|
Cinchona
''Cinchona'' (pronounced or ) is a genus of flowering plants in the family Rubiaceae containing at least 23 species of trees and shrubs. All are native to the Tropical Andes, tropical Andean forests of western South America. A few species are reportedly naturalization (biology), naturalized in Central America, Jamaica, French Polynesia, Sulawesi, Saint Helena in the South Atlantic, and São Tomé and Príncipe off the coast of tropical Africa, and others have been cultivated in India and Java, where they have formed hybrids. ''Cinchona'' has been historically sought after for its medicinal value, as the bark of several species yields quinine and other alkaloids. These were the only effective treatments against malaria during the height of European colonialism, which made them of great economic and political importance. Trees in the genus are also known as fever trees because of their antimalarial properties. The artificial Quinine total synthesis, synthesis of quinine in 1944, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Quinine
Quinine is a medication used to treat malaria and babesiosis. This includes the treatment of malaria due to ''Plasmodium falciparum'' that is resistant to chloroquine when artesunate is not available. While sometimes used for nocturnal leg cramps, quinine is not recommended for this purpose due to the risk of serious side effects. It can be taken by mouth or intravenously. Malaria resistance to quinine occurs in certain areas of the world. Quinine is also used as an ingredient in tonic water and other beverages to impart a bitter taste. Common side effects include headache, tinnitus, ringing in the ears, vision issues, and sweating. More severe side effects include deafness, thrombocytopenia, low blood platelets, and an irregular heartbeat. Use can make one more prone to sunburn. While it is unclear if use during pregnancy carries potential for fetal harm, treating malaria during pregnancy with quinine when appropriate is still recommended. Quinine is an alkaloid, a natural ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clements Markham
Sir Clements Robert Markham (20 July 1830 – 30 January 1916) was an English geographer, explorer and writer. He was secretary of the Royal Geographical Society (RGS) between 1863 and 1888, and later served as the Society's president for a further 12 years. In the latter capacity he was mainly responsible for organising the British National Antarctic Expedition of 1901–1904, and for launching the polar career of Robert Falcon Scott. Markham began his career as a Royal Navy cadet and midshipman, during which time he went to the Arctic with in one of the many searches for Franklin's lost expedition. Later, Markham served as a geographer to the India Office, and was responsible for the collection of cinchona plants from their native Peruvian forests, and their transplantation in India. By this means, the Indian government acquired a home source from which quinine could be extracted. Markham also served as geographer to Sir Robert Napier, 1st Baron Napier of Magdala, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jesuit's Bark
Jesuit's bark, also known as cinchona bark, Peruvian bark or China bark, is a former remedy for malaria, as the bark contains quinine, used to treat the disease. The bark of several species of the genus ''Cinchona'', family Rubiaceae indigenous to the western Andes of South America, was introduced to Jesuit missionaries during the 17th century as a traditional treatment for malaria by indigenous people in Peru. History The postcolonial history of cinchona bark dates back more than 350 years. Circa 1650, the physician Sebastiano Bado declared that this bark had proved more precious to mankind than all the gold and silver that the Spaniards had obtained from South America. In the 18th century, the Italian professor of medicine Bernardino Ramazzini said that the introduction of Peruvian bark would be of the same importance to medicine that the discovery of gunpowder was to the art of war, an opinion endorsed by contemporary writers on the history of medicine. The value of Jesuit's ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cinchona Pubescens
''Cinchona pubescens'', also known as red cinchona and quina or kina (; ), is native to Central and South America. It is known as a medicinal plant for its bark's high quinine content- and has similar uses to '' C. officinalis'' in the production of quinine, most famously used for treatment of malaria. Description ''C. pubescens'' varies from small to large in size, growing to in height. When cut, the bark tends to turn red. Leaves are elliptical to oblate and thin. The leaves have pubescent teeth that turn red when they are older, hence its nickname the red quinine tree. Its flowers form in large panicles. They are pink and fragrant, while in the Galapagos they are light pink. Synonyms Taxonomic synonyms include: *''Cinchona caloptera'' Miq. *''Cinchona chomeliana'' Wedd. *''Cinchona coronulata'' Miq. *''Cinchona decurrentifolia'' Pav. *''Cinchona elliptica'' Wedd. *''Cinchona goudotiana'' Klotzsch ex Triana *''Cinchona govana'' Miq. *''Cinchona howardiana'' Kuntze *''Cinchona ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Malaria
Malaria is a Mosquito-borne disease, mosquito-borne infectious disease that affects vertebrates and ''Anopheles'' mosquitoes. Human malaria causes Signs and symptoms, symptoms that typically include fever, Fatigue (medical), fatigue, vomiting, and headaches. In severe cases, it can cause jaundice, Epileptic seizure, seizures, coma, or death. Symptoms usually begin 10 to 15 days after being bitten by an infected ''Anopheles'' mosquito. If not properly treated, people may have recurrences of the disease months later. In those who have recently survived an infection, reinfection usually causes milder symptoms. This partial Immunity (medical), resistance disappears over months to years if the person has no continuing exposure to malaria. The mosquitoes themselves are harmed by malaria, causing reduced lifespans in those infected by it. Malaria is caused by protozoa, single-celled microorganisms of the genus ''Plasmodium''. It is spread exclusively through bites of infected female ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tree
In botany, a tree is a perennial plant with an elongated stem, or trunk, usually supporting branches and leaves. In some usages, the definition of a tree may be narrower, e.g., including only woody plants with secondary growth, only plants that are usable as lumber, or only plants above a specified height. But wider definitions include taller palms, tree ferns, bananas, and bamboos. Trees are not a monophyletic taxonomic group but consist of a wide variety of plant species that have independently evolved a trunk and branches as a way to tower above other plants to compete for sunlight. The majority of tree species are angiosperms or hardwoods; of the rest, many are gymnosperms or softwoods. Trees tend to be long-lived, some trees reaching several thousand years old. Trees evolved around 400 million years ago, and it is estimated that there are around three trillion mature trees in the world currently. A tree typically has many secondary branches supported cle ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Luis Jerónimo De Cabrera, 4th Count Of Chinchón
Luis Jerónimo Fernández de Cabrera Bobadilla Cerda y Mendoza, 4th Count of Chinchón, also known as Luis Xerónimo Fernandes de Cabrera Bobadilla y Mendoza, (1589 in Madrid – October 28, 1647 in Madrid) was a Spanish nobleman, Comendador of Criptana, Alcaide of the Alcázar de Segovia, Treasurer of Aragón, and captain general and Viceroy of Peru, from January 14, 1629, to December 18, 1639. His wife, Ana de Osorio (1599–1625), is credited as being one of the first Europeans to be treated with quinine, and as the person who introduced that medicine into Europe. Birth Fernández de Cabrera Bobadilla was born in Madrid in 1589 (or perhaps 1590), into a family close to the Spanish throne. His parents were Diego Fernández de Cabrera, third Count of Chinchón and Inés Pacheco, the daughter of the marquis of Villena and 3rd Duke of Escalona, Diego López Pacheco, and Luisa Bernarda de Cabrera Bobadilla, third marquesa of Moya. Don Luis's parents were first cousins. He was ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of National Trees ...
