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Portal Vein
The portal vein or hepatic portal vein (HPV) is a blood vessel that carries blood from the gastrointestinal tract, gallbladder, pancreas and spleen to the liver. This blood contains nutrients and toxins extracted from digested contents. Approximately 75% of total liver blood flow is through the portal vein, with the remainder coming from the hepatic artery proper. The blood leaves the liver to the heart in the hepatic veins. The portal vein is not a true vein, because it conducts blood to capillary beds in the liver and not directly to the heart. It is a major component of the hepatic portal system, one of three portal venous systems in the human body; the others being the hypophyseal portal system, hypophyseal and Renal portal system, renal portal systems. The portal vein is usually formed by the confluence of the superior mesenteric vein, superior mesenteric, splenic veins, inferior mesenteric vein, inferior mesenteric, left gastric vein, left, right gastric veins and the pancr ...
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Superior Mesenteric Vein
In human anatomy, the superior mesenteric vein (SMV) is a blood vessel that drains blood from the small intestine (jejunum and ileum). Behind the neck of the pancreas, the superior mesenteric vein combines with the splenic vein to form the portal vein that carries blood to the liver. The superior mesenteric vein lies to the right of the similarly named artery, the superior mesenteric artery, which originates from the abdominal aorta. Structure Tributaries of the superior mesenteric vein drain the small intestine, large intestine, stomach, pancreas and vermiform appendix, appendix and include: * Right gastro-omental vein (also known as the right gastro-epiploic vein) * inferior pancreaticoduodenal veins * veins from jejunum * veins from ileum * middle colic vein – drains the transverse colon * right colic vein – drains the ascending colon * ileocolic vein The superior mesenteric vein combines with the splenic vein to form the portal vein. Clinical significance Thrombosis of ...
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Hepatic Artery Proper
The hepatic artery proper (also proper hepatic artery) is the artery that supplies the liver and gallbladder. It raises from the common hepatic artery, a branch of the celiac artery. Structure The hepatic artery proper arises from the common hepatic artery and runs alongside the portal vein and the common bile duct to form the portal triad. A branch of the common hepatic arterythe gastroduodenal artery gives off the small supraduodenal artery to the duodenal bulb. Then the right gastric artery comes off and runs to the left along the lesser curvature of the stomach to meet the left gastric artery, which is a branch of the celiac trunk. It subsequently bifurcates into the right and left hepatic arteries. Variant anatomy Of note, the right and left hepatic arteries may demonstrate variant anatomy. A misplaced right hepatic artery may arise from the superior mesenteric artery (SMA) and a misplaced left hepatic artery may arise from the left gastric artery. The cystic artery g ...
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Abdominal Obesity
Abdominal obesity, also known as central obesity and truncal obesity, is the human condition of an excessive concentration of visceral fat around the stomach and abdomen to such an extent that it is likely to harm its bearer's health. Abdominal obesity has been strongly linked to cardiovascular disease, Alzheimer's disease, and other metabolic and vascular diseases. Visceral fat, central abdominal fat, and waist circumference show a strong association with type 2 diabetes. Visceral fat, also known as organ fat or ''intra-abdominal fat'', is located inside the peritoneal cavity, packed in between internal organs and torso, as opposed to subcutaneous fat, which is found underneath the skin, and intramuscular fat, which is found interspersed in skeletal muscle. Visceral fat is composed of several adipose depots including mesenteric, epididymal white adipose tissue (EWAT), and perirenal fat. An excess of adipose visceral fat is known as central obesity, the "pot belly" or " ...
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Cirrhosis
Cirrhosis, also known as liver cirrhosis or hepatic cirrhosis, chronic liver failure or chronic hepatic failure and end-stage liver disease, is a chronic condition of the liver in which the normal functioning tissue, or parenchyma, is replaced with scar tissue (fibrosis) and regenerative nodule (medicine), nodules as a result of chronic liver disease. Damage to the liver leads to repair of liver tissue and subsequent formation of scar tissue. Over time, scar tissue and nodules of regenerating hepatocytes can replace the parenchyma, causing increased resistance to blood flow in the liver's capillaries—the hepatic sinusoids—and consequently portal hypertension, as well as impairment in other aspects of liver function. The disease typically develops slowly over months or years. Stages include compensated cirrhosis and decompensated cirrhosis. Early symptoms may include Fatigue (medicine), tiredness, Asthenia, weakness, Anorexia (symptom), loss of appetite, weight loss, unexpla ...
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Portal Hypertension
Portal hypertension is defined as increased portal venous pressure, with a hepatic venous pressure gradient greater than 5 mmHg. Normal portal pressure is 1–4 mmHg; clinically insignificant portal hypertension is present at portal pressures 5–9 mmHg; clinically significant portal hypertension is present at portal pressures greater than 10 mmHg. The portal vein and its branches supply most of the blood and nutrients from the intestine to the liver. Cirrhosis (a form of chronic liver failure) is the most common cause of portal hypertension; other, less frequent causes are therefore grouped as non-cirrhotic portal hypertension. The signs and symptoms of both cirrhotic and non-cirrhotic portal hypertension are often similar depending on cause, with patients presenting with abdominal swelling due to ascites, vomiting of blood, and lab abnormalities such as elevated liver enzymes or low platelet counts. Treatment is directed towards decreasing portal hypertension itself or in ...
