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Carlsberg Laboratory
The Carlsberg Research Laboratory is a private scientific research center in Copenhagen, Denmark under the Carlsberg Group. It was founded in 1875 by J. C. Jacobsen, the founder of the Carlsberg brewery, with the purpose of advancing biochemical knowledge, especially relating to brewing. It featured a Department of Chemistry and a Department of Physiology. In 1972, the laboratory was renamed the Carlsberg Research Center and was transferred to the brewery. Overview The Carlsberg Laboratory was known for isolating ''Saccharomyces carlsbergensis'', the species of yeast responsible for lager fermentation, as well as introducing the concept of pH in acid-base chemistry. The Danish chemist Søren Peder Lauritz Sørensen introduced the concept of pH, a scale for measuring acidity and basicity of substances. While working at the Carlsberg Laboratory, he studied the effect of ion concentration on proteins, and understood the concentration of hydrogen ions was particularly i ...
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Basicity
In chemistry, there are three definitions in common use of the word base, known as Arrhenius bases, Brønsted bases, and Lewis bases. All definitions agree that bases are substances that react with acids, as originally proposed by G.-F. Rouelle in the mid-18th century. In 1884, Svante Arrhenius proposed that a base is a substance which dissociates in aqueous solution to form Hydroxide ions OH−. These ions can react with hydrogen ions (H+ according to Arrhenius) from the dissociation of acids to form water in an acid–base reaction. A base was therefore a metal hydroxide such as NaOH or Ca(OH)2. Such aqueous hydroxide solutions were also described by certain characteristic properties. They are slippery to the touch, can taste bitter and change the color of pH indicators (e.g., turn red litmus paper blue). In water, by altering the autoionization equilibrium, bases yield solutions in which the hydrogen ion activity is lower than it is in pure water, i.e., the wat ...
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Jens Ø
Jens may refer to: * Jens (given name), a list of people with the name * Jens (surname), a list of people * Jens, Switzerland, a municipality * 1719 Jens 1719 Jens ( ''prov. designation'': ) is a background asteroid from the central region of the asteroid belt, approximately 19 kilometers in diameter. It was discovered on 17 February 1950, by German astronomer Karl Reinmuth at Heidelberg Observator ..., an asteroid See also * Jensen (other) * Jenssi {{disambiguation ...
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Klaus Bock
Klaus is a German, Dutch and Scandinavian given name and surname. It originated as a short form of Nikolaus, a German form of the Greek given name Nicholas. Notable persons whose family name is Klaus *Billy Klaus (1928–2006), American baseball player *Chris Klaus (born 1973), American entrepreneur * Frank Klaus (1887–1948), German-American boxer, 1913 Middleweight Champion * Fred Klaus (born 1967), German footballer *Josef Klaus (1910–2001), Chancellor of Austria 1966–1970 * Karl Ernst Claus (1796–1864), Russian chemist * Václav Klaus (born 1941), Czech politician, former President of the Czech Republic * Walter K. Klaus (1912–2012), American politician and farmer Notable persons whose given name is Klaus * Brother Klaus, Swiss patron saint * Klaus Augenthaler (born 1957), German football player and manager * Klaus Badelt (born 1967), German composer * Klaus Barbie (1913–1991), German SS-Hauptsturmführer and Holocaust Perpetrator * Klaus Bargsten (1911–2 ...
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Martin Ottesen
Martin may refer to: Places * Martin City (other) * Martin County (other) * Martin Township (other) Antarctica * Martin Peninsula, Marie Byrd Land * Port Martin, Adelie Land * Point Martin, South Orkney Islands Australia * Martin, Western Australia * Martin Place, Sydney Caribbean * Martin, Saint-Jean-du-Sud, Haiti, a village in the Sud Department of Haiti Europe * Martin, Croatia, a village in Slavonia, Croatia * Martin, Slovakia, a city * Martín del Río, Aragón, Spain * Martin (Val Poschiavo), Switzerland England * Martin, Hampshire * Martin, Kent * Martin, East Lindsey, Lincolnshire, hamlet and former parish in East Lindsey district * Martin, North Kesteven, village and parish in Lincolnshire in North Kesteven district * Martin Hussingtree, Worcestershire * Martin Mere, a lake in Lancashire ** WWT Martin Mere, a wetland nature reserve that includes the lake and surrounding areas * Martin Mill, Kent North America Canada * Rur ...
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Kaj Ulrik Linderstrøm-Lang
Kaj Ulrik Linderstrøm-Lang (29 November 1896 – 25 May 1959) was a Danish protein scientist, who was the director of the Carlsberg Laboratory from 1939 until his death. His most notable scientific contributions were the development of sundry physical techniques to study protein structure and function (especially hydrogen–deuterium exchange), and his definitions of protein primary, secondary, tertiary and quaternary structure. Linderstrøm-Lang devoted himself unstintingly to protein science and trained a whole generation of eminent protein scientists, Linderstrøm-Lang maintained a fun atmosphere in his laboratory and a happy spirit that expressed itself in wonderful Christmas parties and frequent trips to the Tivoli amusement park in Copenhagen. Linderstrøm-Lang was also a writer, musician and story-teller, and was active in the resistance movement against the Nazi occupation of Denmark. Research and career Early work Linderstrøm-Lang began as a physicist. Only a ye ...
