The Seleucid Empire (; grc, Βασιλεία τῶν Σελευκιδῶν, ''Basileía tōn Seleukidōn'') was a
Greek
Greek may refer to:
Greece
Anything of, from, or related to Greece, a country in Southern Europe:
*Greeks, an ethnic group.
*Greek language, a branch of the Indo-European language family.
**Proto-Greek language, the assumed last common ancestor ...
state in
West Asia
Western Asia, West Asia, or Southwest Asia, is the westernmost subregion of the larger geographical region of Asia, as defined by some academics, UN bodies and other institutions. It is almost entirely a part of the Middle East, and includes A ...
that existed during the
Hellenistic period
In Classical antiquity, the Hellenistic period covers the time in Mediterranean history after Classical Greece, between the death of Alexander the Great in 323 BC and the emergence of the Roman Empire, as signified by the Battle of Actium in ...
from 312 BC to 63 BC. The Seleucid Empire was founded by the
Macedonian
Macedonian most often refers to someone or something from or related to Macedonia.
Macedonian(s) may specifically refer to:
People Modern
* Macedonians (ethnic group), a nation and a South Slavic ethnic group primarily associated with North M ...
general
Seleucus I Nicator
Seleucus I Nicator (; ; grc-gre, Σέλευκος Νικάτωρ , ) was a Macedonian Greek general who was an officer and successor ( ''diadochus'') of Alexander the Great. Seleucus was the founder of the eponymous Seleucid Empire. In the po ...
, following the
division of the
Macedonian Empire originally founded by
Alexander the Great
Alexander III of Macedon ( grc, Ἀλέξανδρος, Alexandros; 20/21 July 356 BC – 10/11 June 323 BC), commonly known as Alexander the Great, was a king of the ancient Greek kingdom of Macedon. He succeeded his father Philip II to ...
.
After receiving the
Mesopotamia
Mesopotamia ''Mesopotamíā''; ar, بِلَاد ٱلرَّافِدَيْن or ; syc, ܐܪܡ ܢܗܪ̈ܝܢ, or , ) is a historical region of Western Asia situated within the Tigris–Euphrates river system, in the northern part of the F ...
n region of
Babylonia
Babylonia (; Akkadian: , ''māt Akkadī'') was an ancient Akkadian-speaking state and cultural area based in the city of Babylon in central-southern Mesopotamia (present-day Iraq and parts of Syria). It emerged as an Amorite-ruled state ...
in 321 BC, Seleucus I began expanding his dominions to include the
Near Eastern territories that encompass modern-day
Iraq
Iraq,; ku, عێراق, translit=Êraq officially the Republic of Iraq, '; ku, کۆماری عێراق, translit=Komarî Êraq is a country in Western Asia. It is bordered by Turkey to Iraq–Turkey border, the north, Iran to Iran–Iraq ...
,
Iran
Iran, officially the Islamic Republic of Iran, and also called Persia, is a country located in Western Asia. It is bordered by Iraq and Turkey to the west, by Azerbaijan and Armenia to the northwest, by the Caspian Sea and Turkm ...
,
Afghanistan
Afghanistan, officially the Islamic Emirate of Afghanistan,; prs, امارت اسلامی افغانستان is a landlocked country located at the crossroads of Central Asia and South Asia. Referred to as the Heart of Asia, it is bord ...
,
Syria, all of which had been under Macedonian control after the fall of the former
Persia
Iran, officially the Islamic Republic of Iran, and also called Persia, is a country located in Western Asia. It is bordered by Iraq and Turkey to the west, by Azerbaijan and Armenia to the northwest, by the Caspian Sea and Turkme ...
n
Achaemenid Empire
The Achaemenid Empire or Achaemenian Empire (; peo, 𐎧𐏁𐏂, , ), also called the First Persian Empire, was an ancient Iranian empire founded by Cyrus the Great in 550 BC. Based in Western Asia, it was contemporarily the largest em ...
. At the Seleucid Empire's height, it had consisted of territory that had covered
Anatolia
Anatolia, tr, Anadolu Yarımadası), and the Anatolian plateau, also known as Asia Minor, is a large peninsula in Western Asia and the westernmost protrusion of the Asian continent. It constitutes the major part of modern-day Turkey. The r ...
,
Persia
Iran, officially the Islamic Republic of Iran, and also called Persia, is a country located in Western Asia. It is bordered by Iraq and Turkey to the west, by Azerbaijan and Armenia to the northwest, by the Caspian Sea and Turkme ...
, the
Levant
The Levant () is an approximation, approximate historical geography, historical geographical term referring to a large area in the Eastern Mediterranean region of Western Asia. In its narrowest sense, which is in use today in archaeology an ...
, and what are now modern
Iraq
Iraq,; ku, عێراق, translit=Êraq officially the Republic of Iraq, '; ku, کۆماری عێراق, translit=Komarî Êraq is a country in Western Asia. It is bordered by Turkey to Iraq–Turkey border, the north, Iran to Iran–Iraq ...
