Francesco I (25 March 1541 – 19 October 1587) was the second
Grand Duke of Tuscany
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, ruling from 1574 until his death in 1587. He was a member of the
House of Medici
The House of Medici ( , ; ) was an Italian banking family and political dynasty that first consolidated power in the Republic of Florence under Cosimo de' Medici and his grandson Lorenzo de' Medici, Lorenzo "the Magnificent" during the first h ...
.
Biography

Born in
Florence
Florence ( ; ) is the capital city of the Italy, Italian region of Tuscany. It is also the most populated city in Tuscany, with 362,353 inhabitants, and 989,460 in Metropolitan City of Florence, its metropolitan province as of 2025.
Florence ...
, Francesco was the son of
Cosimo I de' Medici, Grand Duke of Tuscany
Cosimo I de' Medici (12 June 1519 – 21 April 1574) was the second and last duke of Florence from 1537 until 1569, when he became the first grand duke of Tuscany, a title he held until his death. Cosimo I succeeded his cousin to the duchy. ...
, and
Eleanor of Toledo. He served as
regent
In a monarchy, a regent () is a person appointed to govern a state because the actual monarch is a minor, absent, incapacitated or unable to discharge their powers and duties, or the throne is vacant and a new monarch has not yet been dete ...
for his father Cosimo after he retired from his governing duties in 1564.
Marriage to Joanna of Austria
On 18 December 1565, Francesco married Archduchess
Joanna of Austria, youngest daughter of
Ferdinand I, Holy Roman Emperor
Ferdinand I (10 March 1503 – 25 July 1564) was Holy Roman Emperor from 1556, King of Bohemia, King of Hungary, Hungary, and List of rulers of Croatia, Croatia from 1526, and Archduke of Austria from 1521 until his death in 1564.Milan Kruhek ...
and his wife
Anne of Bohemia and Hungary
Anna of Bohemia and Hungary (23 July 1503 – 27 January 1547), sometimes known as Anna Jagellonica, was Queen of Germany, List of Bohemian consorts, Bohemia, and List of Hungarian consorts, Hungary and Archduchess of Austria as the wife o ...
. By all reports, it was not a happy marriage. Joanna was homesick for her native Austria, and Francesco was neither charming nor faithful. In 1578, Joanna died at the age of thirty-one, after falling down a flight of stairs while pregnant with their eighth child.
Bianca Cappello
Soon after Grand Duchess Joanna had died, Francesco went on to marry his Venetian mistress,
Bianca Cappello, after aptly disposing of her husband, a Florentine bureaucrat. Because of the quick remarriage and similar occurrences among the Medici (Francesco's younger brother Pietro had reportedly killed his wife), rumours spread that Francesco and Bianca had conspired to poison Joanna. Francesco reportedly built and decorated the
Villa di Pratolino for Bianca. She was, however, not always popular among Florentines. They had no legitimate children, but Bianca had borne him a son, Antonio (29 August 1576 – 2 May 1621), in his first wife's lifetime. Following the death of Francesco's legitimate son
Filippo in 1582, Antonio was proclaimed heir. Francesco also adopted Bianca's daughter by her first marriage, Pellegrina (1564–?).

Like his father, Francesco was often despotic, but while Cosimo had known how to maintain Florentine independence, Francesco acted more like a vassal of the Habsburgs of Austria and Spain. He continued the heavy taxation of his subjects to pay large sums to the emperor.
Francesco had an avid interest in manufacturing and sciences. He founded
porcelain
Porcelain (), also called china, is a ceramic material made by heating Industrial mineral, raw materials, generally including kaolinite, in a kiln to temperatures between . The greater strength and translucence of porcelain, relative to oth ...
and stoneware manufacture, but these did not thrive until after his death. He continued his father's patronage of the arts, supporting artists and building the Medici Theater as well as founding the
Accademia della Crusca
The (; ), generally abbreviated as La Crusca, is a Florence-based society of scholars of Italian linguistics and philology. It is one of the most important research institutions of the Italian language, as well as the oldest Academy#Linguisti ...
. Francesco was also passionately interested in chemistry and alchemy and spent many hours in his private laboratory and curio collection, the
Studiolo in the
Palazzo Vecchio
The ( "Old Palace") is the town hall of Florence, Italy. It overlooks the , which holds a copy of Michelangelo's ''David'' statue, and the gallery of statues in the adjacent Loggia dei Lanzi.
Originally called the ''Palazzo della Signoria'', a ...
, which held his collections of natural items and stones and allowed him to dabble in
chemistry
Chemistry is the scientific study of the properties and behavior of matter. It is a physical science within the natural sciences that studies the chemical elements that make up matter and chemical compound, compounds made of atoms, molecules a ...
and
alchemical schemes.