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Blood Pressure
Blood pressure (BP) is the pressure of Circulatory system, circulating blood against the walls of blood vessels. Most of this pressure results from the heart pumping blood through the circulatory system. When used without qualification, the term "blood pressure" refers to the pressure in a brachial artery, where it is most commonly measured. Blood pressure is usually expressed in terms of the systolic pressure (maximum pressure during one Cardiac cycle, heartbeat) over diastolic pressure (minimum pressure between two heartbeats) in the cardiac cycle. It is measured in Millimetre of mercury, millimetres of mercury (mmHg) above the surrounding atmospheric pressure, or in Pascal (unit), kilopascals (kPa). The difference between the systolic and diastolic pressures is known as pulse pressure, while the average pressure during a cardiac cycle is known as mean arterial pressure. Blood pressure is one of the vital signs—together with respiratory rate, heart rate, Oxygen saturation (me ...
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Right Gastric Vein
The right gastric vein (pyloric vein) drains blood from the lesser curvature of the stomach into the hepatic portal vein. It is part of the portal circulation. Structure The right gastric vein passes right along the lesser curvature of the stomach to the pylorus. Once there, it joins onto the portal vein before the duodenum. The prepyloric vein is the last connecting branch onto the right gastric vein, marking the end of the stomach, and draining the proximal part of the duodenum. Function The right gastric vein drains deoxygenated blood Blood is a body fluid in the circulatory system of humans and other vertebrates that delivers necessary substances such as nutrients and oxygen to the cells, and transports metabolic waste products away from those same cells. Blood is compo ... from the lesser curvature of the stomach. See also * Left gastric vein References External links * () {{Authority control Veins of the torso Stomach ...
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Left Gastric Vein
The left gastric vein (or coronary vein) is a vein that derives from tributaries draining the lesser curvature of the stomach. Structure The left gastric vein runs from right to left along the lesser curvature of the stomach. It passes to the esophageal opening of the stomach, where it receives some esophageal veins. It then turns backward and passes from left to right behind the omental bursa. It drains into the portal vein near the superior border of the pancreas. Function The left gastric vein drains deoxygenated blood from the lesser curvature of the stomach. It also acts as collaterals between the portal vein The portal vein or hepatic portal vein (HPV) is a blood vessel that carries blood from the gastrointestinal tract, gallbladder, pancreas and spleen to the liver. This blood contains nutrients and toxins extracted from digested contents. Approxima ... and the systemic venous system of the lower esophagus ( azygos vein). Clinical significance The esophageal ...
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Renal Portal System
A renal portal system is a portal venous system found in reptiles, and fish excluding hagfish and lampreys. It is not found in mammals. Its function is to supply blood to renal tubules when glomerular filtration is absent or downregulated. Description The main channel is the renal portal vein, developed from the posterior cardinal vein, which brings venous blood circulation from the tail and groin to the kidney, where it is shunted into a capillary network around the convoluted tubules. The blood then enters the renal vein, passing either through the subcardinal veins and into the posterior cardinal veins or through the posterior vena cava. There is no renal portal vein in mammals. Variations In lungfish and tetrapods, the renal portal vein is joined by a vein traveling upwards from the abdominal vein, which can bring venous blood from the hind limbs and ventral body wall into the renal portal system, or alternatively, enable blood from the tail and groin to pass into the hepa ...
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Hypophyseal Portal System
The hypophyseal portal system is a system of blood vessels in the microcirculation at the base of the brain, connecting the hypothalamus with the anterior pituitary. Its main function is to quickly transport and exchange hormones between the hypothalamus arcuate nucleus and anterior pituitary gland. The capillaries in the portal system are fenestrated (have many small channels with high vascular permeability) which allows a rapid exchange between the hypothalamus and the pituitary. The main hormones transported by the system include gonadotropin-releasing hormone, corticotropin-releasing hormone, growth hormone–releasing hormone, and thyrotropin-releasing hormone. Structure The blood supply and direction of flow in the hypophyseal portal system has been studied over many years on laboratory animals and human cadaver specimens with injection and vascular corrosion casting methods. Short portal vessels between the neural and anterior pituitary lobes provide an avenue for rap ...
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Portal Venous System
In the circulatory system of vertebrates, a portal venous system occurs when a capillary bed pools into another capillary bed through veins, without first going through the heart. Both capillary beds and the blood vessels that connect them are considered part of the portal venous system. Most capillary beds drain into venules and veins which then drain into the heart, not into another capillary bed. There are three portal systems, two venous: the hepatic portal system and the hypophyseal portal system; and one arterial (one capillary system between two arteries): the renal portal system. Unqualified, ''portal venous system'' usually refers to the hepatic portal system. For this reason, portal vein most commonly refers to the hepatic portal vein. The functional significance of such a system is that it transports products of one region directly to another region in relatively high concentrations. If the heart were involved in the blood circulation between those two regions, ...
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Hepatic Portal System
In human anatomy, the hepatic portal system or portal venous system is a system of veins comprising the portal vein and its tributaries. The other portal venous system in the body is the hypophyseal portal system. Structure Large veins that are considered part of the ''portal venous system'' are the: *Hepatic portal vein *Splenic vein *Superior mesenteric vein *Inferior mesenteric vein The superior mesenteric vein and the splenic vein come together to form the actual hepatic portal vein. The inferior mesenteric vein connects in the majority of people on the splenic vein, but in some people, it is known to connect on the portal vein or the superior mesenteric vein. Roughly, the portal venous system corresponds to areas supplied by the celiac trunk, the superior mesenteric artery, and the inferior mesenteric artery. Function The portal venous system is responsible for directing blood from parts of the gastrointestinal tract to the liver. Substances absorbed in the small int ...
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