Kanamienamides is a complex

enol ether In organic chemistry an enol ether is an alkene with an alkoxy substituent. The general structure is R2C=CR-OR where R = H, alkyl or aryl. A common subfamily of enol ethers are vinyl ethers, with the formula ROCH=CH2. Important enol ethers include ...

containing enamide that is currently undergoing research in regards to its inhibitory activity towards cancer cells. The synthesis of kanamienamide consists of several chemical techniques, including CBS asymmetric reduction, Stork-Zhao- Wittig olefination, Cu-mediated

amide In organic chemistry, an amide, also known as an organic amide or a carboxamide, is a compound with the general formula , where R, R', and R″ represent organic groups or hydrogen atoms. The amide group is called a peptide bond when it is ...

coupling with

vinyl iodide In organic chemistry, a vinyl iodide (also known as an iodoalkene) functional group is an alkene with one or more iodide substituents. Vinyl iodides are versatile molecules that serve as important building blocks and precursors in organic synthesi ...

, Evans asymmetric

alkylation Alkylation is the transfer of an alkyl group from one molecule to another. The alkyl group may be transferred as an alkyl carbocation, a free radical, a carbanion, or a carbene (or their equivalents). Alkylating agents are reagents for effecting ...

, and

ring-closing metathesis Ring-closing metathesis (RCM) is a widely used variation of olefin metathesis in organic chemistry for the synthesis of various unsaturated rings via the intramolecular metathesis of two terminal alkenes, which forms the cycloalkene as the ''E-' ...

. Kanamienamide is a natural product found in '' Moorea bouillonii'' which is a cyanobacterium.

References

Heterocyclic compounds with 1 ring Nitrogen heterocycles Oxygen heterocycles Amides Methoxy compounds Lactones Lactams Eleven-membered rings {{heterocyclic-stub