Red-haired Siblings
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Red hair, also known as ginger hair, is a
human hair color Human hair color is the pigmentation of human hair follicles and hair, shafts due to two types of melanin: eumelanin and pheomelanin. Generally, the more melanin present, the darker the hair. Its tone depends on the ratio of black or brown eum ...
found in 2–6% of people of Northern or
Northwestern Europe Northwestern Europe, or Northwest Europe, is a loosely defined subregion of Europe, overlapping Northern and Western Europe. The term is used in geographic, history, and military contexts. Geographic definitions Geographically, Northwestern ...
an ancestry and lesser frequency in other populations. It is most common in individuals
homozygous Zygosity (the noun, zygote, is from the Greek "yoked," from "yoke") () is the degree to which both copies of a chromosome or gene have the same genetic sequence. In other words, it is the degree of similarity of the alleles in an organism. Mos ...
for a recessive allele on chromosome 16 that produces an altered version of the MC1R protein. Red hair varies in hue from a deep
burgundy Burgundy ( ; ; Burgundian: ''Bregogne'') is a historical territory and former administrative region and province of east-central France. The province was once home to the Dukes of Burgundy from the early 11th until the late 15th century. ...
or bright
copper Copper is a chemical element; it has symbol Cu (from Latin ) and atomic number 29. It is a soft, malleable, and ductile metal with very high thermal and electrical conductivity. A freshly exposed surface of pure copper has a pinkish-orang ...
, or auburn, to burnt orange or red-orange to strawberry blond. Characterized by high levels of the reddish pigment
pheomelanin Melanin (; ) is a family of biomolecules organized as oligomers or polymers, which among other functions provide the Biological pigment, pigments of many organisms. Melanin pigments are produced in a specialized group of cells known as melan ...
and relatively low levels of the dark pigment
eumelanin Melanin (; ) is a family of biomolecules organized as oligomers or polymers, which among other functions provide the pigments of many organisms. Melanin pigments are produced in a specialized group of cells known as melanocytes. There are ...
, it is typically associated with fair skin color, lighter
eye color Eye color is a polygene, polygenic phenotypic trait determined by two factors: the pigmentation of the eye's Iris (anatomy), iris and the frequency-dependence of the scattering of light by the Turbidity, turbid medium in the Stroma of iris, str ...
, freckles, and sensitivity to
ultraviolet light Ultraviolet radiation, also known as simply UV, is electromagnetic radiation of wavelengths of 10–400 nanometers, shorter than that of visible light, but longer than X-rays. UV radiation is present in sunlight and constitutes about 10% of th ...
. Cultural reactions to red hair have been varied. The term "redhead" has been in use since at least 1510, while the term "ginger" is sometimes used, especially in Britain and Ireland, to describe a person with red hair. The origin of red hair can be traced to
Central Asia Central Asia is a region of Asia consisting of Kazakhstan, Kyrgyzstan, Tajikistan, Turkmenistan, and Uzbekistan. The countries as a group are also colloquially referred to as the "-stans" as all have names ending with the Persian language, Pers ...
, caused by a mutation in the MC1R gene.


Geographic distribution


Modern


Northern and Northwestern Europe

Red hair is most commonly found at the northern and western fringes of Europe; it is centred around populations in the
British Isles The British Isles are an archipelago in the Atlantic Ocean, North Atlantic Ocean off the north-western coast of continental Europe, consisting of the islands of Great Britain, Ireland, the Isle of Man, the Inner Hebrides, Inner and Outer Hebr ...
and is particularly associated with the
Celtic nations The Celtic nations or Celtic countries are a cultural area and collection of geographical regions in Northwestern Europe where the Celtic languages and cultural traits have survived. The term ''nation'' is used in its original sense to mean a ...
.
Ireland Ireland (, ; ; Ulster Scots dialect, Ulster-Scots: ) is an island in the North Atlantic Ocean, in Northwestern Europe. Geopolitically, the island is divided between the Republic of Ireland (officially Names of the Irish state, named Irelan ...
and
Scotland Scotland is a Countries of the United Kingdom, country that is part of the United Kingdom. It contains nearly one-third of the United Kingdom's land area, consisting of the northern part of the island of Great Britain and more than 790 adjac ...
have the highest number of red-haired people per capita in the world, with the percentage of those with red hair at around 10% in Ireland and between 5-13% in Scotland. The highest concentration of red head carriers in the world is found in
Edinburgh Edinburgh is the capital city of Scotland and one of its 32 Council areas of Scotland, council areas. The city is located in southeast Scotland and is bounded to the north by the Firth of Forth and to the south by the Pentland Hills. Edinburgh ...
, making it the red head capital of the world. In 1907, the largest ever study of hair colour in Scotland, which analysed over 500,000 people, found the percentage of Scots with red hair to be 5.3%.


Eastern Europe

Byzantine The Byzantine Empire, also known as the Eastern Roman Empire, was the continuation of the Roman Empire centred on Constantinople during late antiquity and the Middle Ages. Having survived the events that caused the fall of the Western Roman E ...
writers
Jordanes Jordanes (; Greek language, Greek: Ιορδάνης), also written as Jordanis or Jornandes, was a 6th-century Eastern Roman bureaucrat, claimed to be of Goths, Gothic descent, who became a historian later in life. He wrote two works, one on R ...
and
Procopius Procopius of Caesarea (; ''Prokópios ho Kaisareús''; ; – 565) was a prominent Late antiquity, late antique Byzantine Greeks, Greek scholar and historian from Caesarea Maritima. Accompanying the Roman general Belisarius in Justinian I, Empe ...
described the early Slavic peoples as having ruddy hair and skin tone. Later by the 10th century, Southern Slavic populations would have darker hair and skin tone, as the Slavs assimilated the indigenous inhabitants of the Balkans, including
Greek Greek may refer to: Anything of, from, or related to Greece, a country in Southern Europe: *Greeks, an ethnic group *Greek language, a branch of the Indo-European language family **Proto-Greek language, the assumed last common ancestor of all kno ...
and Illyrian peoples. In the late 18th century,
ethnographers Ethnography is a branch of anthropology and the systematic study of individual cultures. It explores cultural phenomena from the point of view of the subject of the study. Ethnography is also a type of social research that involves examining ...
considered the Udmurt people of the Volga Region in Russia to be "the most red-headed men in the world". The Volga region still has one of the highest percentages of red-headed people. Red hair is also found amongst the
Ashkenazi Ashkenazi Jews ( ; also known as Ashkenazic Jews or Ashkenazim) form a distinct subgroup of the Jewish diaspora, that Ethnogenesis, emerged in the Holy Roman Empire around the end of the first millennium Common era, CE. They traditionally spe ...
Jewish populations. In 1903, 5.6% of Polish Jews had red hair. Other studies have found that 3.69% of Jewish women overall were found to have red hair, but around 10.9% of all Jewish men have red
beards A beard is the hair that grows on the jaw, chin, upper lip, lower lip, cheeks, and neck of humans and some non-human animals. In humans, beards are most commonly seen on Puberty, pubescent or adult males, though women have been observed with ...
. The
stereotype In social psychology, a stereotype is a generalization, generalized belief about a particular category of people. It is an expectation that people might have about every person of a particular group. The type of expectation can vary; it can ...
that red hair is Jewish remains in parts of Eastern Europe and Russia.


Southern Europe

In Italy, red hair is found at a frequency of 0.57% of the total population, without variation in frequency across the different regions of the country.''Consanguinity, Inbreeding, and Genetic Drift in Italy'', Princeton University Press, 15 Feb 2013, Luigi Luca Cavalli-Sforza, Antonio Moroni, Gianna Zei, page 270 In Sardinia, red hair is found at a frequency of 0.24% of the population. In Italy, red hair was associated with Italian Jews, and Judas was traditionally depicted as red-haired in Italian and Spanish art. In European culture, before the 20th century, red hair was often seen as a stereotypically Jewish trait: during the
Spanish Inquisition The Tribunal of the Holy Office of the Inquisition () was established in 1478 by the Catholic Monarchs of Spain, Catholic Monarchs, King Ferdinand II of Aragon and Queen Isabella I of Castile and lasted until 1834. It began toward the end of ...
, all those with red hair were identified as Jewish.


North Africa and Mediterranean

The
Berber Berber or Berbers may refer to: Ethnic group * Berbers, an ethnic group native to Northern Africa * Berber languages, a family of Afro-Asiatic languages Places * Berber, Sudan, a town on the Nile People with the surname * Ady Berber (1913–196 ...
populations of
Morocco Morocco, officially the Kingdom of Morocco, is a country in the Maghreb region of North Africa. It has coastlines on the Mediterranean Sea to the north and the Atlantic Ocean to the west, and has land borders with Algeria to Algeria–Morocc ...
and northern
Algeria Algeria, officially the People's Democratic Republic of Algeria, is a country in the Maghreb region of North Africa. It is bordered to Algeria–Tunisia border, the northeast by Tunisia; to Algeria–Libya border, the east by Libya; to Alger ...
have occasional redheads. Red hair frequency is especially significant among the Riffians from Morocco and Kabyles from Algeria, respectively.


Asia (all regions)

In Asia, red hair can be found among some peoples of Afghan,
Arab Arabs (,  , ; , , ) are an ethnic group mainly inhabiting the Arab world in West Asia and North Africa. A significant Arab diaspora is present in various parts of the world. Arabs have been in the Fertile Crescent for thousands of years ...
,
Iranian Iranian () may refer to: * Something of, from, or related to Iran ** Iranian diaspora, Iranians living outside Iran ** Iranian architecture, architecture of Iran and parts of the rest of West Asia ** Iranian cuisine, cooking traditions and practic ...
, East Indians, Mongolian, Turkic, Miao, and Hmong descent. Several preserved samples of human hair have been obtained from an
Iron Age The Iron Age () is the final epoch of the three historical Metal Ages, after the Chalcolithic and Bronze Age. It has also been considered as the final age of the three-age division starting with prehistory (before recorded history) and progre ...
cemetery in Khakassia, South Siberia. Many of the hair samples appear red in color, and one skull from the cemetery had a preserved red
moustache A moustache (; mustache, ) is a growth of facial hair grown above the upper lip and under the human nose, nose. Moustaches have been worn in various styles throughout history. Etymology The word "moustache" is French language, French, and i ...
. Ancient human remains described as having red or auburn hair have been discovered in various parts of Asia, including the
Tarim mummies The Tarim mummies are a series of Mummy, mummies discovered in the Tarim Basin in present-day Xinjiang, China, which date from Tarim Basin#Early periods, 1800 BCE to the first centuries BCE, with a new group of individuals recently dated to betw ...
of
Xinjiang Xinjiang,; , SASM/GNC romanization, SASM/GNC: Chinese postal romanization, previously romanized as Sinkiang, officially the Xinjiang Uygur Autonomous Region (XUAR), is an Autonomous regions of China, autonomous region of the China, People' ...
, China. In Chinese sources, ancient
Kyrgyz people The Kyrgyz people (also spelled Kyrghyz, Kirgiz, and Kirghiz; or ) are a Turkic peoples, Turkic ethnic group native to Central Asia. They primarily reside in Kyrgyzstan, Uzbekistan, and China. A Kyrgyz diaspora is also found in Russia, Tajik ...
were described as fair-skinned, green- or blue-eyed and red-haired people with a mixture of European and East Asian features. In the Book of Wei, Chinese author
Wei Shou Wei Shou () (506–572), courtesy name Boqi (伯起), was a Chinese people, Chinese author born in Quyang County in Julu Commandery (today Xingtai, Hebei) who served under the Northern Qi, Northern Qi dynasty.(魏收,字伯起,小字佛助,� ...
notes that Liu Yuan was over tall and had red strands of hair in his long beard. The ethnic
Miao people Miao is a word that the Chinese use to designate some ethnic minority groups living in southern China and Mainland Southeast Asia. Miao is thus officially recognized by the Chinese government as one of the largest ethnic minority groups that h ...
of China are recorded with red hair. According to F.M Savina of the Paris Foreign Missionary Society, the appearance of the Miao was "pale yellow in complexion, almost white, their hair is often light or dark brown, sometimes even red or corn-silk blond, and a few even have pale blue eyes". A phenotype study of
Hmong people The Hmong people ( RPA: , CHV: ''Hmôngz'', Nyiakeng Puachue: , Pahawh Hmong: , , zh, c=苗族蒙人) are an indigenous group in East Asia and Southeast Asia. In China, the Hmong people are classified as a sub-group of the Miao people. Th ...
show they are sometimes born with red hair. The Kipchak people were a Turkic ethnic group from Central Asia who served in the
Golden Horde The Golden Horde, self-designated as ''Ulug Ulus'' ( in Turkic) was originally a Mongols, Mongol and later Turkicized khanate established in the 13th century and originating as the northwestern sector of the Mongol Empire. With the division of ...
military forces after being conquered by the Mongols. In the Chinese historical document ''Kang mu'', the Kipchak people are described as red haired and blue-eyed.


