The foramen ovale (Latin: oval window) is a hole in the posterior part of the

sphenoid bone The sphenoid bone is an unpaired bone of the neurocranium. It is situated in the middle of the skull towards the front, in front of the basilar part of occipital bone, basilar part of the occipital bone. The sphenoid bone is one of the seven bones ...

, posterolateral to the

foramen rotundum The foramen rotundum is a circular hole in the sphenoid bone of the skull. It connects the middle cranial fossa and the pterygopalatine fossa. It allows for the passage of the maxillary nerve (V2), a branch of the trigeminal nerve. Structure T ...

. It is one of the larger of the several holes (the

foramina In anatomy and osteology, a foramen (;Entry "foramen"
in

) in the skull. It transmits the

mandibular nerve In neuroanatomy, the mandibular nerve (V) is the largest of the three divisions of the trigeminal nerve, the fifth cranial nerve (CN V). Unlike the other divisions of the trigeminal nerve (ophthalmic nerve, maxillary nerve) which contain only aff ...

, a branch of the

trigeminal nerve In neuroanatomy, the trigeminal nerve ( lit. ''triplet'' nerve), also known as the fifth cranial nerve, cranial nerve V, or simply CN V, is a cranial nerve responsible for sensation in the face and motor functions such as biting and chewin ...

Structure

The

foramen In anatomy and osteology, a foramen (;Entry "foramen"
in

ovale is an opening in the greater wing of the

. The foramen ovale is one of two cranial foramina in the greater wing, the other being the

foramen spinosum The foramen spinosum is a hole located in the greater wing of the sphenoid. It is located posterolateral to the foramen ovale and anterior to the sphenoidal spine. It allows the passage of the middle meningeal artery, middle meningeal vein and ...

. The foramen ovale is posterolateral to the

and anteromedial to the

. Posterior and medial to the foramen is the opening for the

carotid canal The carotid canal is a passageway in the temporal bone of the skull through which the internal carotid artery enters the middle cranial fossa from the neck. Structure The carotid canal is located within the middle cranial fossa, at the petrous ...

Variation

Similar to other foramina, the foramen ovale differs in shape and size throughout the natural life. The earliest perfect ring-shaped formation of the foramen ovale was observed in the 7th fetal month and the latest in 3 years after birth, in a study using over 350 skulls.
In a study conducted on 100 skulls, the foramen ovale was divided into 2 or 3 components in 4.5% of the cases. The borders of the foramen in some skulls were also irregular and rough. This may suggest, based on radiological images, the presence of morbid changes, which might be the sole anatomical variation in the foramina ovalia of humans. In newborn, the foramen ovale is about 3.85 mm and in the adults about 7.2 mm in length. The average maximal length is about 7.48 mm and its average minimal length is 4.17 mm in the adult. The width extends from 1.81 mm in the newborn to 3.7 mm in adults.

Structures passing through

The following structures pass through foramen ovale: *

(a branch of the

). *

accessory meningeal artery The accessory meningeal artery (also accessory branch of middle meningeal artery, pterygomeningeal artery, small meningeal or parvidural branch) is a branch of the maxillary artery, sometimes derived from the middle meningeal artery. Course It ent ...

. *

lesser petrosal nerve The lesser petrosal nerve (also known as the small superficial petrosal nerve) is the general visceral efferent (GVE) component of the glossopharyngeal nerve (CN IX), carrying parasympathetic preganglionic fibers from the tympanic plexus to the p ...

(a branch of the

glossopharyngeal nerve The glossopharyngeal nerve (), also known as the ninth cranial nerve, cranial nerve IX, or simply CN IX, is a cranial nerve that exits the brainstem from the sides of the upper Medulla oblongata, medulla, just anterior (closer to the nose) to t ...

). * an

emissary vein The emissary veins connect the extracranial venous system with the intracranial venous sinuses. They connect the veins outside the cranium to the venous sinuses inside the cranium. They drain from the scalp, through the human skull, skull, into t ...

connecting the

cavernous sinus The cavernous sinus within the human head is one of the dural venous sinuses creating a cavity called the lateral sellar compartment bordered by the temporal bone of the skull and the sphenoid bone, lateral to the sella turcica. Structure The cave ...

with the

pterygoid plexus The pterygoid plexus (;Entry "pterygoid"
in

Clinical significance

The foramen ovale is used as the entry point into the skull when conducting a Percutaneous Rhizotomy using either radio-frequency ablation, balloon compression or glycerol injection. These are performed to treat

trigeminal neuralgia Trigeminal neuralgia (TN or TGN), also called Fothergill disease, tic douloureux, or trifacial neuralgia is a long-term pain disorder that affects the trigeminal nerve, the nerve responsible for sensation in the face and motor functions such as ...

. In the procedure, the electrode is introduced through the cheek of an anesthetized patient and radiologically guided into the foramen ovale, with the intention of partially or fully ablating one or more of the divisions (typically the Mandibular) to relieve pain. This entry point is also used to surgically place local electrodes directly on the surface of the mesial temporal lobe, in order to observe neural activity of patients with suspected focal epilepsy.

History

Etymology

The name "foramen ovale" comes from the

Latin Latin (, or , ) is a classical language belonging to the Italic branch of the Indo-European languages. Latin was originally a dialect spoken in the lower Tiber area (then known as Latium) around present-day Rome, but through the power of the ...

"oval hole / window".

References

External links

* * () *
Adult skull as seen from beneath at uiuc.edu
{{Authority control Foramina of the skull