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Johan Kjeldahl
Johan Gustav Christoffer Thorsager Kjeldahl ( 16 August 1849 – 18 July 1900), was a Danish chemist who developed a method for determining the amount of nitrogen in certain organic compounds using a laboratory technique which was named the Kjeldahl method after him. Professional life Kjeldahl worked in Copenhagen at the Carlsberg Laboratory, associated with Carlsberg Brewery, where he was head of the ''Chemistry department'' from 1876 to 1900. He was given the job to determine the amount of protein in the grain used in the malt industry. Less protein meant more beer. Kjeldahl found the answer was in developing a technique to determine nitrogen with accuracy but existing methods in analytical chemistry related to proteins and biochemistry at the time were far from accurate. Kjeldahl method In order to solve the problem of determining accurate nitrogen content in a sample, Kjeldahl developed a method which involves a two-step reaction: a distillation and a back titration. H ...
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PH Scale
In chemistry, pH (), historically denoting "potential of hydrogen" (or "power of hydrogen"), is a scale used to specify the acidity or basicity of an aqueous solution. Acidic solutions (solutions with higher concentrations of ions) are measured to have lower pH values than basic or alkaline solutions. The pH scale is logarithmic and inversely indicates the concentration of hydrogen ions in the solution.Bates, Roger G. ''Determination of pH: theory and practice''. Wiley, 1973. :\ce = - \log(a_\ce) = -\log( ce\ce M) where M = mol dm−3. At 25 °C (77 °F), solutions with a pH less than 7 are acidic, and solutions with a pH greater than 7 are basic. Solutions with a pH of 7 at this temperature are neutral (i.e. have the same concentration of H+ ions as OH− ions, i.e. pure water). The neutral value of the pH depends on the temperaturebeing lower than 7 if the temperature increases above 25 °C. The pH value can be less than 0 for very concentrated strong acids, ...
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Logarithmic Scale
A logarithmic scale (or log scale) is a way of displaying numerical data over a very wide range of values in a compact way—typically the largest numbers in the data are hundreds or even thousands of times larger than the smallest numbers. Such a scale is nonlinear: the numbers 10 and 20, and 60 and 70, are not the same distance apart on a log scale. Rather, the numbers 10 and 100, and 60 and 600 are equally spaced. Thus moving a unit of distance along the scale means the number has been ''multiplied'' by 10 (or some other fixed factor). Often exponential growth curves are displayed on a log scale, otherwise they would increase too quickly to fit within a small graph. Another way to think about it is that the ''number of digits'' of the data grows at a constant rate. For example, the numbers 10, 100, 1000, and 10000 are equally spaced on a log scale, because their numbers of digits is going up by 1 each time: 2, 3, 4, and 5 digits. In this way, adding two digits ''multiplies'' the ...
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Solution (chemistry)
In chemistry, a solution is a special type of homogeneous mixture composed of two or more substances. In such a mixture, a solute is a substance dissolved in another substance, known as a solvent. If the attractive forces between the solvent and solute particles are greater than the attractive forces holding the solute particles together, the solvent particles pull the solute particles apart and surround them. These surrounded solute particles then move away from the solid solute and out into the solution. The mixing process of a solution happens at a scale where the effects of chemical polarity are involved, resulting in interactions that are specific to solvation. The solution usually has the state of the solvent when the solvent is the larger fraction of the mixture, as is commonly the case. One important parameter of a solution is the concentration, which is a measure of the amount of solute in a given amount of solution or solvent. The term " aqueous solution" is used ...
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Hydronium Ion
In chemistry, hydronium (hydroxonium in traditional British English) is the common name for the aqueous cation , the type of oxonium ion produced by protonation of water. It is often viewed as the positive ion present when an Arrhenius acid is dissolved in water, as Arrhenius acid molecules in solution give up a proton (a positive hydrogen ion, ) to the surrounding water molecules (). In fact, acids must be surrounded by more than a single water molecule in order to ionize, yielding aqueous and conjugate base. Three main structures for the aqueous proton have garnered experimental support: The Eigen cation, which is a tetrahydrate, H3O+(H2O)3; the Zundel cation, which is a symmetric dihydrate, H+(H2O)2; and the Stoyanov cation, an expanded Zundel cation, which is a hexahydrate: H+(H2O)2(H2O)4. Spectroscopic evidence from well-defined IR spectra overwhelmingly supports the Stoyanov cation as the predominant form. For this reason, it has been suggested that wherever possi ...
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