay. The earliest form of life on Earth arose at least 3.5 billion years ago.Lab-on-a-chipA lab-on-a-chip (LOC) is a device that integrates one or several laboratory functions on a single integrated circuit (commonly called a "chip") of only millimeters to a few square centimeters to achieve automation and high-throughput screening. LOCs can handle extremely small fluid volumes down to less than pico-liters. Lab-on-a-chip devices are a subset of microelectromechanical systems (MEMS) devices and sometimes called "micro total analysis systems" (μTAS).
Thin-film solar cellThin-film solar cells are a type of solar cell made by depositing thin layers of photovoltaic material onto a glass, plastic or metal substrate. Thin-film solar cells are typically much thinner than the wafers used in conventional crystalline silicon based solar cells. Thin-film solar cells are commercially made with one of several materials including cadmium telluride (CdTe), copper indium gallium diselenide (CIGS), and amorphous thin-film silicon (a-Si, TF-Si).
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