Øjvind Winge
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Øjvind Winge (19 May 1886 – 5 April 1964) was a Danish
biologist A biologist is a scientist who conducts research in biology. Biologists are interested in studying life on Earth, whether it is an individual Cell (biology), cell, a multicellular organism, or a Community (ecology), community of Biological inter ...
and a pioneer in
yeast Yeasts are eukaryotic, single-celled microorganisms classified as members of the fungus kingdom (biology), kingdom. The first yeast originated hundreds of millions of years ago, and at least 1,500 species are currently recognized. They are est ...
genetics.


Education

Winge was born in the city of
Aarhus Aarhus (, , ; officially spelled Ã…rhus from 1948 until 1 January 2011) is the second-largest city in Denmark and the seat of Aarhus municipality, Aarhus Municipality. It is located on the eastern shore of Jutland in the Kattegat sea and app ...
in
Jutland Jutland (; , ''Jyske Halvø'' or ''Cimbriske Halvø''; , ''Kimbrische Halbinsel'' or ''Jütische Halbinsel'') is a peninsula of Northern Europe that forms the continental portion of Denmark and part of northern Germany (Schleswig-Holstein). It ...
, the mainland of Denmark. After completing secondary school he travelled to the
University of Copenhagen The University of Copenhagen (, KU) is a public university, public research university in Copenhagen, Copenhagen, Denmark. Founded in 1479, the University of Copenhagen is the second-oldest university in Scandinavia, after Uppsala University. ...
to study law but found himself more suited to the
biological science Biology is the scientific study of life and living organisms. It is a broad natural science that encompasses a wide range of fields and unifying principles that explain the structure, function, growth, origin, evolution, and distribution of ...
s into which he transferred. He graduated with a master's degree in the year 1910. From Copenhagen he travelled to
Stockholm Stockholm (; ) is the Capital city, capital and List of urban areas in Sweden by population, most populous city of Sweden, as well as the List of urban areas in the Nordic countries, largest urban area in the Nordic countries. Approximately ...
,
Paris Paris () is the Capital city, capital and List of communes in France with over 20,000 inhabitants, largest city of France. With an estimated population of 2,048,472 residents in January 2025 in an area of more than , Paris is the List of ci ...
and
Chicago Chicago is the List of municipalities in Illinois, most populous city in the U.S. state of Illinois and in the Midwestern United States. With a population of 2,746,388, as of the 2020 United States census, 2020 census, it is the List of Unite ...
, studying mainly chromosomal
cytology Cell biology (also cellular biology or cytology) is a branch of biology that studies the structure, function, and behavior of cells. All living organisms are made of cells. A cell is the basic unit of life that is responsible for the living an ...
before finally returning to the University of Copenhagen to do a doctoral thesis entitled ''The Chromosomes: Their Numbers and General Importance''. In 1910 Winge was appointed chair of genetics at the
Royal Veterinary and Agricultural University The Royal Veterinary and Agricultural University (, abbr. KVL, , abbr. RVA) was a veterinary and agricultural science university in Denmark. It was founded in 1856 and operated until 2007, when it became a part of the University of Copenhagen. It ...
, Copenhagen, where amongst other works he wrote ''The Textbook in Genetics'', published in 1928.


