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Fasting is the abstention from eating and sometimes drinking. From a purely
physiological Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemica ...
context, "fasting" may refer to the
metabolic Metabolism (, from el, μεταβολή ''metabolē'', "change") is the set of life-sustaining chemical reactions in organisms. The three main functions of metabolism are: the conversion of the energy in food to energy available to run cel ...
status of a person who has not eaten overnight (see " Breakfast"), or to the metabolic state achieved after complete
digestion Digestion is the breakdown of large insoluble food molecules into small water-soluble food molecules so that they can be absorbed into the watery blood plasma. In certain organisms, these smaller substances are absorbed through the small intest ...
and absorption of a meal. Metabolic changes in the fasting state begin after absorption of a meal (typically 3–5 hours after eating). A diagnostic fast refers to prolonged fasting from 1 to 100 hours (depending on age) conducted under observation to facilitate the investigation of a health complication, usually
hypoglycemia Hypoglycemia, also called low blood sugar, is a fall in blood sugar to levels below normal, typically below 70 mg/dL (3.9 mmol/L). Whipple's triad is used to properly identify hypoglycemic episodes. It is defined as blood glucose be ...
. Many people may also fast as part of a medical procedure or a check-up, such as preceding a colonoscopy or surgery, or before certain medical tests. Intermittent fasting is a technique sometimes used for
weight loss Weight loss, in the context of medicine, health, or physical fitness, refers to a reduction of the total body mass, by a mean loss of fluid, body fat (adipose tissue), or lean mass (namely bone mineral deposits, muscle, tendon, and other con ...
that incorporates regular fasting into a person's dietary schedule. Fasting may also be part of a religious ritual, often associated with specifically scheduled fast days, as determined by the religion.


Health effects

Fasting may have different results on health in different circumstances. To understand whether loss of appetite ( anorexia) during illness was protective or detrimental, researchers in the laboratory of Ruslan Medzhitov at Yale School of Medicine gave
carbohydrate In organic chemistry, a carbohydrate () is a biomolecule consisting of carbon (C), hydrogen (H) and oxygen (O) atoms, usually with a hydrogen–oxygen atom ratio of 2:1 (as in water) and thus with the empirical formula (where ''m'' may or ...
to mice with a bacterial or viral illness, or deprived them of carbohydrate. They found that carbohydrate was detrimental to bacterial
sepsis Sepsis, formerly known as septicemia (septicaemia in British English) or blood poisoning, is a life-threatening condition that arises when the body's response to infection causes injury to its own tissues and organs. This initial stage is foll ...
. But with viral sepsis or
influenza Influenza, commonly known as "the flu", is an infectious disease caused by influenza viruses. Symptoms range from mild to severe and often include fever, runny nose, sore throat, muscle pain, headache, coughing, and fatigue. These symptom ...
, nutritional supplementation with carbohydrates was beneficial, decreasing mortality, whereas denying glucose to the mice, or blocking its metabolism, was lethal. The researchers put forth hypotheses to explain the findings and called for more research on humans to determine whether our bodies react similarly, depending on whether an illness is bacterial or viral. Alternate-day fasting (alternating between a 24-hour "fast day" when the person eats less than 25% of usual energy needs, followed by a 24-hour non-fasting "feast day" period) has been shown to improve cardiovascular and metabolic
biomarker In biomedical contexts, a biomarker, or biological marker, is a measurable indicator of some biological state or condition. Biomarkers are often measured and evaluated using blood, urine, or soft tissues to examine normal biological processes, p ...
s similarly to a calorie restriction diet in people who are overweight, obese or have metabolic syndrome. A 2021 review found that moderate alternate-day fasting for two to six months was associated with reductions of body weight, body mass index, and cardiometabolic risk factors in overweight or obese adults.


Medical application

Fasting is always practised prior to surgery or other procedures that require general anesthesia because of the risk of
pulmonary aspiration Pulmonary aspiration is the entry of material such as pharyngeal secretions, food or drink, or stomach contents from the oropharynx or gastrointestinal tract, into the larynx (voice box) and lower respiratory tract, the portions of the res ...
of gastric contents after induction of anesthesia (i.e., vomiting and inhaling the vomit, causing life-threatening aspiration pneumonia). Additionally, certain medical tests, such as cholesterol testing ( lipid panel) or certain
blood glucose Glycaemia, also known as blood sugar level, blood sugar concentration, or blood glucose level is the measure of glucose concentrated in the blood of humans or other animals. Approximately 4 grams of glucose, a simple sugar, is present in the bl ...
measurements require fasting for several hours so that a baseline can be established. In the case of a lipid panel, failure to fast for a full 12 hours (including vitamins) will guarantee an elevated triglyceride measurement.


Mental health

In one review, fasting improved alertness,
mood Mood may refer to: *Mood (psychology), a relatively long lasting emotional state Music *The Mood, a British pop band from 1981 to 1984 * Mood (band), hip hop artists * ''Mood'' (Jacquees album), 2016 * ''Moods'' (Barbara Mandrell album), 1978 ...
, and subjective feelings of well-being, possibly improving overall symptoms of depression, and boosting cognitive performance.


