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Digoxin

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Digoxin, sold under the brand name Lanoxin, among others, is a medication used to treat various heart conditions. Most frequently it is used for atrial fibrillation, atrial flutter, and heart failure. Digoxin is one of the oldest medications used in the field of cardiology. It works by increasing myocardial contractility, increasing stroke volume and blood pressure, reducing heart rate, and somewhat extending the time frame of the contraction. Digoxin is taken by mouth or by injection into a vein.

Heart failureHeart failureFailure of the heart to provide sufficient blood flow throughout the bodyMedical conditionHeart failure (HF), also known as congestive heart failure (CHF), is a syndrome caused by an impairment in the heart's ability to fill with and pumpblood. Although symptoms vary based on which side of the heart is affected, HF typically presents with shortness of breath, excessive fatigue, and bilateral leg swelling.Atrial fibrillationAtrial fibrillationAtrial fibrillation (AF, AFib or A-fib) is an abnormal heart rhythm (arrhythmia) characterized by rapid and irregular beating of the atrial chambers of the heart. It often begins as short periods of abnormal beating, which become longer or continuous over time. It may also start as other forms of arrhythmia, such as atrial flutter, that transform into AF. Episodes can be asymptomatic.Atrial flutterAtrial flutterAtrial flutter (AFL) is a common abnormal heart rhythm that starts in the atrial chambers of the heart. When it first occurs, it is usually associated with a fast heart rate and is classified as a type of supraventricular tachycardia (SVT). Atrial flutter is characterized by a sudden-onset (usually) regular abnormal heart rhythm on an electrocardiogram (ECG) in which the heart rate is fast.Blood pressureBlood pressureBlood pressure (BP) is the pressure of circulating blood against the walls of blood vessels. Most of this pressure results from the heart pumping blood through the circulatory system. When used without qualification, the term "blood pressure" refers to the pressure in a brachial artery, where it is most commonly measured.Stroke volumeStroke volumeIn cardiovascular physiology, stroke volume (SV) is the volume of blood pumped from the ventricle per beat. Stroke volume is calculated using measurements of ventricle volumes from an echocardiogram and subtracting the volume of the blood in the ventricle at the end of a beat (called end-systolic volume) from the volume of blood just prior to the beat (called end-diastolic volume).Heart rateHeart rateHeart rate is the frequency of the heartbeat measured by the number of contractions of the heart per minute (beats per minute or bpm). The heart rate varies according to the body's physical needs, including the need to absorb oxygen and excrete carbon dioxide.Myocardial contractilityMyocardial contractility represents the innate ability of the heart muscle (cardiac muscle or myocardium) to contract. It is the maximum attainable value for the force of contraction of a given heart. The ability to produce changes in force during contraction result from incremental degrees of binding between different types of tissue, that is, between filaments of myosin (thick) and actin (thin) tissue.CardiologyCardiologyBranch of medicine dealing with the heartMedical specialtyCardiology (from Ancient Greek καρδίᾱ (kardiā) 'heart' and -λογία (-logia) 'study') is the study of the heart. Cardiology is a branch of medicine that deals with disorders of the heart and the cardiovascular system, and it is a sub-specialty of internal medicine.GynecomastiaGynecomastiaGynecomastia (also spelled gynaecomastia) is the non-cancerous enlargement of one or both breasts in men due to the growth of breast tissue as a result of a hormone imbalance between estrogens and androgens. Physically speaking, gynecomastia is completely benign, but it is associated with significant psychological distress, social stigma, and dysphoria.Muscle contractionMuscle contractionMuscle contraction is the activation of tension-generating sites within muscle cells. In physiology, muscle contraction does not necessarily mean muscle shortening because muscle tension can be produced without changes in muscle length (isometric contraction), such as when holding something heavy in the same position. The termination of muscle contraction is followed by muscle relaxation, which is a return of the muscle fibers to their low tension-generating state.Intravenous therapyIntravenous therapyIntravenous therapy (abbreviated as IV therapy) is a medical process that administers fluids, medications and nutrients directly into a person's vein. The intravenous route of administration is commonly used for rehydration or to provide nutrients for those who cannot, or will not—due to reduced mental states or otherwise—consume food or water by mouth.Cardiovascular diseaseCardiovascular diseaseCardiovascular disease (CVD) is any disease involving the heart or blood vessels. CVDs include coronary artery diseases (e.g. angina, heart attack), heart failure, hypertensive heart disease, valvular heart disease (e.g. rheumatic heart disease), cardiomyopathy, arrhythmia, congenital heart disease, carditis, aortic aneurysms, peripheral artery disease, thromboembolic disease, and venous thrombosis. The underlying mechanisms vary depending on the disease.digoxindigoxinRelated word or term.

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