Lassa virusLassa virus (LASV) is an arenavirus that causes Lassa hemorrhagic fever, a type of viral hemorrhagic fever (VHF), in humans and other primates. Lassa virus is an emerging virus and a select agent, requiring Biosafety Level 4-equivalent containment. It is endemic in West African countries, especially Sierra Leone, the Republic of Guinea, Nigeria, and Liberia, where the annual incidence of infection is between 300,000 and 500,000 cases, resulting in 5,000 deaths per year.
Viral hemorrhagic feverViral hemorrhagic fevers (VHFs) are a diverse group of infectious diseases characterized by fever and systemic damage to the circulatory system caused by RNA viruses. Viral hemorrhagic fevers cause symptoms ranging from mild to life-threatening, depending on the virus involved, but generally cause internal bleeding that leads to sudden onset of muscle pain, fever, and hypotension. In severe cases, it can cause life-threatening shock and bleeding from internal organs.
BunyaviricetesBunyaviricetes is a class of segmented negative-strand RNA viruses with mainly tripartite genomes. Member viruses infect arthropods, plants, protozoans, and vertebrates. The name Bunyaviricetes derives from Bunyamwera, where the virus Bunyamwera virus was first discovered. Bunyaviruses belong to the fifth group of the Baltimore classification system, which includes viruses with a negative-sense, single-stranded RNA genome. They have an enveloped, spherical virion.
Lujo virusLujo virus (Mammarenavirus lujoense) is a bisegmented RNA virus—a member of the family Arenaviridae—and a known cause of viral hemorrhagic fever (VHF) in humans.Inclusion body diseaseInclusion body disease (IBD) is an infectious and invariably fatal viral disease affecting captive specimens of the boid family of snakes, particularly Boa constrictor. It has been recognized since the mid-1970s. It is so named because of the characteristic intracytoplasmic inclusion bodies that are observed in clinical examinations in epidermal cells, oral mucosal epithelial cells, visceral epithelial cells, and neurons.
Lassa feverLassa fever, also known as Lassa hemorrhagic fever, is a type of viral hemorrhagic fever caused by the Lassa virus. Many of those infected by the virus do not develop symptoms. When symptoms occur, they typically include fever, weakness, headaches, vomiting, and muscle pains. Less commonly there may be bleeding from the mouth or gastrointestinal tract. The risk of death once infected is about one percent and frequently occurs within two weeks of the onset of symptoms.Whitewater Arroyo virusWhitewater Arroyo virus (WWAV) is a zoonotic Arenavirus associated with hemorrhagic fever with liver failure.
Lymphocytic choriomeningitisLymphocytic choriomeningitis (LCM) is a rodent-borne viral infectious disease that presents as aseptic meningitis, encephalitis or meningoencephalitis. Its causative agent is lymphocytic choriomeningitis virus (LCMV), a member of the family Arenaviridae. The name was coined by Charles Armstrong in 1934. Lymphocytic choriomeningitis is "a viral infection of the membranes surrounding the brain and spinal cord and of the cerebrospinal fluid".
RobovirusA rodent-borne virus, abbreviated as robovirus, is a zoonotic virus that is transmitted by a rodent vector. Roboviruses mainly belong to the virus families Arenaviridae and Hantaviridae. Like arbovirus (arthropod borne) and tibovirus (tick borne) the name refers to its method of transmission, known as its vector. This is distinguished from a clade, which groups around a common ancestor.
Venezuelan hemorrhagic feverVenezuelan hemorrhagic fever (VHF) is a zoonotic human illness first identified in 1989. The disease is most prevalent in several rural areas of central Venezuela and is caused by Guanarito virus (GTOV) which belongs to the Arenaviridae family. The short-tailed cane mouse (Zygodontomys brevicauda) is the main host for GTOV which is spread mostly by inhalation of aerosolized droplets of saliva, respiratory secretions, urine, or blood from infected rodents.Brazilian hemorrhagic feverBrazilian hemorrhagic fever (BzHF) is an infectious disease caused by Sabiá virus, an arenavirus. Sabiá virus is one of the arenaviruses from South America to cause hemorrhagic fever. It shares a common progenitor with Junín virus, Machupo virus, , and Guanarito virus. It is an envelopedRNA virus and is highly infectious and lethal. Very little is known about this disease, but it is thought to be transmitted by the excreta of rodents.Bolivian hemorrhagic feverBolivian hemorrhagic fever (BHF), also known as black typhus or Ordog Fever, is a hemorrhagic fever and zoonotic infectious disease endemic to Bolivia after infection by Machupo virus (MACV). The virus is spread primarily by the large vesper mouse (Calomys callosus). BHF was first recognized in 1959 during the first reported outbreak near the city of San Joaquin in the Beni district of northeast Bolivia. Symptoms include fever, malaise, bleeding, and in some cases, death.*As an Amazon Associate I earn from qualifying purchases.