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Allotransplantation

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Allotransplant (allo- meaning "other" in Greek) is the transplantation of cells, tissues, or organs to a recipient from a genetically non-identical donor of the same species. The transplant is called an allograft, allogeneic transplant, or homograft. Most human tissue and organ transplants are allografts.

Transplant rejectionTransplant rejectionTransplant rejection occurs when transplanted tissue is rejected by the recipient's immune system, which destroys the transplanted tissue. Transplant rejection can be lessened by determining the molecular similitude between donor and recipient and by use of immunosuppressant drugs after transplant.XenotransplantationXenotransplantationTransplantation of cells or tissue across speciesMedical interventionXenotransplantation (xenos- from the Greek meaning "foreign" or strange), or heterologous transplant, is the transplantation of living cells, tissues or organs from one species to another. Such cells, tissues or organs are called xenografts or xenotransplants.Transplantation (medicine)Transplantation (medicine)Transplantation is a medical procedure in which an organ, tissue, or cells are removed from one organism and placed in a recipient organism, often to replace a damaged or missing function. The donor and recipient may be at the same location, or organs may be transported from a donor site to another location. Organs and tissues that are transplanted within the same person's body are called autografts.AutotransplantationAutotransplantationAutotransplantation or autologous transplantation is the surgicaltransplantation of organs, tissues or even particular proteins from one site in an individual's body to another site within the same person ( meaning "self" in Greek). The autologous tissue (also called autogenous, autogeneic, or autogenic tissue) transplanted by such a procedure is called an autograft or autotransplant.Graft-versus-host diseaseGraft-versus-host diseaseGraft-versus-host disease (GvHD) is a syndrome, characterized by inflammation in different organs. GvHD is commonly associated with bone marrow transplants and stem cell transplants. White blood cells of the donor's immune system, which remain within the donated tissue (the graft), recognize the recipient (the host) as foreign (non-self). The white blood cells present in the transplanted tissue then attack the recipient's body cells, which leads to GvHD.SyngenicThe word "syngenic" or "syngeneic" (from the Greek word for a relative) means genetically identical, or sufficiently identical and immunologically compatible as to allow for transplantation. For example, it may be used for something transplanted from an identical twin. When the cells are collected from the same patient on whom they will be used, a graft is called autologous. Syngeneic refers to a graft transferred between genetically identical animals or people.IsograftIsograftAn Isograft is a graft of tissue between two individuals who are genetically identical (i.e. monozygotic twins). Transplant rejection between two such individuals virtually never occurs, making isografts particularly relevant to organ transplantations; patients with organs from their identical twins are incredibly likely to receive the organs favorably and survive.CartilageCartilageCartilage is a resilient and smooth type of connective tissue. Semi-transparent and non-porous, it is usually covered by a tough and fibrous membrane called perichondrium. In tetrapods, it covers and protects the ends of long bones at the joints as articular cartilage, and is a structural component of many body parts including the rib cage, the neck and the bronchial tubes, and the intervertebral discs.Cell (biology)Cell (biology)Basic unit of life formsThe cell is the basic structural and functional unit of all forms of life or organisms. The term comes from the Latin word cellula meaning 'small room'. A biological cell basically consists of a semipermeablecell membrane enclosing cytoplasm that contains genetic material. Most cells are only visible under a microscope.Ancient GreekAncient GreekAncient Greek (Ἑλληνική, Hellēnikḗ [hellɛːnikɛ̌ː]) includes the forms of the Greek language used in ancient Greece and the ancient world from around 1500 BC to 300 BC. It is often roughly divided into the following periods: Mycenaean Greek (c. 1400 – c. 1200 BC), Dark Ages (c. 1200 – c. 800 BC), the Archaic or Homeric period (c. 800 – c. 500 BC), and the Classical period (c. 500 – c. 300 BC).Tissue (biology)Tissue (biology)In biology, tissue is an assembly of similar cells and their extracellular matrix from the same embryonic origin that together carry out a specific function. Tissues occupy a biological organizational level between cells and a complete organ. Accordingly, organs are formed by the functional grouping of multiple tissues. The English word "tissue" derives from the French word "tissu", meaning "fabric", derived from the verb “tisser”, "to weave".Organ (biology)Organ (biology)In a multicellular organism, an organ is a collection of tissues joined in a structural unit to serve a common function. In the hierarchy of life, an organ lies between tissue and an organ system. Tissues are formed from same type cells to act together in a function. Tissues of different types combine to form an organ which has a specific function. The intestinal wall, for example, is formed by epithelial tissue and smooth muscle tissue.

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