This is a list of countries that have officially designated one or more trees as their national trees. Most species in the list are officially designated. Some species hold only an "unofficial" status. Additionally, the list includes trees that were once official but are no longer, as well as trees recognized as national symbols or for other symbolic roles. National trees See also * National emblem * Floral emblem * List of U.S. State and territory trees References {{DEFAULTSORT:List Of National Trees N Trees In botany, a tree is a perennial plant with an elongated stem, or trunk, usually supporting branches and leaves. In some usages, the definition of a tree may be narrower, e.g., including only woody plants with secondary growth, only p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Quinine Total Synthesis
The total synthesis of quinine, a naturally-occurring antimalarial drug, was developed over a 150-year period. The development of synthetic quinine is considered a milestone in organic chemistry although it has never been produced industrially as a substitute for natural occurring quinine. The subject has also been attended with some controversy: Gilbert Stork published the first stereoselective total synthesis of quinine in 2001, meanwhile shedding doubt on the earlier claim by Robert Burns Woodward and William Doering in 1944, claiming that the final steps required to convert their last synthetic intermediate, quinotoxine, into quinine would not have worked had Woodward and Doering attempted to perform the experiment. A 2001 editorial published in ''Chemical & Engineering News'' sided with Stork, but the controversy was eventually laid to rest once and for all when Robert Williams and coworkers successfully repeated Woodward's proposed conversion of quinotoxine to quinine in 20 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alkaloid
Alkaloids are a broad class of natural product, naturally occurring organic compounds that contain at least one nitrogen atom. Some synthetic compounds of similar structure may also be termed alkaloids. Alkaloids are produced by a large variety of organisms including bacteria, fungus, fungi, Medicinal plant, plants, and animals. They can be purified from crude extracts of these organisms by acid-base extraction, or solvent extractions followed by silica-gel column chromatography. Alkaloids have a wide range of pharmacology, pharmacological activities including antimalarial medication, antimalarial (e.g. quinine), asthma, antiasthma (e.g. ephedrine), chemotherapy, anticancer (e.g. omacetaxine mepesuccinate, homoharringtonine), cholinomimetic (e.g. galantamine), vasodilation, vasodilatory (e.g. vincamine), Antiarrhythmic agent, antiarrhythmic (e.g. quinidine), analgesic (e.g. morphine), antibacterial (e.g. chelerythrine), and anti-diabetic, antihyperglycemic activities (e.g. berb ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
European Colonialism
The phenomenon of colonization is one that stretches around the globe and across time. Ancient and medieval colonialism was practiced by various civilizations such as the Phoenicians, Babylonians, Persians, Greeks, Romans, Han Chinese, and Arabs. Colonialism in the modern sense began with the "Age of Discovery", led by the Portuguese, who became increasingly expansionist following the conquest of Ceuta in 1415, aiming to control navigation through the Strait of Gibraltar, spread Christianity, amass wealth and plunder, and suppress predation on Portuguese populations by Barbary pirates as part of a longstanding African slave trade – at that point a minor trade, one the Portuguese would soon reverse and surpass. Around 1450, based on North African fishing boats, a lighter ship was developed, the caravel, which could sail further and faster, was highly maneuverable, and could sail " into the wind". Enabled by new nautical technology, with the added incentive to find an alt ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Evergreen
In botany, an evergreen is a plant which has Leaf, foliage that remains green and functional throughout the year. This contrasts with deciduous plants, which lose their foliage completely during the winter or dry season. Consisting of many different species, the unique feature of evergreen plants lends itself to various environments and purposes. Evergreen species There are many different kinds of evergreen plants, including trees, shrubs, and vines. Evergreens include: * Most species of conifers (e.g., pine, Tsuga, hemlock, spruce, and fir), but not all (e.g., larch). * Live oak, holly, and "ancient" gymnosperms such as cycads * Many woody plants from frost-free climates * Rainforest trees * All eucalypts * Lycopodiopsida, Clubmosses and relatives * Most bamboos The Latin binomial term , meaning "always green", refers to the evergreen nature of the plant, for instance: :''Cupressus sempervirens'' (a cypress) :''Lonicera sempervirens'' (a honeysuckle) :''Sequoia sempervirens'' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