Americas, Oceania and Sub-Saharan Africa

Reddish-brown ( auburn) hair is also found among some
Polynesians Polynesians are an ethnolinguistic group comprising closely related ethnic groups native to Polynesia, which encompasses the islands within the Polynesian Triangle in the Pacific Ocean. They trace their early prehistoric origins to Island Sout ...
, and is especially common in some tribes and family groups. In Polynesian culture, reddish hair has traditionally been seen as a sign of descent from high-ranking ancestors and a mark of rulership. Emigration from Europe has increased the population of red haired humans in the Americas, Australia, New Zealand and
South Africa South Africa, officially the Republic of South Africa (RSA), is the Southern Africa, southernmost country in Africa. Its Provinces of South Africa, nine provinces are bounded to the south by of coastline that stretches along the Atlantic O ...
.


Historical

Several accounts by Greek writers mention redheaded people. A fragment by the poet
Xenophanes Xenophanes of Colophon ( ; ; – c. 478 BC) was a Greek philosopher, theologian, poet, and critic of Homer. He was born in Ionia and travelled throughout the Greek-speaking world in early classical antiquity. As a poet, Xenophanes was known f ...
describes the
Thracians The Thracians (; ; ) were an Indo-European languages, Indo-European speaking people who inhabited large parts of Southeast Europe in ancient history.. "The Thracians were an Indo-European people who occupied the area that today is shared betwee ...
as blue-eyed and red-haired. The ancient Budini and
Sarmatians The Sarmatians (; ; Latin: ) were a large confederation of Ancient Iranian peoples, ancient Iranian Eurasian nomads, equestrian nomadic peoples who dominated the Pontic–Caspian steppe, Pontic steppe from about the 5th century BCE to the 4t ...
are also reported by some classical Greek authors to be blue-eyed and red-haired. It was once believed that Sarmatians owed their name to their red hair, but this claim was later debunked. In Asia, red or auburn hair has been found among the ancient
Tocharians The Tocharians or Tokharians ( ; ) were speakers of the Tocharian languages, a group of Indo-European languages known from around 7,600 documents from the 6th and 7th centuries, found on the northern edge of the Tarim Basin (modern-day Xinj ...
, who occupied the
Tarim Basin The Tarim Basin is an endorheic basin in Xinjiang, Northwestern China occupying an area of about and one of the largest basins in Northwest China.Chen, Yaning, et al. "Regional climate change and its effects on river runoff in the Tarim Basin, Ch ...
in what is now the northwesternmost province of China.
Tarim mummies The Tarim mummies are a series of Mummy, mummies discovered in the Tarim Basin in present-day Xinjiang, China, which date from Tarim Basin#Early periods, 1800 BCE to the first centuries BCE, with a new group of individuals recently dated to betw ...
have been found with red hair dating to the
2nd millennium BC File:2nd millennium BC montage.jpg, 400x400px, From top left clockwise: Hammurabi, Babylonian king, best known for his Code of Hammurabi, code of laws; The gold Mask of Tutankhamun, funerary mask of Tutankhamun has become a symbol of ancient Egypt ...
. In certain Biblical accounts,
Hebrew Hebrew (; ''ʿÎbrit'') is a Northwest Semitic languages, Northwest Semitic language within the Afroasiatic languages, Afroasiatic language family. A regional dialect of the Canaanite languages, it was natively spoken by the Israelites and ...
and
Israelite Israelites were a Hebrew language, Hebrew-speaking ethnoreligious group, consisting of tribes that lived in Canaan during the Iron Age. Modern scholarship describes the Israelites as emerging from indigenous Canaanites, Canaanite populations ...
individuals were described as having ruddy hair. For example,
Esau Esau is the elder son of Isaac in the Hebrew Bible. He is mentioned in the Book of Genesis and by the minor prophet, prophets Obadiah and Malachi. The story of Jacob and Esau reflects the historical relationship between Israel and Edom, aiming ...
and
David David (; , "beloved one") was a king of ancient Israel and Judah and the third king of the United Monarchy, according to the Hebrew Bible and Old Testament. The Tel Dan stele, an Aramaic-inscribed stone erected by a king of Aram-Dam ...
(Gen. 25:25; 1 Sam. 16:12, 17:42.), are described as "''admoni''", meaning red or ruddy.


Biochemistry and genetics

The pigment
pheomelanin Melanin (; ) is a family of biomolecules organized as oligomers or polymers, which among other functions provide the Biological pigment, pigments of many organisms. Melanin pigments are produced in a specialized group of cells known as melan ...
gives red hair its distinctive color. Red hair has far more of the pigment pheomelanin than it has of the dark pigment eumelanin. The
genetics Genetics is the study of genes, genetic variation, and heredity in organisms.Hartl D, Jones E (2005) It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinians, Augustinian ...
of red hair appear to be associated with the melanocortin-1 receptor (MC1R), which is found on chromosome 16. In 1995, Valverde, et al. identified
allele An allele is a variant of the sequence of nucleotides at a particular location, or Locus (genetics), locus, on a DNA molecule. Alleles can differ at a single position through Single-nucleotide polymorphism, single nucleotide polymorphisms (SNP), ...
s on MC1R associated with red hair. The number of alleles linked to red hair has since been expanded by other authors, and these variants are now identified as the RHC (''red hair colour'') alleles. Eighty percent of redheads have an MC1R gene variant within the RHC. Red hair is also associated with fair skin color because the MC1R mutation also results in low concentrations of eumelanin throughout the body. The lower melanin concentration in skin confers the advantage that a sufficient concentration of important
vitamin D Vitamin D is a group of structurally related, fat-soluble compounds responsible for increasing intestinal absorption of calcium, magnesium, and phosphate, along with numerous other biological functions. In humans, the most important compo ...
can be produced under low light conditions. However, when UV-radiation is strong (as in regions close to the equator) the lower concentration of melanin leads to several medical disadvantages, such as a higher risk of skin cancer. The MC1R variant gene that gives people red hair generally results in skin that is difficult or impossible to tan. Because of the natural tanning reaction to the sun's ultraviolet light and high amounts of pheomelanin in the skin, freckles are a common, but not universal, feature of red-haired people. Red hair can originate from several changes on the MC1R-gene. If one of these changes is present on both chromosomes, then the respective individual is likely to have red hair. This type of inheritance is described as an autosomal
recessive In genetics, dominance is the phenomenon of one variant (allele) of a gene on a chromosome masking or overriding the effect of a different variant of the same gene on the other copy of the chromosome. The first variant is termed dominant and ...
. Even if both parents do not have red hair themselves, both can be carriers for the gene and have a redheaded child. Genetic studies of dizygotic (fraternal) twins indicate that the MC1R gene is not solely responsible for the red hair phenotype; unidentified modifier genes exist, making variance in the MC1R gene necessary, but not sufficient, for red hair production.


