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Alizarin

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Alizarin (also known as 1,2-dihydroxyanthraquinone, Mordant Red 11, C.I.58000, and Turkey Red) is an organic compound with formula C14H8O4 that has been used throughout history as a red dye, principally for dyeing textile fabrics. Historically it was derived from the roots of plants of the madder genus. In 1869, it became the first natural dye to be produced synthetically. Alizarin is the main ingredient for the manufacture of the madder lake pigments known to painters as rose madder and alizarin crimson.

Lake pigmentLake pigmentA lake pigment is a pigment made by precipitating a dye with an inertbinder, or mordant, usually a metallic salt. Lake pigments are largely chemically organic. Manufacturers and suppliers to artists and industry frequently omit the lake designation in the name. Many lake pigments are fugitive because the dyes involved are not lightfast.Alizarin crimson (color)Alizarin crimson (color)Alizarin crimson is a deep red color with a blue undertone. It is named after the organic dye alizarin, found in the madder plant, and the related synthetic lake pigment alizarin crimson (PR83 in the Color Index).Rose madderRose madderRose madder (also known as madder) is a red paint made from the pigment madder lake, a traditional lake pigment extracted from the common madder plant Rubia tinctorum. Madder lake contains two organic red dyes: alizarin and purpurin. As a paint, it has been described as a fugitive, transparent, nonstaining, mid valued, moderately dull violet red pigment in tints and medium solutions, darkening to an impermanent, dull magenta red in masstone.Organic compoundOrganic compoundOrganic compounds are a subclass of chemical compounds of carbon. Little consensus exists among chemists on the exact definition of organic compound; the only universally accepted definition is the quasi-tautological "organic compounds are the subject matter of organic chemistry". Generally, any large chemical compound containing a carbon–hydrogen or carbon–carbon bond is accepted as an organic compound.StainingStainingStaining is a technique used to enhance contrast in samples, generally at the microscopic level. Stains and dyes are frequently used in histology (microscopic study of biological tissues), in cytology (microscopic study of cells), and in the medical fields of histopathology, hematology, and cytopathology that focus on the study and diagnoses of diseases at the microscopic level.DyeDyeDyes made at De Kat, ZaandamA dye is a colored substance that is soluble in some solvent; by contrast pigments are insoluble or nearly so in all solvents. Because of their solubility, dyes can chemically bind to the material they color. Dye is generally applied in an aqueous solution and may require a mordant to improve the fastness of the dye on the fiber.CalciumCalciumChemical element with atomic number 20 (Ca)Mg↑Ca↓Srpotassium ← calcium → scandiumColour Index InternationalColour Index InternationalColour Index™ International (CI) is a reference database jointly maintained by SDC Enterprises and the American Association of Textile Chemists and Colorists. It currently contains over 27,000 individual products listed under 13,000 Colour Index™ Generic Names. It was first printed in 1924 but is now published solely on the Internet.CYP1A1CYP1A1More reference expression dataBioGPSEnsemblUniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)Chr 15: 74.72 – 74.73 MbChr 9: 57.6 – 57.61 MbPubMed searchWikidataCytochrome P450, family 1, subfamily A, polypeptide 1 is a protein that in humans is encoded by the CYP1A1gene. The protein is a member of the cytochrome P450 superfamily of enzymes.CYP1A2CYP1A2More reference expression dataBioGPSEnsemblUniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)Chr 15: 74.75 – 74.76 MbChr 9: 57.58 – 57.59 MbPubMed searchWikidataCytochrome P450 1A2 (abbreviated CYP1A2), a member of the cytochrome P450 mixed-function oxidase system, is involved in the metabolism of xenobiotics in the human body. In humans, the CYP1A2 enzyme is encoded by the CYP1A2gene. FunctionCYP1A2 is a member of the cytochrome P450 superfamily of enzymes.RubiaRubiaRubia is the type genus of the Rubiaceaefamily of flowering plants, which also contains Coffea (coffee). It contains around 80 species of perennial scrambling or climbing herbs and subshrubs native to the Old World. The genus and its best-known species are commonly known as madder, e.g. Rubia tinctorum (common madder), Rubia peregrina (wild madder), and Rubia cordifolia (Indian madder).CYP1B1CYP1B1More reference expression dataBioGPSEnsemblUniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)Chr 2: 38.07 – 38.11 MbChr 17: 80.01 – 80.02 MbPubMed searchWikidataCytochrome P450 1B1 is an enzyme that in humans is encoded by the CYP1B1gene. FunctionCYP1B1 belongs to the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids.

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