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Sir Stanford Cade (formerly Kadinsky), (22 March 1895 – 19 September 1973) was a British surgeon of Russian origin, who pioneered the combined use of surgery and
radiotherapy Radiation therapy or radiotherapy (RT, RTx, or XRT) is a treatment using ionizing radiation, generally provided as part of cancer therapy to either kill or control the growth of malignant cells. It is normally delivered by a linear particle ...
in the treatment of
cancer Cancer is a group of diseases involving Cell growth#Disorders, abnormal cell growth with the potential to Invasion (cancer), invade or Metastasis, spread to other parts of the body. These contrast with benign tumors, which do not spread. Po ...
in
England England is a Countries of the United Kingdom, country that is part of the United Kingdom. It is located on the island of Great Britain, of which it covers about 62%, and List of islands of England, more than 100 smaller adjacent islands. It ...
. He was born in what was then the
Russian Empire The Russian Empire was an empire that spanned most of northern Eurasia from its establishment in November 1721 until the proclamation of the Russian Republic in September 1917. At its height in the late 19th century, it covered about , roughl ...
, educated in
Antwerp Antwerp (; ; ) is a City status in Belgium, city and a Municipalities of Belgium, municipality in the Flemish Region of Belgium. It is the capital and largest city of Antwerp Province, and the third-largest city in Belgium by area at , after ...
, and started his medical training in
Brussels Brussels, officially the Brussels-Capital Region, (All text and all but one graphic show the English name as Brussels-Capital Region.) is a Communities, regions and language areas of Belgium#Regions, region of Belgium comprising #Municipalit ...
. His training was interrupted by the
First World War World War I or the First World War (28 July 1914 – 11 November 1918), also known as the Great War, was a World war, global conflict between two coalitions: the Allies of World War I, Allies (or Entente) and the Central Powers. Fighting to ...
, and he was evacuated to England. Cade's medical education continued at Westminster Hospital Medical School, and following qualification he did various jobs at
Westminster Hospital Westminster Hospital was a hospital in London, England, founded in 1719. In 1834 a medical school attached to the hospital was formally founded. In 1939 a newly built hospital and medical school opened in Horseferry Road, Westminster. In 1994 the ...
, finally being appointed consultant surgeon. He pioneered the combined use of
radium Radium is a chemical element; it has chemical symbol, symbol Ra and atomic number 88. It is the sixth element in alkaline earth metal, group 2 of the periodic table, also known as the alkaline earth metals. Pure radium is silvery-white, ...
or X rays in the treatment of cancer. During the
Second World War World War II or the Second World War (1 September 1939 – 2 September 1945) was a World war, global conflict between two coalitions: the Allies of World War II, Allies and the Axis powers. World War II by country, Nearly all of the wo ...
, Cade was a member of the
Royal Air Force Volunteer Reserve The Royal Air Force Volunteer Reserve (RAFVR) was established in 1936 to support the preparedness of the U.K. Royal Air Force (RAF) in the event of another war. The Air Ministry intended it to form a supplement to the Royal Auxiliary Air Force ( ...
. In addition to his medical work, he also advised on improvements in the design of the cockpits of fighter planes, for which he was awarded a knighthood. After the war, Cade's work led to him gaining several honours and appointments. Cade wrote two books on the treatment of cancer.


Early life and training

Stanford Cade, the son of a diamond merchant, was born in Dwinsk, then in the
Russian Empire The Russian Empire was an empire that spanned most of northern Eurasia from its establishment in November 1721 until the proclamation of the Russian Republic in September 1917. At its height in the late 19th century, it covered about , roughl ...
, now in
Latvia Latvia, officially the Republic of Latvia, is a country in the Baltic region of Northern Europe. It is one of the three Baltic states, along with Estonia to the north and Lithuania to the south. It borders Russia to the east and Belarus to t ...
. His family moved to St Petersburg, but at the age of eight he and his older brother were sent to school in
Antwerp Antwerp (; ; ) is a City status in Belgium, city and a Municipalities of Belgium, municipality in the Flemish Region of Belgium. It is the capital and largest city of Antwerp Province, and the third-largest city in Belgium by area at , after ...
. In 1913 Cade commenced his medical studies at the University of Brussels. When the First World War started two years later he volunteered to serve in the Belgian Army, but when Antwerp was overrun he was evacuated to England. Cade could speak Russian, French, and German, but no English, and he was allowed to write his first medical examination, which he passed, in French. He went to
King's College, London King's College London (informally King's or KCL) is a public university, public research university in London, England. King's was established by royal charter in 1829 under the patronage of George IV of the United Kingdom, King George IV ...
, and then won a scholarship to Westminster Hospital Medical School. Cade soon became fluent in speaking English, qualified as a doctor in 1917, and undertook a series of medical appointments at
Westminster Hospital Westminster Hospital was a hospital in London, England, founded in 1719. In 1834 a medical school attached to the hospital was formally founded. In 1939 a newly built hospital and medical school opened in Horseferry Road, Westminster. In 1994 the ...
. During this time, he became a British subject, and changed his surname from Kadinsky to Cade. He was appointed consultant surgeon at Westminster Hospital in 1924, and later became surgeon to the Radium Institute and to
Mount Vernon Hospital Mount Vernon Hospital is a hospital located in Northwood, London, Northwood in the London Borough of Hillingdon. It is one of two hospitals run by The Hillingdon Hospitals NHS Foundation Trust, the other being Hillingdon Hospital. History ...
. Cade became a
Fellow of the Royal College of Surgeons Fellowship of the Royal Colleges of Surgeons (FRCS) is a professional certification, professional qualification to practise as a senior surgeon in Republic of Ireland, Ireland or the United Kingdom. It is bestowed on an wikt:intercollegiate, ...
in 1923, Fellow of the Royal College of Obstetricians and Gynaecologists in 1954, and
Fellow of the Royal College of Physicians The Royal College of Physicians of London, commonly referred to simply as the Royal College of Physicians (RCP), is a British professional membership body dedicated to improving the practice of medicine, chiefly through the accreditation of ph ...
in 1961.