Genetics

The alleles Arg151Cys, Arg160Trp, Asp294His, and Arg142His on MC1R are shown to be recessives for the red hair phenotype. The gene ''HCL2'' on chromosome 4 may also be related to red hair. There are at least 8 genetic differences associated with red hair color. In species other than primates, red hair has different genetic origins and mechanisms.


Beards

The genes responsible for red hair can express themselves to different extents in different people. One consequence of this is that a number of people have both dark hair and red beards. This may reflect the presence of a single copy of the MC1R gene, leading to differential expression in the beard versus the scalp hair. However, some red-bearded people lack MC1R genes.


Evolution


Origins

Red hair is the rarest natural hair color in humans. The non-tanning skin associated with red hair may have been advantageous in far-northern climates where sunlight is scarce. Studies by Bodmer and Cavalli-Sforza (1976) hypothesized that lighter skin pigmentation prevents
rickets Rickets, scientific nomenclature: rachitis (from Greek , meaning 'in or of the spine'), is a condition that results in weak or soft bones in children and may have either dietary deficiency or genetic causes. Symptoms include bowed legs, stun ...
in colder climates by encouraging higher levels of
vitamin D Vitamin D is a group of structurally related, fat-soluble compounds responsible for increasing intestinal absorption of calcium, magnesium, and phosphate, along with numerous other biological functions. In humans, the most important compo ...
production and also allows the individual to retain heat better than someone with darker skin. In 2000, Harding ''et al.'' concluded that red hair is not the result of positive selection but of a lack of negative selection. In Africa, for example, red hair is selected against because high levels of sun harm pale skin. However, in Northern Europe this does not happen, so redheads can become more common through
genetic drift Genetic drift, also known as random genetic drift, allelic drift or the Wright effect, is the change in the Allele frequency, frequency of an existing gene variant (allele) in a population due to random chance. Genetic drift may cause gene va ...
. Estimates on the original occurrence of the currently active gene for red hair vary from 20,000 to 100,000 years ago. A DNA study of
Neanderthal Neanderthals ( ; ''Homo neanderthalensis'' or sometimes ''H. sapiens neanderthalensis'') are an extinction, extinct group of archaic humans who inhabited Europe and Western and Central Asia during the Middle Pleistocene, Middle to Late Plei ...
genomes determined that the MC1R gene resulting in red hair in modern humans was not present in Neanderthal, and "if variants contributing to red hair were present in Neanderthals, they were probably not at high frequency."


Extinction hoax

A 2007 report in ''
The Courier-Mail ''The Courier-Mail'' is an Australian newspaper published in Brisbane. Owned by News Corp Australia, it is published daily from Monday to Saturday in tabloid format. Its editorial offices are located at Bowen Hills, in Brisbane's inner norther ...
'', which cited the ''
National Geographic ''National Geographic'' (formerly ''The National Geographic Magazine'', sometimes branded as ''Nat Geo'') is an American monthly magazine published by National Geographic Partners. The magazine was founded in 1888 as a scholarly journal, nine ...
'' magazine and unnamed "geneticists", said that red hair is likely to die out in the near future. Other blogs and news sources ran similar stories that attributed the research to the magazine or the "Oxford Hair Foundation". However, a
HowStuffWorks HowStuffWorks is an American commercial infotainment website founded by professor and author Marshall Brain, to provide its target audience an insight into the way many things work. The site uses various media to explain complex concepts, term ...
article says that the foundation was funded by hair-dye maker
Procter & Gamble The Procter & Gamble Company (P&G) is an American multinational consumer goods corporation headquartered in Cincinnati, Ohio. It was founded in 1837 by William Procter and James Gamble. It specializes in a wide range of personal health/con ...
, and that other experts had dismissed the research as either lacking in evidence or simply bogus. The ''National Geographic'' article in fact states, "while redheads may decline, the potential for red isn't going away".Redhead extinction
HowStuffWorks HowStuffWorks is an American commercial infotainment website founded by professor and author Marshall Brain, to provide its target audience an insight into the way many things work. The site uses various media to explain complex concepts, term ...
. Retrieved 28 June 2009.
Red hair is caused by a relatively rare recessive
allele An allele is a variant of the sequence of nucleotides at a particular location, or Locus (genetics), locus, on a DNA molecule. Alleles can differ at a single position through Single-nucleotide polymorphism, single nucleotide polymorphisms (SNP), ...
, the expression of which can skip generations. It is not likely to disappear at any time in the foreseeable future.