,
Kuwait
Kuwait (; ar, الكويت ', or ), officially the State of Kuwait ( ar, دولة الكويت '), is a country in Western Asia. It is situated in the northern edge of Eastern Arabia at the tip of the Persian Gulf, bordering Iraq to the no ...
,
Afghanistan
Afghanistan, officially the Islamic Emirate of Afghanistan,; prs, امارت اسلامی افغانستان is a landlocked country located at the crossroads of Central Asia and South Asia. Referred to as the Heart of Asia, it is bord ...
, and parts of
Turkmenistan
Turkmenistan ( or ; tk, Türkmenistan / Түркменистан, ) is a country located in Central Asia, bordered by Kazakhstan to the northwest, Uzbekistan to the north, east and northeast, Afghanistan to the southeast, Iran to the s ...
.
The Seleucid Empire was a major center of
Hellenistic culture.
Greek
Greek may refer to:
Greece
Anything of, from, or related to Greece, a country in Southern Europe:
*Greeks, an ethnic group.
*Greek language, a branch of the Indo-European language family.
**Proto-Greek language, the assumed last common ancestor ...
customs and language were privileged; the wide variety of local traditions had been generally tolerated, while an urban Greek elite had formed the dominant political class and was reinforced by steady immigration from
Greece
Greece,, or , romanized: ', officially the Hellenic Republic, is a country in Southeast Europe. It is situated on the southern tip of the Balkans, and is located at the crossroads of Europe, Asia, and Africa. Greece shares land borders wit ...
.
[Britannica,'' Seleucid kingdom'', 2008, O.Ed.] The empire's western territories
were repeatedly contested with
Ptolemaic Egypt—a rival Hellenistic state. To the east, conflict with the
Indian ruler
Chandragupta of the
Maurya Empire in 305 BC led to the
cession of vast territory west of the Indus and a political alliance.
In the early second century BC,
Antiochus III the Great attempted to
project Seleucid power and authority into
Hellenistic Greece
Hellenistic Greece is the historical period of the country following Classical Greece, between the death of Alexander the Great in 323 BC and the annexation of the classical Greek Achaean League heartlands by the Roman Republic. This culminated ...
, but his attempts
were thwarted by the
Roman Republic
The Roman Republic ( la, Res publica Romana ) was a form of government of Rome and the era of the classical Roman civilization when it was run through public representation of the Roman people. Beginning with the overthrow of the Roman Kingd ...
and its Greek allies. The Seleucids were forced to pay costly
war reparations
War reparations are compensation payments made after a war by one side to the other. They are intended to cover damage or injury inflicted during a war.
History
Making one party pay a war indemnity is a common practice with a long history.
...
and had to relinquish territorial claims west of the
Taurus Mountains
The Taurus Mountains (Turkish language, Turkish: ''Toros Dağları'' or ''Toroslar'') are a mountain range, mountain complex in southern Turkey, separating the Mediterranean Region, Turkey, Mediterranean coastal region from the central Anatolia# ...
in southern
Anatolia
Anatolia, tr, Anadolu Yarımadası), and the Anatolian plateau, also known as Asia Minor, is a large peninsula in Western Asia and the westernmost protrusion of the Asian continent. It constitutes the major part of modern-day Turkey. The r ...
, marking the gradual decline of their empire.
Mithridates I of Parthia conquered much of the remaining eastern lands of the Seleucid Empire in the mid-second century BC, while the independent
Greco-Bactrian Kingdom
The Bactrian Kingdom, known to historians as the Greco-Bactrian Kingdom or simply Greco-Bactria, was a Hellenistic-era Greek state, and along with the Indo-Greek Kingdom, the easternmost part of the Hellenistic world in Central Asia and the Ind ...
continued to flourish in the northeast.
The Seleucid kings were thereafter reduced to a
rump state in Syria, until their conquest by
Tigranes the Great of
Armenia
Armenia (), , group=pron officially the Republic of Armenia,, is a landlocked country in the Armenian Highlands of Western Asia.The UNbr>classification of world regions places Armenia in Western Asia; the CIA World Factbook , , and ...
in 83 BC, and ultimate overthrow by the Roman general
Pompey
Gnaeus Pompeius Magnus (; 29 September 106 BC – 28 September 48 BC), known in English as Pompey or Pompey the Great, was a leading Roman general and statesman. He played a significant role in the transformation of ...
in 63 BC.
Name
Contemporary sources, such as a loyalist decree honoring Antiochus I from
Ilium
Ilium or Ileum may refer to:
Places and jurisdictions
* Ilion (Asia Minor), former name of Troy
* Ilium (Epirus), an ancient city in Epirus, Greece
* Ilium, ancient name of Cestria (Epirus), an ancient city in Epirus, Greece
* Ilium Building, a ...
, in Greek language define the Seleucid state both as an empire (''arche'') and as a kingdom (''basileia''). Similarly, Seleucid rulers were described as kings in Babylonia.