Career

At an early stage in his career, Cade took an interest in
regional anaesthesia Local anesthesia is any technique to induce the absence of sensation in a specific part of the body, generally for the aim of inducing local analgesia, i.e. local insensitivity to pain, although other local senses may be affected as well. It all ...
, and in 1925 his first Hunterian lecture was given on this subject. Following visits to the Radium Institute in Paris, he was influenced by the pioneering work of Claudius Regaud in the treatment of cancer by radiotherapy. Cade developed the therapeutic use of radium and X rays, combining this with surgery, and became an expert in these techniques. Together with other colleagues, he opened the Radium Annex of Westminster Hospital in
Hampstead Hampstead () is an area in London, England, which lies northwest of Charing Cross, located mainly in the London Borough of Camden, with a small part in the London Borough of Barnet. It borders Highgate and Golders Green to the north, Belsiz ...
. In line with his multidisciplinary approach to cancer treatment, Cade conducted combined clinics with radiotherapists. During the Second World War he became a member of the
Royal Air Force Volunteer Reserve The Royal Air Force Volunteer Reserve (RAFVR) was established in 1936 to support the preparedness of the U.K. Royal Air Force (RAF) in the event of another war. The Air Ministry intended it to form a supplement to the Royal Auxiliary Air Force ( ...
, eventually achieving the rank of
air vice marshal Air vice-marshal (Air Vce Mshl or AVM) is an air officer rank used by some air forces, with origins from the Royal Air Force. The rank is also used by the air forces of many Commonwealth of Nations, countries which have historical British infl ...
. During his service Cade's activities were not confined to surgery; he took an interest in the cause of injury to pilots, suggesting changes to the design of fighter planes cockpits. These were accepted and resulted in a reduction of casualties. For this work he was appointed a
Companion of the Order of the Bath Companion may refer to: Relationships Currently * Any of several interpersonal relationships such as friend or acquaintance * A domestic partner, akin to a spouse * Sober companion, an addiction treatment coach * Companion (caregiving), a caregi ...
, and at the end of the war he was awarded a knighthood as a
Knight Commander of the Order of the British Empire The Most Excellent Order of the British Empire is a British order of chivalry, rewarding valuable service in a wide range of useful activities. It comprises five classes of awards across both civil and military divisions, the most senior two o ...
, and was appointed as an
honorary air commodore Air commodore (Air Cdre or Air Cmde) is an air officer rank used by some air forces, with origins from the Royal Air Force. The rank is also used by the air forces of many Commonwealth of Nations, countries which have historical British influ ...
. Following the war Cade worked with the army and was appointed its honorary civilian consultant in radiotherapy. He was a member of the council of the
Royal College of Surgeons The Royal College of Surgeons is an ancient college (a form of corporation) established in England to regulate the activity of surgeons. Derivative organisations survive in many present and former members of the Commonwealth. These organisations ...
, later becoming its vice-president, a member of its court of examiners, and was awarded its Guthrie Medal. Cade's work was recognised worldwide; he was given honorary memberships and gave lectures in countries including the US, Chile, France, Ireland, and Greece.


Personal life

In 1920 Cade married Margaret Hester Agate, from Paisley, Scotland, who was a nurse at Westminster Hospital. She died from
malaria Malaria is a Mosquito-borne disease, mosquito-borne infectious disease that affects vertebrates and ''Anopheles'' mosquitoes. Human malaria causes Signs and symptoms, symptoms that typically include fever, Fatigue (medical), fatigue, vomitin ...
in 1951 in South Africa when they were visiting the country together. They had three daughters, one of whom became a radiotherapist.


Publications


Hunterian lectures

*1925 Regional anaesthesia *1933 The radiation treatment of cancer of the mouth and pharynx *1954 Adrenalectomy


Books

*1929 ''The Radium Treatment of Cancer'' *1940 ''Malignant Disease and its Treatment by Radium''


Notes


References


Further reading

* {{DEFAULTSORT:Cade, Stanford 1895 births 1973 deaths Alumni of King's College London Alumni of Westminster Hospital Medical School Belgian Army personnel Belgian Army personnel of World War I British oncologists Companions of the Order of the Bath English surgeons Fellows of the Royal College of Physicians Emigrants from the Russian Empire to the United Kingdom Honorary air commodores Knights Commander of the Order of the British Empire Naturalised citizens of the United Kingdom People from Daugavpils Royal Air Force air marshals of World War II Royal Air Force Volunteer Reserve personnel of World War II Emigrants from the Russian Empire to Belgium 20th-century British surgeons