Medical implications of the red hair gene


Melanoma

Melanin Melanin (; ) is a family of biomolecules organized as oligomers or polymers, which among other functions provide the pigments of many organisms. Melanin pigments are produced in a specialized group of cells known as melanocytes. There are ...
in the skin aids UV tolerance through
sun tanning Sun tanning or tanning is the process whereby skin color is darkened or tanned. It is most often a result of exposure to ultraviolet (UV) radiation from sunlight or from artificial sources, such as a tanning lamp found in indoor tanning b ...
, but fair-skinned persons lack the levels of melanin needed to prevent UV-induced DNA-damage. Studies have shown that red hair alleles in MC1R increase freckling and decrease tanning ability. It has been found that Europeans who are
heterozygous Zygosity (the noun, zygote, is from the Greek "yoked," from "yoke") () is the degree to which both copies of a chromosome or gene have the same genetic sequence. In other words, it is the degree of similarity of the alleles in an organism. Mos ...
for red hair exhibit increased sensitivity to UV radiation. Red hair and its relationship to UV sensitivity are of interest to many
melanoma Melanoma is the most dangerous type of skin cancer; it develops from the melanin-producing cells known as melanocytes. It typically occurs in the skin, but may rarely occur in the mouth, intestines, or eye (uveal melanoma). In very rare case ...
researchers. Sunshine can both be good and bad for a person's health and the different alleles on MC1R represent these adaptations. It also has been shown that individuals with pale skin are highly susceptible to a variety of
skin cancer Skin cancers are cancers that arise from the Human skin, skin. They are due to the development of abnormal cells (biology), cells that have the ability to invade or metastasis, spread to other parts of the body. It occurs when skin cells grow ...
s such as
melanoma Melanoma is the most dangerous type of skin cancer; it develops from the melanin-producing cells known as melanocytes. It typically occurs in the skin, but may rarely occur in the mouth, intestines, or eye (uveal melanoma). In very rare case ...
,
basal cell carcinoma Basal-cell carcinoma (BCC), also known as basal-cell cancer, basalioma, or rodent ulcer, is the most common type of skin cancer. It often appears as a painless, raised area of skin, which may be shiny with Telangiectasia, small blood vessels ru ...
, and
squamous cell carcinoma Squamous-cell carcinoma (SCC), also known as epidermoid carcinoma, comprises a number of different types of cancer that begin in squamous cells. These cells form on the surface of the skin, on the lining of hollow organs in the body, and on the ...
.


Pain tolerance and injury

Two studies have demonstrated that people with red hair have different sensitivity to pain to people with other hair colors. One study found that women with red hair are slightly more sensitive to thermal pain (associated with naturally occurring low
vitamin K Vitamin K is a family of structurally similar, fat-soluble vitamers found in foods and marketed as dietary supplements. The human body requires vitamin K for post-translational modification, post-synthesis modification of certain proteins ...
levels) and that
lidocaine Lidocaine, also known as lignocaine and sold under the brand name Xylocaine among others, is a local anesthetic of the amino amide type. It is also used to treat ventricular tachycardia and ventricular fibrillation. When used for local anae ...
was significantly less effective in reducing pain. Another study concluded that redheads are less sensitive to pain from multiple modalities, including
noxious stimuli A noxious stimulus is a stimulus strong enough to threaten the body's integrity (i.e. cause damage to tissue). Noxious stimulation induces peripheral afferents responsible for transducing pain (including A-delta and C- nerve fibers, as well a ...
such as electrically induced pain. Researchers have found that people with red hair require greater amounts of anesthetic. Another study showed women with gene variants associated with red hair had a greater
analgesic An analgesic drug, also called simply an analgesic, antalgic, pain reliever, or painkiller, is any member of the group of drugs used for pain management. Analgesics are conceptually distinct from anesthetics, which temporarily reduce, and in s ...
response to the painkiller pentazocine than do either women of other hair colors or men of any hair color. A follow-up study by the same group showed that men and women with red hair had a greater analgesic response to
morphine-6-glucuronide Morphine-6-glucuronide (M6G) is a major active metabolite of morphine. M6G is formed from morphine by the enzyme UGT2B7. It has analgesic effects roughly half that of morphine. M6G can accumulate to toxic levels in kidney failure. History of di ...
. However, a later study of 468 healthy adult patients found no significant difference in recovery times, pain scores, or quality of recovery in those with red hair compared with dark hair in either men or women. The unexpected relationship of hair color to pain tolerance appears to exist because redheads have a mutation in a hormone receptor that can apparently respond to at least two types of hormones: the pigmentation-driving
melanocyte-stimulating hormone The melanocyte-stimulating hormones, known collectively as MSH, also known as melanotropins or intermedins, are a family of peptide hormones and neuropeptides consisting of α-melanocyte-stimulating hormone (α-MSH), β-melanocyte-stimulating ...
(MSH), and the pain-relieving endorphins (both derive from the same precursor molecule, POMC, and are structurally similar). Specifically, redheads have a mutated melanocortin-1 receptor (MC1R) gene that produces an altered receptor for MSH. Melanocytes, the cells that produce pigment in skin and hair, use the MC1R to recognize and respond to MSH from the
anterior pituitary The anterior pituitary (also called the adenohypophysis or pars anterior) is a major Organ (anatomy), organ of the endocrine system. The anterior pituitary is the glandular, Anatomical terms of location#Usage in human anatomy, anterior lobe that t ...
gland. Melanocyte-stimulating hormones normally stimulates melanocytes to make black
eumelanin Melanin (; ) is a family of biomolecules organized as oligomers or polymers, which among other functions provide the pigments of many organisms. Melanin pigments are produced in a specialized group of cells known as melanocytes. There are ...
, but if the melanocytes have a mutated receptor, they will make reddish
pheomelanin Melanin (; ) is a family of biomolecules organized as oligomers or polymers, which among other functions provide the Biological pigment, pigments of many organisms. Melanin pigments are produced in a specialized group of cells known as melan ...
instead. MC1R also occurs in the brain, where it is one of a large set of POMC-related receptors that are apparently involved not only in responding to MSH, but also in responses to endorphins and possibly other POMC-derived hormones. Though the details are not clearly understood, it appears that there is some
crosstalk In electronics, crosstalk (XT) is a phenomenon by which a signal transmitted on one circuit or channel of a transmission system creates an undesired effect in another circuit or channel. Crosstalk is usually caused by undesired capacitive, ...
between the POMC hormones that may explain the link between red hair and pain tolerance. There is little or no evidence to support the belief that people with red hair have a higher chance than people with other hair colors to
hemorrhage Bleeding, hemorrhage, haemorrhage or blood loss, is blood escaping from the circulatory system from damaged blood vessels. Bleeding can occur internally, or externally either through a natural opening such as the mouth, nose, ear, urethra, ...
or suffer other bleeding complications. One study, however, reports a link between red hair and a higher rate of bruising.