Starting from the 2nd century BC, ancient writers referred to the Seleucid ruler as the
King of Syria,
Lord of Asia, and other designations; the evidence for the Seleucid rulers representing themselves as kings of Syria is provided by the inscription of
Antigonus son of Menophilus, who described himself as the "admiral of Alexander, king of Syria". He refers to either
Alexander Balas
Alexander I Theopator Euergetes, surnamed Balas ( grc, Ἀλέξανδρος Βάλας, Alexandros Balas), was the ruler of the Seleucid Empire from 150/Summer 152 – August 145 BC. Picked from obscurity and supported by the neighboring Roman ...
or
Alexander II Zabinas
Alexander II Theos Epiphanes Nikephoros ( grc, Ἀλέξανδρος Θεός Ἐπιφανής Νικηφόρος ''Áléxandros Theós Épiphanḗs Nikēphóros'', surnamed Zabinas; 150 BC – 123 BC) was a Hellenistic Seleucid monarch who ...
as a ruler.
History
Partition of Alexander's empire
Alexander, who quickly conquered the
Persian Empire under its last Achaemenid dynast,
Darius III
Darius III ( peo, 𐎭𐎠𐎼𐎹𐎺𐎢𐏁 ; grc-gre, Δαρεῖος ; c. 380 – 330 BC) was the last Achaemenid King of Kings of Persia, reigning from 336 BC to his death in 330 BC.
Contrary to his predecessor Artaxerxes IV Arses, Dar ...
, died young in 323 BC, leaving an expansive empire of partly Hellenised culture without an adult heir. The empire was put under the authority of a regent,
Perdiccas, and the vast territories were divided among Alexander's generals, who thereby became
satrap
A satrap () was a governor of the provinces of the ancient Median and Achaemenid Empires and in several of their successors, such as in the Sasanian Empire and the Hellenistic empires.
The satrap served as viceroy to the king, though with cons ...
s at the
Partition of Babylon
The Partition of Babylon was the first of the conferences and ensuing agreements that divided the territories of Alexander the Great. It was held at Babylon in June 323 BC.
Alexander’s death at the age of 32 had left an empire that stretched fro ...
, all in that same year.
Rise of Seleucus
Alexander's generals, known as ''
diadochi
The Diadochi (; singular: Diadochus; from grc-gre, Διάδοχοι, Diádochoi, Successors, ) were the rival generals, families, and friends of Alexander the Great who fought for control over his empire after his death in 323 BC. The Wa ...
'', jostled for supremacy over parts of his empire following his death.
Ptolemy I Soter
Ptolemy I Soter (; gr, Πτολεμαῖος Σωτήρ, ''Ptolemaîos Sōtḗr'' "Ptolemy the Savior"; c. 367 BC – January 282 BC) was a Macedonian Greek general, historian and companion of Alexander the Great from the Kingdom of Macedon ...
, a former general and then current satrap of
Egypt
Egypt ( ar, مصر , ), officially the Arab Republic of Egypt, is a transcontinental country spanning the northeast corner of Africa and southwest corner of Asia via a land bridge formed by the Sinai Peninsula. It is bordered by the Med ...
, was the first to challenge the new system, which eventually led to the demise of Perdiccas. Ptolemy's revolt created a new subdivision of the empire with the
Partition of Triparadisus in 320 BC.
Seleucus
Seleucus may refer to:
Monarchs and other people related to the Seleucid Empire
* Seleucus I Nicator (Satrap 311–305 BC, King 305 BC–281 BC), son of Antiochus and founder of the Seleucid Empire
* Seleucus II Callinicus (246–225 BC)
* Sele ...
, who had been "Commander-in-Chief of the
Companion cavalry" (''hetairoi'') and appointed first or court
chiliarch (which made him the senior officer in the Royal Army after the regent and commander-in-chief Perdiccas since 323 BC, though he helped to assassinate him later) received
Babylonia
Babylonia (; Akkadian: , ''māt Akkadī'') was an ancient Akkadian-speaking state and cultural area based in the city of Babylon in central-southern Mesopotamia (present-day Iraq and parts of Syria). It emerged as an Amorite-ruled state ...
and, from that point, continued to expand his dominions ruthlessly. Seleucus established himself in
Babylon in 312 BC, the year later used as the
foundation date of the Seleucid Empire.
Babylonian War (311–309 BC)
The rise of Seleucus in Babylon threatened the eastern extent of the territory of
Antigonus I Monophthalmus
Antigonus I Monophthalmus ( grc-gre, Ἀντίγονος Μονόφθαλμος , 'the One-Eyed'; 382 – 301 BC), son of Philip from Elimeia, was a Macedonian Greek nobleman, general, satrap, and king. During the first half of his life he ser ...
in Asia. Antigonus, along with his son
Demetrius I Poliorcetes, unsuccessfully led a campaign to annex Babylon. The victory of Seleucus ensured his claim of Babylon and legitimacy. He ruled not only Babylonia, but the entire enormous eastern part of Alexander's empire, as described by the historian
Appian
Appian of Alexandria (; grc-gre, Ἀππιανὸς Ἀλεξανδρεύς ''Appianòs Alexandreús''; la, Appianus Alexandrinus; ) was a Ancient Greeks, Greek historian with Ancient Rome, Roman citizenship who flourished during the reigns of ...