Francesco and Bianca died on 19 and 20 October, both at the Medici Villa in
Poggio a Caiano. Although the original death certificates mention malaria, it has been widely speculated that the couple was poisoned, possibly by Francesco's brother
Ferdinando. While some early forensic research supported the latter theory, forensic evidence from a study in 2010 found the parasite ''
Plasmodium falciparum
''Plasmodium falciparum'' is a Unicellular organism, unicellular protozoan parasite of humans and is the deadliest species of ''Plasmodium'' that causes malaria in humans. The parasite is transmitted through the bite of a female ''Anopheles'' mos ...
'', which causes
malaria
Malaria is a Mosquito-borne disease, mosquito-borne infectious disease that affects vertebrates and ''Anopheles'' mosquitoes. Human malaria causes Signs and symptoms, symptoms that typically include fever, Fatigue (medical), fatigue, vomitin ...
, in the skeletal remains of Francesco I, which strongly bolstered the infection theory and the credibility of the official documents. Francesco was succeeded by his younger brother Ferdinando.
In 1857, all members of the Medici family were exhumed and reburied in the place where they still lie today, the
Basilica of San Lorenzo in Florence. The painter
Giuseppe Moricci attended the ceremony and depicted Francesco with a facial droop, a right claw hand appearance, the right shoulder internally rotated, the right calf muscle wasted and a right clubfoot confirmed by orthopaedic footwear within the coffin. These are the signs of a right-sided stroke possibly within the
internal capsule
The internal capsule is a paired white matter structure, as a two-way nerve tract, tract, carrying afferent nerve fiber, ascending and efferent nerve fiber, descending axon, fibers, to and from the cerebral cortex. The internal capsule is situate ...
. The presence of the orthopaedic footwear suggests that this stroke happened significantly before his death. During life, in his official portraits, the grand duke was always depicted as being in perfect physical condition. The cause of his stroke is not known, but malaria is known to cause this condition.
There is a famous portrait of Francesco as a child by
Bronzino
Agnolo di Cosimo (; 17 November 150323 November 1572), usually known as Bronzino ( ) or Agnolo Bronzino, was an Italians, Italian Mannerism, Mannerist painter from Florence. His sobriquet, ''Bronzino'', may refer to his relatively dark skin or r ...
that hangs in the
Uffizi Gallery in
Florence
Florence ( ; ) is the capital city of the Italy, Italian region of Tuscany. It is also the most populated city in Tuscany, with 362,353 inhabitants, and 989,460 in Metropolitan City of Florence, its metropolitan province as of 2025.
Florence ...
. Francesco's marriage to Bianca and the couple's death was exploited by
Thomas Middleton
Thomas Middleton (baptised 18 April 1580 – July 1627; also spelt ''Midleton'') was an English Jacobean playwright and poet. He, with John Fletcher and Ben Jonson, was among the most successful and prolific of playwrights at work in the Jac ...
for his tragedy ''
Women Beware Women'', published in 1658.
Children
Francesco and Joanna had eight children:
#
Eleonora (28 February 1567 – 9 September 1611), who married
Vincenzo Gonzaga, Duke of Mantua (1562–1612)
# Romola (20 November 1568 – 2 December 1568)
#
Anna (31 December 1569 – 19 February 1584)
# Isabella (30 September 1571 – 8 August 1572)
# Lucrezia (7 November 1572 – 14 August 1574)
#
Marie (26 April 1575–3 July 1642), who became Queen of France by her marriage to
Henry IV in 1600
#
Filippo (20 May 1577 – 29 March 1582)
# a son, died in a miscarriage
In fiction
* Francesco de' Medici is a secondary character in
John Webster's
1612 play ''
The White Devil''.
References
Sources
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External links
*
"The Medici Archive Project" from the ''
Medici Archive Project''
"The Medici Archive Project Bio Page""Toledo-de' Medici, Leonor de (Eleonora)" from ''The Medici Archive Project''
"Osorio Pimentel, María" from ''The Medici Archive Project''
{{DEFAULTSORT:Medici, Francesco
1541 births
1587 deaths
16th-century Italian nobility
16th-century grand dukes of Tuscany
Tuscan nobility
Francesco 1
Italian Roman Catholics
Francesco
Francesco, the Italian language, Italian (and original) version of the personal name "Francis (given name), Francis", is one of the List of most popular given names, most common given name among males in Italy. Notable persons with that name inclu ...
Regents of Tuscany
Burials at San Lorenzo, Florence
Italian art patrons
Deaths from malaria