Red hair of pathological origin

Most red hair is caused by the MC1R gene and is non-pathological. However, in rare cases red hair can be associated with disease or genetic disorders: * In cases of severe
malnutrition Malnutrition occurs when an organism gets too few or too many nutrients, resulting in health problems. Specifically, it is a deficiency, excess, or imbalance of energy, protein and other nutrients which adversely affects the body's tissues a ...
, normally dark human hair may turn red or blonde. The condition, part of a syndrome known as
kwashiorkor Kwashiorkor ( , is also ) is a form of severe protein malnutrition characterized by edema and an enlarged liver with fatty infiltrates. It is thought to be caused by sufficient calorie intake, but with insufficient protein consumption (or lac ...
, is a sign of critical starvation caused chiefly by
protein Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residue (biochemistry), residues. Proteins perform a vast array of functions within organisms, including Enzyme catalysis, catalysing metab ...
deficiency, and is common during periods of
famine A famine is a widespread scarcity of food caused by several possible factors, including, but not limited to war, natural disasters, crop failure, widespread poverty, an Financial crisis, economic catastrophe or government policies. This phenom ...
. * One variety of
albinism Albinism is the congenital absence of melanin in an animal or plant resulting in white hair, feathers, scales and skin and reddish pink or blue eyes. Individuals with the condition are referred to as albinos. Varied use and interpretation of ...
(Type 3, a.k.a. rufous albinism), sometimes seen in Africans and inhabitants of
New Guinea New Guinea (; Hiri Motu: ''Niu Gini''; , fossilized , also known as Papua or historically ) is the List of islands by area, world's second-largest island, with an area of . Located in Melanesia in the southwestern Pacific Ocean, the island is ...
, results in red hair and red-colored skin.Pathology Guy: Accumulations and Deposits
Ed Friedlander, M.D., Pathologist. Last updated 24 September 2006
* Red hair is found on people lacking
pro-opiomelanocortin Pro-opiomelanocortin (POMC) is a precursor polypeptide with 241 amino acid residues. POMC is Protein biosynthesis, synthesized in Corticotropic cell, corticotrophs of the anterior pituitary from the 267-amino-acid-long Precursor polypeptide, pol ...
. There have also been rare reports of scalp or beard hair spontaneously turning partially red, with no identified pathological cause.


Culture

In various times and cultures, red hair has been prized, feared, and ridiculed.


Media, fashion and art

Queen Elizabeth I of England was a redhead, and during the
Elizabethan era The Elizabethan era is the epoch in the Tudor period of the history of England during the reign of Queen Elizabeth I (1558–1603). Historians often depict it as the golden age in English history. The Roman symbol of Britannia (a female ...
in England, red hair was fashionable for women. In modern times, red hair is subject to fashion trends; celebrities such as
Nicole Kidman Nicole Mary Kidman (born 20 June 1967) is an Australian and American actress and producer. Known for Nicole Kidman on screen and stage, her work in film and television productions across many genres, she has consistently ranked among the world ...
, Alyson Hannigan,
Marcia Cross Marcia Anne Cross (born March 25, 1962) is an American actress. She acted in daytime soap operas such as ''The Edge of Night'', ''Another World (TV series), Another World'', and ''One Life to Live'' before moving to primetime television with a ...
, Christina Hendricks, Emma Stone and Geri Halliwell can boost sales of red hair dye. Sometimes, red hair darkens as people get older, becoming a more brownish color or losing some of its vividness. This leads some to associate red hair with youthfulness, a quality that is generally considered desirable. In several countries such as India, Iran, Bangladesh and Pakistan, henna and saffron are used on hair to give it a bright red appearance. Many painters have exhibited a fascination with red hair. The hair color "
Titian Tiziano Vecellio (; 27 August 1576), Latinized as Titianus, hence known in English as Titian ( ), was an Italian Renaissance painter, the most important artist of Renaissance Venetian painting. He was born in Pieve di Cadore, near Belluno. Ti ...
" takes its name from the artist
Titian Tiziano Vecellio (; 27 August 1576), Latinized as Titianus, hence known in English as Titian ( ), was an Italian Renaissance painter, the most important artist of Renaissance Venetian painting. He was born in Pieve di Cadore, near Belluno. Ti ...
, who often painted women with red hair. Early Renaissance artist
Sandro Botticelli Alessandro di Mariano di Vanni Filipepi ( – May 17, 1510), better known as Sandro Botticelli ( ; ) or simply known as Botticelli, was an Italian painter of the Early Renaissance. Botticelli's posthumous reputation suffered until the late 1 ...
's famous painting '' The Birth of Venus'' depicts the mythological goddess
Venus Venus is the second planet from the Sun. It is often called Earth's "twin" or "sister" planet for having almost the same size and mass, and the closest orbit to Earth's. While both are rocky planets, Venus has an atmosphere much thicker ...
as a redhead. Other painters notable for their redheads include the Pre-Raphaelites, Edmund Leighton, Modigliani, and Gustav Klimt. Sir Arthur Conan Doyle's
Sherlock Holmes Sherlock Holmes () is a Detective fiction, fictional detective created by British author Arthur Conan Doyle. Referring to himself as a "Private investigator, consulting detective" in his stories, Holmes is known for his proficiency with obser ...
story " The Red-Headed League" (1891) involves a man who is asked to become a member of a mysterious group of red-headed people. The 1943 film '' DuBarry Was a Lady'' featured red-heads
Lucille Ball Lucille Désirée Ball (August 6, 1911 – April 26, 1989) was an American actress, comedian, producer, and studio executive. She was recognized by ''Time (magazine), Time'' in 2020 as one of the most influential women of the 20th century for h ...
and
Red Skelton Richard Bernard Skelton (July 18, 1913September 17, 1997) was an American entertainer best known for his national old-time radio, radio and television shows between 1937 and 1971, especially as host of the television program ''The Red Skelto ...
in Technicolor. Notable comic book characters with red hair include Jean Grey, Red Sonja, Mystique (comics), Mystique, and Poison Ivy (character), Poison Ivy. A book of photographs of red haired people was published in 2020, ''Gingers'' by Kieran Dodds (2020).


