Paweł Kisielow (Polish: ; born 21 February 1945 in Gorlice, Poland) is a Polish biologist who specializes in immunology. He is best known for his research on

T cell T cells (also known as T lymphocytes) are an important part of the immune system and play a central role in the adaptive immune response. T cells can be distinguished from other lymphocytes by the presence of a T-cell receptor (TCR) on their cell ...

s. He is a corresponding member of the

Polish Academy of Sciences The Polish Academy of Sciences (, PAN) is a Polish state-sponsored institution of higher learning. Headquartered in Warsaw, it is responsible for spearheading the development of science across the country by a society of distinguished scholars a ...

and a member of the Polish Academy of Arts and Sciences.

Career

He graduated in

biology Biology is the scientific study of life and living organisms. It is a broad natural science that encompasses a wide range of fields and unifying principles that explain the structure, function, growth, History of life, origin, evolution, and ...

from the Adam Mickiewicz University in

Poznań Poznań ( ) is a city on the Warta, River Warta in west Poland, within the Greater Poland region. The city is an important cultural and business center and one of Poland's most populous regions with many regional customs such as Saint John's ...

and received a doctoral degree in 1971. He became a professor in 1987. He works at the Hirszfeld Institute of Immunology and Experimental Therapy of the

. In 1992, he received the Jurzykowski Prize conferred by the Alfred Jurzykowski Foundation in New York. In 1997, he was awarded the Körber European Science Prize jointly with Klaus Rajewsky and Harald von Boehmer for their work on mutant mouse models in clinical research. His scientific contributions have made significant progress towards better understanding the defense system leading to the development of treatments to support a weakened immune system, to combat

cancer Cancer is a group of diseases involving Cell growth#Disorders, abnormal cell growth with the potential to Invasion (cancer), invade or Metastasis, spread to other parts of the body. These contrast with benign tumors, which do not spread. Po ...

and to deal with autoimmune diseases. In 2003, he became the recipient of the

Prime Minister A prime minister or chief of cabinet is the head of the cabinet and the leader of the ministers in the executive branch of government, often in a parliamentary or semi-presidential system. A prime minister is not the head of state, but r ...

Award for his outstanding scientific output.

Selected publications

*''How does the immune system learn to distinguish between good and evil? The first definitive studies of T cell central tolerance and positive selection'' (2019) *''The evolutionary conservation of the bidirectional activity of the NWC gene promoter in jawed vertebrates and the domestication of the RAG transposon'' (with Lukasz Sniezewski, Sylwia Janik, Agnieszka Łaszkiewicz, Malgorzata Cebrat, 2017) *''Anti-GITR Antibody Treatment Increases TCR Repertoire Diversity of Regulatory but not Effector T Cells Engaged in the Immune Response Against B16 Melanoma'' (with Bozena Scirka, Edyta Anna Szurek, Maciej Pietrzak, Arkadiusz Miazek, 2017) *''Search for the Function of NWC, Third Gene Within RAG Locus: Generation and Characterization of NWC-Deficient Mice'' (with Monika Kasztura, Lukasz Sniezewski, Agnieszka Łaszkiewicz, 2015)

References

{{DEFAULTSORT:Baranowski, Bogdan 1945 births Living people Polish biologists Polish immunologists People from Gorlice Adam Mickiewicz University in Poznań alumni Members of the Polish Academy of Sciences

Career

Selected publications

See also

References