Career

In 1933 Winge was offered and accepted the position of Director of the Physiology Department in the
Carlsberg Laboratory The Carlsberg Research Laboratory is a private scientific research center in Copenhagen, Denmark under the Carlsberg Foundation. It was founded in 1875 by J. C. Jacobsen, the founder of the Carlsberg brewery, with the purpose of advancing bioche ...
, Copenhagen. Here he dedicated his research to the 3 principal lifeforms of interest to his benefactors;
hops Hops are the flowers (also called seed cones or strobiles) of the hop plant ''Humulus lupulus'', a member of the Cannabaceae family of flowering plants. They are used primarily as a bittering, flavouring, and stability agent in beer, to whic ...
,
barley Barley (), a member of the grass family, is a major cereal grain grown in temperate climates globally. It was one of the first cultivated grains; it was domesticated in the Fertile Crescent around 9000 BC, giving it nonshattering spikele ...
and
yeast Yeasts are eukaryotic, single-celled microorganisms classified as members of the fungus kingdom (biology), kingdom. The first yeast originated hundreds of millions of years ago, and at least 1,500 species are currently recognized. They are est ...
, although his studies became increasingly dedicated to yeast. He developed and used techniques to achieve the micromanipulation of single yeast cells and
spore In biology, a spore is a unit of sexual reproduction, sexual (in fungi) or asexual reproduction that may be adapted for biological dispersal, dispersal and for survival, often for extended periods of time, in unfavourable conditions. Spores fo ...
s in order to investigate them on a genetic level. He found that yeast spores are
haploid Ploidy () is the number of complete sets of chromosomes in a cell (biology), cell, and hence the number of possible alleles for Autosome, autosomal and Pseudoautosomal region, pseudoautosomal genes. Here ''sets of chromosomes'' refers to the num ...
, and
diploid Ploidy () is the number of complete sets of chromosomes in a cell, and hence the number of possible alleles for autosomal and pseudoautosomal genes. Here ''sets of chromosomes'' refers to the number of maternal and paternal chromosome copies, ...
cells occur as a result of conjugation of two haploid cells or self-diploidisation. This was important as it revealed that the species exhibits alternation and that strains can be genetically manipulated by specific mating. Winge also demonstrated that the traits of the organisms were mainly governed by simple Mendelian rules. He continued his research and his lab produced a steady output of genetics papers until 1961. Winge's work was of critical importance to the basic formation of early
genetic engineering Genetic engineering, also called genetic modification or genetic manipulation, is the modification and manipulation of an organism's genes using technology. It is a set of Genetic engineering techniques, technologies used to change the genet ...
and
biotechnology Biotechnology is a multidisciplinary field that involves the integration of natural sciences and Engineering Science, engineering sciences in order to achieve the application of organisms and parts thereof for products and services. Specialists ...
. He helped to establish a firm basis for what have now developed into important and lucrative scientific fields. For this reason he is often attributed the title of 'The Father of Yeast Genetics'.


Winge's 1917 hypothesis

In his 1917 doctoral thesis ''The Chromosomes: Their Numbers and General Importance'', Winge presented his hypothesis of plant hybridization, which has motivated much research.


Awards and honours

Winge was elected foreign member of the
Royal Society The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, re ...
in 1947.


Botanical abbreviation


Selected bibliography

* Ferdinandsen, C. & Winge, Ø. (1910) Fungi from Professor Warming's expedition to
Venezuela Venezuela, officially the Bolivarian Republic of Venezuela, is a country on the northern coast of South America, consisting of a continental landmass and many Federal Dependencies of Venezuela, islands and islets in the Caribbean Sea. It com ...
and the
West Indies The West Indies is an island subregion of the Americas, surrounded by the Atlantic Ocean, North Atlantic Ocean and the Caribbean Sea, which comprises 13 independent island country, island countries and 19 dependent territory, dependencies in thr ...
. Botanisk Tidsskrift, 30, 211-. * Ferdinandsen, C. & Winge, Ø. (1914) Ostenfeldiella - a new genus of Plasmodiophoraceae. ''Annals of Botany'', 28, 643-649. Named for Carl Hansen Ostenfeld. * Winge Ø. (1914) Investigations on hops ( Humulus lupulus, L.). III. The pollination and fertilization process in Humulus lupulus L. and H. japonicus Sieb. et. Zucc. Comptes Rendus des Travaux du Laboratoire Carlsberg, 11, 1-46. * Winge, Ø. (1917) The chromosomes: their numbers and general importance. Comptes Rendus des Travaux du Laboratoire Carlsberg, 13, 131-275.
Doctoral thesis A thesis (: theses), or dissertation (abbreviated diss.), is a document submitted in support of candidature for an academic degree or professional qualification presenting the author's research and findings.International Standard ISO 7144: D ...
. * Winge, Ø. (1928) Textbook in Genetics (Danish title: ). 2nd edn. 1937; 3rd end. 1945. København. * Winge Ø. (1931) X- and Y-linked inheritance in Melandrium. Hereditas, 15, 127-165. * Winge, Ø. (1935) On haplophase and diplophase of some
Saccharomycetes Saccharomycetes belongs to the Ascomycota division of the kingdom Fungi. It is the only class in the subdivision Saccharomycotina, the budding yeast Yeasts are eukaryotic, single-celled microorganisms classified as members of the fungus kin ...
. Comptes Rendus des Travaux du Laboratoire Carlsberg. Série Physiologique, 21, 77-111. * Winge, Ø. (1950) Inheritance in dogs: with special reference to hunting breeds. Ithaca, New York. 153 p.


References

{{DEFAULTSORT:Winge, Ojvind 1886 births 1964 deaths Danish mycologists Danish geneticists University of Copenhagen alumni Carlsberg Laboratory staff Foreign members of the Royal Society Foreign associates of the National Academy of Sciences 20th-century Danish biologists