Red hair festivals

There has been an annual Redhead Day festival in the Netherlands that attracts red-haired participants from around the world. The festival was held in Breda, a city in the south east of the Netherlands, prior to 2019, when it moved to Tilburg. It attracts participants from over 80 countries. The international event began in 2005, when Dutch painter Bart Rouwenhorst decided he wanted to paint 15 redheads. The Irish Redhead Convention, held in late August in County Cork since 2011, claims to be a global celebration and attracts people from several continents. The celebrations include crowning the ginger King and Queen, competitions for the best red eyebrows and most freckles per square inch, orchestral concerts and carrot throwing competitions. A smaller red-hair day festival is held since 2013 by the UK's Anti-Bullying Week, Anti-Bullying Alliance in London, with the aim of instilling pride in having red-hair. Since 2014, a red-hair event is held in Israel, at Gezer (kibbutz), Kibbutz Gezer (Carrot), for the local Israeli red hair community, including both Ashkenazi and Mizrahi Jews, Mizrahi red-heads. However, the number of attendees has to be restricted due to the risk of rocket attacks, leading to anger in the red-hair community.Finally, a Red Alert This Summer That (Most) Israelis Welcomed
Roy Arad, Haaretz.com, 30 August 2014.
The organizers state; "The event is a good thing for many redheads, who had been embarrassed about being redheads before." The first and only festival for red heads in the United States was launched in 2015. Held in Highwood, Illinois, Redhead Days draws participants from across the United States. A festival to celebrate the red-haired people is held annually in Izhevsk (Russia), the capital of Udmurtia, since 2004. MC1R Magazine is a publication for red-haired people worldwide, based in Hamburg, Germany.


Religious and mythological traditions

In ancient Egypt, red hair was associated with the deity Set (deity), Set, as well as Ramesses II. In the ''Iliad'', Achilles' hair is described as (), usually translated as blonde, or golden but sometimes as red or tawny. His son Neoptolemus also bears the name Pyrrhus, a possible reference to his own red hair. The Norse mythology, Norse god Thor is usually described as having red hair. The Hebrew word usually translated "ruddy" or "reddish-brown" (''admoni'' , from the root ''ADM'' , see also Adam and Edom) was used to describe both
Esau Esau is the elder son of Isaac in the Hebrew Bible. He is mentioned in the Book of Genesis and by the minor prophet, prophets Obadiah and Malachi. The story of Jacob and Esau reflects the historical relationship between Israel and Edom, aiming ...
and
David David (; , "beloved one") was a king of ancient Israel and Judah and the third king of the United Monarchy, according to the Hebrew Bible and Old Testament. The Tel Dan stele, an Aramaic-inscribed stone erected by a king of Aram-Dam ...
. Judas Iscariot is also represented with red hair in Spanish culture and in the works of William Shakespeare, reinforcing the negative stereotype.


The name "Rory"

The mainly masculine given name ''Rory'' – a name of Goidelic languages, Goidelic origin, which is an anglicisation of the /''Ruaidhrí/Ruaidhrígh/Raidhrígh'', and Manx language, Manx: ''Rauree'' which is common to the Irish people, Irish, Scottish people, Highland Scots and their diasporas for the given name "Rory". – means "red-haired king", from ''ruadh'' ("red-haired" or "rusty") and ''rígh'' ("king"). However, present bearers of the name are by no means all red-haired themselves.


Prejudice and discrimination against redheads


Beliefs concerning temperament

A common belief about redheads is that they have fiery tempers and sharp tongues. In ''Anne of Green Gables'', a character says of Anne Shirley, the redheaded heroine, that "her temper matches her hair", while in ''The Catcher in the Rye'', Holden Caulfield remarks that "People with red hair are supposed to get mad very easily, but Allie [his dead brother] never did, and he had very red hair." During the early stages of modern medicine, red hair was thought to be a sign of a wiktionary:sanguine#Adjective, sanguine Four temperaments, temperament. In the Indian medicinal practice of Ayurveda, redheads are seen as most likely to have a Humours (Ayurveda), Pitta temperament. Another belief is that redheads are highly sexed; for example, Jonathan Swift satirizes redhead stereotypes in part four of ''Gulliver's Travels'', "A Voyage to the Country of the Houyhnhnms," when he writes that: "It is observed that the red-haired of both sexes are more libidinous and mischievous than the rest, whom yet they much exceed in strength and activity." Swift goes on to write that "neither was the hair of this brute [a Yahoo (literature), Yahoo] of a red colour (which might have been some excuse for an appetite a little irregular) but black as a sloe". Such beliefs were given a veneer of scientific credibility in the 19th century by Cesare Lombroso and Guglielmo Ferrero. They concluded that red hair was associated with crimes of lust, and claimed that 48% of "criminal women" were redheads.


Medieval beliefs

Theophilus Presbyter describes how the blood of a red-haired young man is necessary to create gold from copper, in a mixture with the ashes of a basilisk. According to Montague Summers, red hair and green eyes were thought to be the sign of a witch, werewolf or vampire during the Middle Ages:


Medieval antisemitism

During the
Spanish Inquisition The Tribunal of the Holy Office of the Inquisition () was established in 1478 by the Catholic Monarchs of Spain, Catholic Monarchs, King Ferdinand II of Aragon and Queen Isabella I of Castile and lasted until 1834. It began toward the end of ...
, people of red hair were identified as Jewish and isolated for persecution. In medieval Italy and Spain, red hair was associated with the heretical nature of Jews and their rejection of Jesus, and thus Judas Iscariot was commonly depicted as red-haired in Italian and Spanish art. Writers from Shakespeare to Dickens would identify Jewish characters by giving them red hair, such as the villainous Jewish characters Shylock and Fagin. The antisemitic association persisted into modern times in Soviet Russia. The medieval prejudice against red-hair may have derived from the ancient biblical tradition, in relation to biblical figures such as
Esau Esau is the elder son of Isaac in the Hebrew Bible. He is mentioned in the Book of Genesis and by the minor prophet, prophets Obadiah and Malachi. The story of Jacob and Esau reflects the historical relationship between Israel and Edom, aiming ...
and King David. The ancient historian Josephus would mistranslate the Hebrew Torah to describe the more positive figure of King David as 'golden haired', in contrast to the negative figure of
Esau Esau is the elder son of Isaac in the Hebrew Bible. He is mentioned in the Book of Genesis and by the minor prophet, prophets Obadiah and Malachi. The story of Jacob and Esau reflects the historical relationship between Israel and Edom, aiming ...
, even though the original Hebrew Torah implies that both King David and Esau had 'fiery red hair'.