:
Seleucid–Mauryan War (305–303 BC)
Chandragupta Maurya
Chandragupta Maurya (350-295 BCE) was a ruler in Ancient India who expanded a geographically-extensive kingdom based in Magadha and founded the Maurya dynasty. He reigned from 320 BCE to 298 BCE. The Maurya kingdom expanded to become an emp ...
(
Sandrokottos) founded the
Maurya Empire in 321 BC after the
conquest of the
Nanda Empire and their capital
Pataliputra
Pataliputra ( IAST: ), adjacent to modern-day Patna, was a city in ancient India, originally built by Magadha ruler Ajatashatru in 490 BCE as a small fort () near the Ganges river.. Udayin laid the foundation of the city of Pataliputra at ...
in
Magadha. Chandragupta then redirected his attention to the Indus and by 317 BC he conquered the remaining Greek satraps left by Alexander. Expecting a confrontation, Seleucus gathered his army and marched to the Indus. It is said that Chandragupta could have fielded a
conscript
Conscription (also called the draft in the United States) is the state-mandated enlistment of people in a national service, mainly a military service. Conscription dates back to antiquity and it continues in some countries to the present day u ...
army of 600,000 men and 9,000 war elephants.
Mainstream scholarship asserts that Chandragupta received, formalized through a treaty, vast territory west of the Indus, including the
Hindu Kush, modern day
Afghanistan
Afghanistan, officially the Islamic Emirate of Afghanistan,; prs, امارت اسلامی افغانستان is a landlocked country located at the crossroads of Central Asia and South Asia. Referred to as the Heart of Asia, it is bord ...
, and the
Balochistan province of
Pakistan
Pakistan ( ur, ), officially the Islamic Republic of Pakistan ( ur, , label=none), is a country in South Asia. It is the world's List of countries and dependencies by population, fifth-most populous country, with a population of almost 24 ...
. Archaeologically, concrete indications of Mauryan rule, such as the inscriptions of the
Edicts of Ashoka, are known as far as
Kandahar
Kandahar (; Kandahār, , Qandahār) is a city in Afghanistan, located in the south of the country on the Arghandab River, at an elevation of . It is Afghanistan's second largest city after Kabul, with a population of about 614,118. It is the ca ...
in southern Afghanistan. According to Appian:

It is generally thought that Chandragupta married
Seleucus's daughter, or a
Macedonian
Macedonian most often refers to someone or something from or related to Macedonia.
Macedonian(s) may specifically refer to:
People Modern
* Macedonians (ethnic group), a nation and a South Slavic ethnic group primarily associated with North M ...
princess, a gift from Seleucus to formalize an alliance. In a return gesture, Chandragupta sent 500
war elephant
A war elephant was an elephant that was trained and guided by humans for combat. The war elephant's main use was to charge the enemy, break their ranks and instill terror and fear. Elephantry is a term for specific military units using elepha ...
s, a military asset which would play a decisive role at the
Battle of Ipsus
The Battle of Ipsus ( grc, Ἱψός) was fought between some of the Diadochi (the successors of Alexander the Great) in 301 BC near the town of Ipsus in Phrygia. Antigonus I Monophthalmus, the Macedonian ruler of large parts of Asia, and his ...
in 301 BC. In addition to this treaty, Seleucus dispatched an ambassador,
Megasthenes, to Chandragupta, and later
Deimakos to his son
Bindusara, at the Mauryan court at
Pataliputra
Pataliputra ( IAST: ), adjacent to modern-day Patna, was a city in ancient India, originally built by Magadha ruler Ajatashatru in 490 BCE as a small fort () near the Ganges river.. Udayin laid the foundation of the city of Pataliputra at ...
(modern
Patna
Patna (
), historically known as Pataliputra, is the capital and largest city of the state of Bihar in India. According to the United Nations, as of 2018, Patna had a population of 2.35 million, making it the 19th largest city in India. ...
in
Bihar state). Megasthenes wrote detailed descriptions of India and Chandragupta's reign, which have been partly preserved to us through
Diodorus Siculus
Diodorus Siculus, or Diodorus of Sicily ( grc-gre, Διόδωρος ; 1st century BC), was an ancient Greek historian. He is known for writing the monumental universal history '' Bibliotheca historica'', in forty books, fifteen of which ...
. Later
Ptolemy II Philadelphus
; egy, Userkanaenre Meryamun Clayton (2006) p. 208
, predecessor = Ptolemy I
, successor = Ptolemy III
, horus = ''ḥwnw-ḳni'Khunuqeni''The brave youth
, nebty = ''wr-pḥtj'Urpekhti''Great of strength
, golde ...