Weight loss

Intermittent fasting for periods shorter than 24 hours has been shown to be effective for
weight loss Weight loss, in the context of medicine, health, or physical fitness, refers to a reduction of the total body mass, by a mean loss of fluid, body fat (adipose tissue), or lean mass (namely bone mineral deposits, muscle, tendon, and other con ...
in obese and healthy adults and to maintain lean body mass.


Complications

In rare occurrences, dry fasting can lead to the potentially fatal refeeding syndrome upon reinstatement of food intake due to electrolyte imbalance.


Historical medical studies

Fasting was historically studied on population under famine and hunger strikes, which led to the alternative name of "starvation diet", as a diet with 0 calories intake per day.


Other effects

It has been argued that fasting makes one more appreciative of food, and possibly drink.


Political application

Fasting is often used to make a political statement, to
protest A protest (also called a demonstration, remonstration or remonstrance) is a public expression of objection, disapproval or dissent towards an idea or action, typically a political one. Protests can be thought of as acts of coopera ...
, or to bring awareness to a cause. A hunger strike is a method of non-violent resistance in which participants fast as an act of political protest, or to provoke feelings of guilt, or to achieve a goal such as a policy change. A ''spiritual fast'' incorporates personal spiritual beliefs with the desire to express personal principles, sometimes in the context of social injustice.Garcia, M. (2007) ''The Gospel of Cesar Chavez: My Faith in Action'' Sheed & Ward Publishing p. 103 The political leader Gandhi undertook several long fasts as political and social protests. Gandhi's fasts had a significant impact on the
British Raj The British Raj (; from Hindi language, Hindi ''rāj'': kingdom, realm, state, or empire) was the rule of the British The Crown, Crown on the Indian subcontinent; * * it is also called Crown rule in India, * * * * or Direct rule in India, * Q ...
and the Indian population generally. In Northern Ireland in 1981, a prisoner, Bobby Sands, was part of the 1981 Irish hunger strike, protesting for better rights in prison. Sands had just been elected to the British Parliament and died after 66 days of not eating. 100,000 people attended his funeral, and the strike ended only after nine other men died. In all, ten men survived without food for 46 to 73 days. César Chávez undertook several spiritual fasts, including a 25-day fast in 1968 promoting the principle of nonviolence and a fast of 'thanksgiving and hope' to prepare for pre-arranged civil disobedience by farm workers.Shaw, R. (2008)''Beyond the Fields: Cesar Chavez, the UFW, and the struggle for justice in the 21st century'' University of California Press, p.92 Chávez regarded a spiritual fast as "a personal spiritual transformation". Other progressive campaigns have adopted the tactic.


Religious views

Fasting is practiced in various religions. Examples include Lent in
Christianity Christianity is an Abrahamic monotheistic religion based on the life and teachings of Jesus of Nazareth Jesus, likely from he, יֵשׁוּעַ, translit=Yēšūaʿ, label=Hebrew/Aramaic ( AD 30 or 33), also referred to as Jesu ...
; Yom Kippur, Tisha B'av, Fast of Esther, Tzom Gedalia, the Seventeenth of Tamuz, and the Tenth of Tevet in
Judaism Judaism ( he, ''Yahăḏūṯ'') is an Abrahamic, monotheistic, and ethnic religion comprising the collective religious, cultural, and legal tradition and civilization of the Jewish people. It has its roots as an organized religion in the ...
.
Muslims Muslims ( ar, المسلمون, , ) are people who adhere to Islam, a monotheistic religion belonging to the Abrahamic tradition. They consider the Quran, the foundational religious text of Islam, to be the verbatim word of the God of Abra ...
fast during the month of Ramadan each year. The fast includes refraining from consuming any food or liquid from sun up until sundown. Details of fasting practices differ. Eastern Orthodox Christians fast during specified fasting seasons of the year, which include not only the better-known Great Lent, but also fasts on every Wednesday and Friday (except on special holidays), together with extended fasting periods before Christmas (the Nativity Fast), after Easter (the Apostles Fast) and in early August (the
Dormition Fast The Dormition of the Mother of God is a Great Feast of the Eastern Orthodox, Oriental Orthodox, and Eastern Catholic Churches (except the East Syriac churches). It celebrates the "falling asleep" (death) of Mary the ''Theotokos'' ("Mother ...
). Members of the Church of Jesus Christ of Latter-day Saints (
Mormon Mormons are a religious and cultural group related to Mormonism, the principal branch of the Latter Day Saint movement started by Joseph Smith in upstate New York during the 1820s. After Smith's death in 1844, the movement split into seve ...
s) generally abstain from food and drink for two consecutive meals in a 24-hour period on the first Sunday of each month.https://www.churchofjesuschrist.org/bc/content/ldsorg/topics/fasting-and-fast-offerings/PD60001350_TMP_2016%20LeadMtg_The%20Law%20of%20the%20Fast_9-15-16%20KW.pdf Like Muslims, they refrain from all drinking and eating unless they are children or are physically unable to fast. Fasting is also a feature of
ascetic Asceticism (; from the el, ἄσκησις, áskesis, exercise', 'training) is a lifestyle characterized by abstinence from sensual pleasures, often for the purpose of pursuing spiritual goals. Ascetics may withdraw from the world for their p ...
traditions in religions such as <