Modern-day discrimination

In his 1885 book ''I Say No'', Wilkie Collins wrote "The prejudice against habitual silence, among the lower order of the people, is almost as inveterate as the prejudice against red hair." In his 1895 memoir and history ''The Gurneys of Earlham'', Augustus John Cuthbert Hare described an incident of harassment: "The second son, John, was born in 1750. As a boy he had bright red hair, and it is amusingly recorded that one day in the streets of Norwich a number of boys followed him, pointing to his red locks and saying, "Look at that boy; he's got a bonfire on the top of his head," and that John Gurney was so disgusted that he went to a barber's, had his head shaved, and went home in a wig. He grew up, however, a remarkably attractive-looking young man." In British English, the word "ginger" is sometimes used to describe red-headed people (at times in an insulting manner), with terms such as "gingerphobia" and "gingerism" used by the British media. It is roughly the color of dried, powdered Ginger, ginger root. In Britain, redheads are also sometimes referred to disparagingly as "carrot tops" and "carrot heads" (the comedian "Carrot Top" uses this stage name). "Gingerism" has been compared to racism, although this is widely disputed, and bodies such as the UK Commission for Racial Equality do not monitor cases of discrimination and hate crimes against redheads. Nonetheless, individuals and families in Britain are targeted for harassment and violence because of their hair colour. In 2003, a 20-year-old was stabbed in the back for "being ginger". In 2007, a UK woman won an award from a tribunal after being sexually harassed and receiving abuse because of her red hair; in the same year, a family in Newcastle upon Tyne, was forced to move twice after being targeted for abuse and hate crimes on account of their red hair. In May 2009, a schoolboy committed suicide after being bullied for having red hair. In 2013, a fourteen-year-old boy in Lincoln, England, Lincoln had his right arm broken and his head stamped on by three men who attacked him "just because he had red hair"; the three men were subsequently jailed for a combined total of ten years and one month for the attack. This prejudice has been satirised on a number of TV shows. English comedian Catherine Tate (herself a redhead) appeared as a red-haired character in a running sketch of her series ''The Catherine Tate Show''. The sketch saw fictional character The Catherine Tate Show characters#Sandra Kemp, Sandra Kemp, who was forced to seek solace in a refuge for ginger people because she had been ostracised from society. The British comedy ''Bo' Selecta!'' (starring redhead Leigh Francis) featured a spoof documentary which involved a caricature of Mick Hucknall presenting a show in which celebrities (played by themselves) dyed their hair red for a day and went about daily life being insulted by people; Hucknall, who says that he has repeatedly faced prejudice or been described as ugly on account of his hair colour, argues that Gingerism should be described as a form of racism. Comedian Tim Minchin, himself a redhead, also covered the topic in his song "Prejudice". The pejorative use of the word "ginger" and related discrimination was used to illustrate a point about racism and prejudice in the "Ginger Kids", "Le Petit Tourette", "It's a Jersey Thing" and "Fatbeard" episodes of ''South Park''. Film and television programmes often portray school bullying, bullies as having red hair. However, children with red hair are often themselves targeted by bullies; "Somebody with ginger hair will stand out from the crowd," says anti-bullying expert Louise Burfitt-Dons. In Australian slang, redheads are often nicknamed "Blue" or "Bluey". More recently, they have been referred to as "rangas" (a word derived from the red-haired ape, the orangutan), sometimes with derogatory connotations. The word "rufus" (a variant of rufous, a reddish-brown color) has been used in both Australian and British slang to refer to red-headed people. In November 2008, social networking website Facebook received criticism after a "Kick a Ginger" group, which aimed to establish a "National Kick a Ginger Day" on 20 November, acquired almost 5,000 members. A 14-year-old boy from Vancouver who ran the Facebook group was subjected to an investigation by the Royal Canadian Mounted Police for possible hate crimes. In December 2009 British supermarket chain Tesco withdrew a Christmas card which had the image of a child with red hair sitting on the lap of Father Christmas, and the words: "''Santa loves all kids. Even ginger ones''" after customers complained the card was offensive. In October 2010, Harriet Harman, the former Equality Minister in the British government under Labour, faced accusations of prejudice after she described the red-haired Treasury secretary Danny Alexander as a "ginger rodent". Alexander responded to the insult by stating that he was "proud to be ginger". Harman was subsequently forced to apologise for the comment, after facing criticism for prejudice against a minority group. In September 2011, Cryos International, one of the world's largest sperm banks, announced that it would no longer accept donations from red-haired men due to low demand from women seeking artificial insemination.


Use of term in Singapore and Malaysia

The term ''ang mo'' ( zh, s=红毛, p=hóng máo, poj=âng-mo͘) in Hokkien dialect, Hokkien (Min Nan) Chinese, meaning "red-haired", is used in Malaysia and Singapore, although it refers to all white people, never exclusively people with red hair. The epithet is sometimes rendered as ''ang mo kui'' () meaning "red-haired devil", similar to the Cantonese term ''gweilo'' ("foreign devil"). Thus it is viewed as racist and derogatory by some people. Others, however, maintain it is acceptable. Despite this ambiguity, it is a widely used term. It appears, for instance, in Singaporean newspapers such as ''The Straits Times'', and in television programmes and films. The Chinese characters for ''ang mo'' are the same as those in the historical Japanese term ''Kōmō'' (), which was used during the Edo period (1603–1868) as an epithet for Dutch or Northern European people. It primarily referred to Netherlands, Dutch traders who were the only Europeans allowed to trade with Japan during ''Sakoku'', its 200-year period of isolation.See, for example, ; ; ; ; ; The historic fortress Fort Santo Domingo in Tamsui District, Tamsui, Taiwan was nicknamed in Taiwanese Hokkien, Taiwanese Hokkien zh, t=紅毛城, poj=Âng-mn̂g-siâⁿ, l=ang mo, Red-hair (ang mo) fort.


See also

* Blond hair * Black hair * Brown hair * Erythrism – in non-human animals * ''How to be a Redhead'' * List of people with red hair


Notes


References


Further reading

*


External links

{{Hair colors Red hair, Stereotypes Hair color