, the ruler of
Ptolemaic Egypt and contemporary of
Ashoka the Great, is also recorded by
Pliny the Elder
Gaius Plinius Secundus (AD 23/2479), called Pliny the Elder (), was a Roman author, naturalist and natural philosopher, and naval and army commander of the early Roman Empire, and a friend of the emperor Vespasian. He wrote the encyclopedic ...
as having sent an ambassador named
Dionysius to the Mauryan court.
Other territories ceded before Seleucus' death were
Gedrosia in the south-east of the Iranian plateau, and, to the north of this,
Arachosia on the west bank of the
Indus River.
Westward expansion

Following his and
Lysimachus' decisive victory over Antigonus at the
Battle of Ipsus
The Battle of Ipsus ( grc, Ἱψός) was fought between some of the Diadochi (the successors of Alexander the Great) in 301 BC near the town of Ipsus in Phrygia. Antigonus I Monophthalmus, the Macedonian ruler of large parts of Asia, and his ...
in 301 BC, Seleucus took control over eastern
Anatolia
Anatolia, tr, Anadolu Yarımadası), and the Anatolian plateau, also known as Asia Minor, is a large peninsula in Western Asia and the westernmost protrusion of the Asian continent. It constitutes the major part of modern-day Turkey. The r ...
and northern
Syria.
In the latter area, he founded a new capital at
Antioch on the Orontes
Antioch on the Orontes (; grc-gre, Ἀντιόχεια ἡ ἐπὶ Ὀρόντου, ''Antiókheia hē epì Oróntou'', Learned ; also Syrian Antioch) grc-koi, Ἀντιόχεια ἡ ἐπὶ Ὀρόντου; or Ἀντιόχεια ἡ ἐπ� ...
, a city he named after his father. An alternative capital was established at
Seleucia on the Tigris
Seleucia (; grc-gre, Σελεύκεια), also known as or , was a major Mesopotamian city of the Seleucid empire. It stood on the west bank of the Tigris River, within the present-day Baghdad Governorate in Iraq.
Name
Seleucia ( grc-gre, ...
, north of Babylon. Seleucus's empire reached its greatest extent following his defeat of his erstwhile ally, Lysimachus, at
Corupedion in 281 BC, after which Seleucus expanded his control to encompass western Anatolia. He hoped further to take control of Lysimachus's lands in Europe – primarily
Thrace
Thrace (; el, Θράκη, Thráki; bg, Тракия, Trakiya; tr, Trakya) or Thrake is a geographical and historical region in Southeast Europe, now split among Bulgaria, Greece, and Turkey, which is bounded by the Balkan Mountains to ...
and even
Macedonia
Macedonia most commonly refers to:
* North Macedonia, a country in southeastern Europe, known until 2019 as the Republic of Macedonia
* Macedonia (ancient kingdom), a kingdom in Greek antiquity
* Macedonia (Greece), a traditional geographic reg ...
itself, but was assassinated by
Ptolemy Ceraunus
Ptolemy Ceraunus ( grc-gre, Πτολεμαῖος Κεραυνός ; c. 319 BC – January/February 279 BC) was a member of the Ptolemaic dynasty and briefly king of Macedon. As the son of Ptolemy I Soter, he was originally heir to the thr ...
on landing in Europe.
His son and successor,
Antiochus I Soter, was left with an enormous realm consisting of nearly all of the Asian portions of the Empire, but faced with
Antigonus II Gonatas in Macedonia and
Ptolemy II Philadelphus
; egy, Userkanaenre Meryamun Clayton (2006) p. 208
, predecessor = Ptolemy I
, successor = Ptolemy III
, horus = ''ḥwnw-ḳni'Khunuqeni''The brave youth
, nebty = ''wr-pḥtj'Urpekhti''Great of strength
, golde ...
in Egypt, he proved unable to pick up where his father had left off in conquering the European portions of Alexander's empire.
Breakup of Central Asian territories
Antiochus I (reigned 281–261 BC) and his son and successor
Antiochus II Theos (reigned 261–246 BC) were faced with challenges in the west, including repeated wars with
Ptolemy II and a
Celt
The Celts (, see pronunciation for different usages) or Celtic peoples () are. "CELTS location: Greater Europe time period: Second millennium B.C.E. to present ancestry: Celtic a collection of Indo-European peoples. "The Celts, an ancien ...
ic invasion of
Asia Minor
Anatolia, tr, Anadolu Yarımadası), and the Anatolian plateau, also known as Asia Minor, is a large peninsula in Western Asia and the westernmost protrusion of the Asian continent. It constitutes the major part of modern-day Turkey. The ...
—distracting attention from holding the eastern portions of the Empire together. Towards the end of Antiochus II's reign, various provinces simultaneously asserted their independence, such as
Bactria
Bactria (; Bactrian: , ), or Bactriana, was an ancient region in Central Asia in Amu Darya's middle stream, stretching north of the Hindu Kush, west of the Pamirs and south of the Gissar range, covering the northern part of Afghanistan, so ...
and
Sogdia
Sogdia ( Sogdian: ) or Sogdiana was an ancient Iranian civilization between the Amu Darya and the Syr Darya, and in present-day Uzbekistan, Turkmenistan, Tajikistan, Kazakhstan, and Kyrgyzstan. Sogdiana was also a province of the Achaemenid Em ...
na under
Diodotus,
Cappadocia
Cappadocia or Capadocia (; tr, Kapadokya), is a historical region in Central Anatolia, Turkey. It largely is in the provinces Nevşehir, Kayseri, Aksaray, Kırşehir, Sivas and Niğde.
