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Myogenic Regulatory Factor
Myogenic regulatory factors (MRF) are basic helix-loop-helix (bHLH) transcription factors that regulate myogenesis: MyoD, Myf5, myogenin, and MRF4. These proteins contain a conserved basic DNA binding domain that binds the E box DNA motif. They dimerize with other HLH containing proteins through an HLH-HLH interaction. MRF Gene Family Evolution There are typically four vertebrate MRF paralogues which are homologous to typically a single MRF gene in non-vertebrates. These four genes are thought to have been duplicated in the two rounds of whole-genome duplication early in vertebrate evolution that played a role in the evolution of more complex vertebrate body plans. The four MRFs have four distinct expression profiles, though with some redundancy, as MyoD MyoD, also known as myoblast determination protein 1, is a protein in animals that plays a major role in regulating muscle differentiation. MyoD, which was discovered in the laboratory of Harold M. Weintraub, belo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Basic Helix-loop-helix
Basic or BASIC may refer to: Science and technology * BASIC, a computer programming language * Basic (chemistry), having the properties of a base * Basic access authentication, in HTTP Entertainment * ''Basic'' (film), a 2003 film * Basic, one of the languages in ''Star Wars'' Music * ''Basic'' (Glen Campbell album), 1978 * ''Basic'' (Robert Quine and Fred Maher album), 1984 * ''B.A.S.I.C.'' (Alpinestars album), 2000 * ''Basic'' (Brown Eyed Girls album), 2015 * ''B.A.S.I.C.'' (The Basics album), 2019 Places * Basic, Mississippi, a community in the US * BASIC countries, Brazil, South Africa, India and China in climate change negotiations Organizations * BASIC Bank Limited, government owned bank in Bangladesh * Basic Books, an American publisher Other uses * Basic (cigarette), a brand of cigarettes manufactured by the Altria Group (Philip Morris Company) * Basic (dance move), the dance move that defines the character of a particular dance * Basic (slang), a pejorative t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |