2,6-Dichloropyridine is a
chloropyridine Chloropyridines are a group of aryl chlorides consisting of a pyridine ring with chlorine atoms as substituents.
This may refer to:
* 2-Chloropyridine
*3-Chloropyridine
* 4-Chloropyridine
* 2,6-Dichloropyridine
Production
Direct halogenation of ...
with the formula C
5H
3Cl
2N. A white solid, it is one of six isomers of
dichloropyridine Dichloropyridines are organic compounds with the formula , consisting of a pyridine ring substituted with two chlorides. Six isomers are known. They are white or colorless, most are solids at room temperature.
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, + Isomers of ...
. It serves as a precursor to the antibiotic
enoxacin
EnoxacinEnoxacin is sold under the following trade names: Almitil, Bactidan, Bactidron, Comprecin, Enoksetin, Enoxen, Enroxil, Enoxin, Enoxor, Flumark, Penetrex, Gyramid, Vinone. is an oral broad-spectrum fluoroquinolone antibacterial agent used ...
,
as well as the drug and
anpirtoline
Anpirtoline (chemical formula C10H13ClN2S) is a synthetic chemical compound used as a 5-HT1B receptor agonist as well as a 5-HT3 receptor antagonist, causing a decrease in serotonin synthesis and a reduction in aggressive behavior. Anpirtoline h ...
and the antifungal
liranaftate
Liranaftate (trade name Zefnart) is a topical antifungal drug. It is used as a 2% cream used to treat tinea pedis (athlete's foot), tinea corporis (ringworm), and tinea cruris (jock itch). It was approved for use in Japan in August 2000.
L ...
.
Synthesis
2,6-Dichoropyridine is produced by reaction of pyridine with chlorine.
2-Chloropyridine is an intermediate.
[
]
Toxicity
The is 115 mg/kg (oral, mice).[
]
References
Chloropyridines
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