According to Herodotus, in the time of the Ionian Re ...
under
Ariarathes III
Ariarathes III ( grc, Ἀριαράθης, Ariaráthēs; reigned 262 or 255 – 220 BC), son of Ariaramnes, ruler of Cappadocia, and grandson of Ariarathes II, married Stratonice, a daughter of Antiochus II, king of the Seleucid Empire and wife ...
, and
Parthia
Parthia ( peo, 𐎱𐎼𐎰𐎺 ''Parθava''; xpr, 𐭐𐭓𐭕𐭅 ''Parθaw''; pal, 𐭯𐭫𐭮𐭥𐭡𐭥 ''Pahlaw'') is a historical region located in northeastern Greater Iran. It was conquered and subjugated by the empire of the Mede ...
under
Andragoras. A few years later, the last was defeated and killed by the invading
Parni of
Arsaces – the region would then become the core of the
Parthian Empire
The Parthian Empire (), also known as the Arsacid Empire (), was a major Iranian political and cultural power in ancient Iran from 247 BC to 224 AD. Its latter name comes from its founder, Arsaces I, who led the Parni tribe in conq ...
.
Diodotus, governor for the
Bactria
Bactria (; Bactrian: , ), or Bactriana, was an ancient region in Central Asia in Amu Darya's middle stream, stretching north of the Hindu Kush, west of the Pamirs and south of the Gissar range, covering the northern part of Afghanistan, so ...
n territory, asserted independence in around 245 BC, although the exact date is far from certain, to form the
Greco-Bactrian Kingdom
The Bactrian Kingdom, known to historians as the Greco-Bactrian Kingdom or simply Greco-Bactria, was a Hellenistic-era Greek state, and along with the Indo-Greek Kingdom, the easternmost part of the Hellenistic world in Central Asia and the Ind ...
. This kingdom was characterized by a rich
Hellenistic
In Classical antiquity, the Hellenistic period covers the time in Mediterranean history after Classical Greece, between the death of Alexander the Great in 323 BC and the emergence of the Roman Empire, as signified by the Battle of Actium i ...
culture and was to continue its domination of Bactria until around 125 BC when it was overrun by the invasion of northern nomads. One of the Greco-Bactrian kings,
Demetrius I of Bactria, invaded India around 180 BC to form the
Indo-Greek Kingdoms.
The rulers of
Persis, called
Fratarakas, also seem to have established some level of independence from the Seleucids during the 3rd century BC, especially from the time of
Vahbarz. They would later overtly take the title of
Kings of Persis, before becoming vassals to the newly formed
Parthian Empire
The Parthian Empire (), also known as the Arsacid Empire (), was a major Iranian political and cultural power in ancient Iran from 247 BC to 224 AD. Its latter name comes from its founder, Arsaces I, who led the Parni tribe in conq ...
.
The Seleucid satrap of Parthia, named
Andragoras, first claimed independence, in a parallel to the secession of his Bactrian neighbour. Soon after, however, a Parthian tribal chief called
Arsaces invaded the Parthian territory around 238 BC to form the
Arsacid dynasty, from which the
Parthian Empire
The Parthian Empire (), also known as the Arsacid Empire (), was a major Iranian political and cultural power in ancient Iran from 247 BC to 224 AD. Its latter name comes from its founder, Arsaces I, who led the Parni tribe in conq ...
originated.
Antiochus II's son
Seleucus II Callinicus came to the throne around 246 BC. Seleucus II was soon dramatically defeated in the
Third Syrian War against
Ptolemy III of Egypt and then had to fight a civil war against his own brother
Antiochus Hierax. Taking advantage of this distraction, Bactria and Parthia seceded from the empire. In Asia Minor too, the Seleucid dynasty seemed to be losing control: the Gauls had fully established themselves in
Galatia, semi-independent semi-Hellenized kingdoms had sprung up in
Bithynia
Bithynia (; Koine Greek: , ''Bithynía'') was an ancient region, kingdom and Roman province in the northwest of Asia Minor (present-day Turkey), adjoining the Sea of Marmara, the Bosporus, and the Black Sea. It bordered Mysia to the sout ...
,
Pontus, and
Cappadocia
Cappadocia or Capadocia (; tr, Kapadokya), is a historical region in Central Anatolia, Turkey. It largely is in the provinces Nevşehir, Kayseri, Aksaray, Kırşehir, Sivas and Niğde.
According to Herodotus, in the time of the Ionian Re ...
, and the city of
Pergamum in the west was asserting its independence under the
Attalid Dynasty. The Seleucid economy started to show the first signs of weakness, as Galatians gained independence and Pergamum took control of coastal cities in Anatolia. Consequently, they managed to partially block contact with the West.
Revival (223–191 BC)

A revival would begin when Seleucus II's younger son,
Antiochus III the Great, took the throne in 223 BC. Although initially unsuccessful in the
Fourth Syrian War against Egypt, which led to a defeat at the
Battle of Raphia (217 BC), Antiochus would prove himself to be the greatest of the Seleucid rulers after Seleucus I himself. He spent the next ten years on his
anabasis (journey) through the eastern parts of his domain and restoring rebellious vassals like Parthia and
Greco-Bactria to at least nominal obedience. He gained many victories such as the
Battle of Mount Labus and
Battle of the Arius and
besieged the Bactrian capital. He even emulated Seleucus with an expedition into India where he met with King
Sophagasenus (
Sanskrit
Sanskrit (; attributively , ; nominalization, nominally , , ) is a classical language belonging to the Indo-Aryan languages, Indo-Aryan branch of the Indo-European languages. It arose in South Asia after its predecessor languages had Trans-cul ...
: ''Subhagasena'') receiving war elephants, perhaps in accordance of the existing treaty and alliance set after the Seleucid-Mauryan War.
Actual translation of Polybius 11.34 (No other source except Polybius makes any reference to Sophagasenus):
When he returned to the west in 205 BC, Antiochus found that with the death of
Ptolemy IV, the situation now looked propitious for another western campaign. Antiochus and
Philip V of Macedon
Philip V ( grc-gre, Φίλιππος ; 238–179 BC) was king ( Basileus) of Macedonia from 221 to 179 BC. Philip's reign was principally marked by an unsuccessful struggle with the emerging power of the Roman Republic. He would lead Macedon aga ...
then made a pact to divide the Ptolemaic possessions outside of Egypt, and in the
Fifth Syrian War, the Seleucids ousted
Ptolemy V
egy, Iwaennetjerwymerwyitu Seteppah Userkare Sekhem-ankhamun Clayton (2006) p. 208.
, predecessor = Ptolemy IV
, successor = Ptolemy VI
, horus = '' ḥwnw-ḫꜤj-m-nsw-ḥr-st-jt.f'Khunukhaiemnisutkhersetitef'' The youth wh ...
from control of
Coele-Syria. The
Battle of Panium (200 BC) definitively transferred these holdings from the Ptolemies to the Seleucids. Antiochus appeared, at the least, to have restored the Seleucid Kingdom to glory.
Expansion into Greece and war with Rome

Following the defeat of his erstwhile ally
Philip by Rome in 197 BC, Antiochus saw the opportunity for expansion into Greece itself. Encouraged by the exiled
Carthaginian general
Hannibal
Hannibal (; xpu, 𐤇𐤍𐤁𐤏𐤋, ''Ḥannibaʿl''; 247 – between 183 and 181 BC) was a Carthaginian general and statesman who commanded the forces of Carthage in their battle against the Roman Republic during the Second Pu ...
, and making an alliance with the disgruntled
Aetolian League, Antiochus launched an invasion across the
Hellespont
The Dardanelles (; tr, Çanakkale Boğazı, lit=Strait of Çanakkale, el, Δαρδανέλλια, translit=Dardanéllia), also known as the Strait of Gallipoli from the Gallipoli peninsula or from Classical Antiquity as the Hellespont ( ...
. With his huge army he aimed to establish the Seleucid empire as the foremost power in the Hellenic world, but these plans put the empire on a collision course with the new rising power of the Mediterranean, the
Roman Republic
The Roman Republic ( la, Res publica Romana ) was a form of government of Rome and the era of the classical Roman civilization when it was run through public representation of the Roman people. Beginning with the overthrow of the Roman Kingd ...
. At the battles of
Thermopylae (191 BC) and
Magnesia (190 BC), Antiochus's forces suffered resounding defeats, and he was compelled to make peace and sign the
Treaty of Apamea
The Treaty of Apamea was a peace treaty conducted in 188 BC between the Roman Republic and Antiochus III, ruler of the Seleucid Empire. It ended the Roman–Seleucid War. The treaty took place after Roman victories at the Battle of Thermopyla ...
(188 BC), the main clause of which saw the Seleucids agree to pay a large indemnity, to retreat from
Anatolia
Anatolia, tr, Anadolu Yarımadası), and the Anatolian plateau, also known as Asia Minor, is a large peninsula in Western Asia and the westernmost protrusion of the Asian continent. It constitutes the major part of modern-day Turkey. The r ...
and to never again attempt to expand Seleucid territory west of the
Taurus Mountains
The Taurus Mountains (Turkish language, Turkish: ''Toros Dağları'' or ''Toroslar'') are a mountain range, mountain complex in southern Turkey, separating the Mediterranean Region, Turkey, Mediterranean coastal region from the central Anatolia# ...
. The
Kingdom of Pergamum
The Kingdom of Pergamon or Attalid kingdom was a Greek state during the Hellenistic period that ruled much of the Western part of Asia Minor from its capital city of Pergamon. It was ruled by the Attalid dynasty (; grc-x-koine, Δυναστε ...
and the
Republic of Rhodes, Rome's allies in the war, gained the former Seleucid lands in Anatolia. Antiochus died in 187 BC on another expedition to the east, where he sought to extract money to pay the indemnity.
Roman power, Parthia and Judea

The reign of his son and successor
Seleucus IV Philopator
Seleucus IV Philopator (Greek: Σέλευκος Φιλοπάτωρ; c. 218 – 3 September 175 BC), ruler of the Hellenistic Seleucid Empire, reigned from 187 BC to 175 BC over a realm consisting of Syria (now including Cilicia and Judea), Mes ...
(187–175 BC) was largely spent in attempts to pay the large indemnity, and Seleucus was ultimately assassinated by his minister
Heliodorus.
Seleucus' younger brother,
Antiochus IV Epiphanes
Antiochus IV Epiphanes (; grc, Ἀντίοχος ὁ Ἐπιφανής, ''Antíochos ho Epiphanḗs'', "God Manifest"; c. 215 BC – November/December 164 BC) was a Greek Hellenistic king who ruled the Seleucid Empire from 175 BC until his dea ...
, now seized the throne. He attempted to restore Seleucid power and prestige with a successful war against the old enemy,
Ptolemaic Egypt, which met with initial success as the Seleucids defeated and drove the Egyptian army back to
Alexandria
Alexandria ( or ; ar, ٱلْإِسْكَنْدَرِيَّةُ ; grc-gre, Αλεξάνδρεια, Alexándria) is the second largest city in Egypt, and the largest city on the Mediterranean coast. Founded in by Alexander the Great, Alexandr ...
itself. As the king planned on how to conclude the war, he was informed that Roman commissioners, led by the
Proconsul
A proconsul was an official of ancient Rome who acted on behalf of a consul. A proconsul was typically a former consul. The term is also used in recent history for officials with delegated authority.
In the Roman Republic, military command, or ' ...
Gaius Popillius Laenas, were near and requesting a meeting with the Seleucid king. Antiochus agreed, but when they met and Antiochus held out his hand in friendship, Popilius placed in his hand the tablets on which was written the decree of the senate and told him to read it. The decree demanded that he should abort his attack on Alexandria and immediately stop waging the war on Ptolemy. When the king said that he would call his friends into council and consider what he ought to do, Popilius drew a circle in the sand around the king's feet with the stick he was carrying and said, "Before you step out of that circle give me a reply to lay before the senate." For a few moments he hesitated, astounded at such a peremptory order, and at last replied, "I will do what the senate thinks right." He then chose to withdraw rather than set the empire to war with Rome again.
On his return journey, according to
Josephus
Flavius Josephus (; grc-gre, Ἰώσηπος, ; 37 – 100) was a first-century Romano-Jewish historian and military leader, best known for '' The Jewish War'', who was born in Jerusalem—then part of Roman Judea—to a father of priestly d ...
, he made an expedition to
Judea
Judea or Judaea ( or ; from he, יהודה, Standard ''Yəhūda'', Tiberian ''Yehūḏā''; el, Ἰουδαία, ; la, Iūdaea) is an ancient, historic, Biblical Hebrew, contemporaneous Latin, and the modern-day name of the mountainous south ...
, took
Jerusalem
Jerusalem (; he, יְרוּשָׁלַיִם ; ar, القُدس ) (combining the Biblical and common usage Arabic names); grc, Ἱερουσαλήμ/Ἰεροσόλυμα, Hierousalḗm/Hierosóluma; hy, Երուսաղեմ, Erusałēm. i ...
by force, slew a great many who had favored
Ptolemy
Claudius Ptolemy (; grc-gre, Πτολεμαῖος, ; la, Claudius Ptolemaeus; AD) was a mathematician, astronomer, astrologer, geographer, and music theorist, who wrote about a dozen scientific treatises, three of which were of import ...
, sent his soldiers to plunder them without mercy. He also spoiled the
temple
A temple (from the Latin ) is a building reserved for spiritual rituals and activities such as prayer and sacrifice. Religions which erect temples include Christianity (whose temples are typically called church (building), churches), Hindui ...
, and interrupted the constant practice of offering a daily sacrifice of expiation, for three years and six months.
The latter part of his reign saw a further disintegration of the Empire despite his best efforts. Weakened economically, militarily and by loss of prestige, the Empire became vulnerable to rebels in the eastern areas of the empire, who began to further undermine the empire while the Parthians moved into the power vacuum to take over the old Persian lands. Antiochus' aggressive Hellenizing (or de-Judaizing) activities provoked a full scale armed rebellion in
Judea
Judea or Judaea ( or ; from he, יהודה, Standard ''Yəhūda'', Tiberian ''Yehūḏā''; el, Ἰουδαία, ; la, Iūdaea) is an ancient, historic, Biblical Hebrew, contemporaneous Latin, and the modern-day name of the mountainous south ...
—the