William Murrell (physician)
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William Murrell (physician)
William Murrell (1853–1912) was an English physician, clinical pharmacologist, and toxicologist. Murrell is best known for being one of the first to recognize the clinical benefits of glyceryl trinitrate (also known as nitroglycerin) for the management of patients with angina pectoris. Early life And Education Murrell was born in London in 1853, the son of a lawyer. He was educated at Murray School in Wimbledon and University College in London. He trained at the University College and Brompton hospitals. At the University College hospital he taught physiology. He qualified for membership in the Royal College of Surgeons of England and Royal College of Physicians The Royal College of Physicians (RCP) is a British professional membership body dedicated to improving the practice of medicine, chiefly through the accreditation of physicians by examination. Founded by royal charter from King Henry VIII in 1 ... in 1877. The MD was granted by the University of Brussels in 1879 ...
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Nitroglycerin
Nitroglycerin (NG), (alternative spelling of nitroglycerine) also known as trinitroglycerin (TNG), nitro, glyceryl trinitrate (GTN), or 1,2,3-trinitroxypropane, is a dense, colorless, oily, explosive liquid most commonly produced by nitrating glycerol with white fuming nitric acid under conditions appropriate to the formation of the nitric acid ester. Chemically, the substance is an organic nitrate compound rather than a nitro compound, but the traditional name is retained. Invented in 1847 by Ascanio Sobrero, nitroglycerin has been used ever since as an active ingredient in the manufacture of explosives, namely dynamite, and as such it is employed in the construction, demolition, and mining industries. Since the 1880s, it has been used by militaries as an active ingredient and gelatinizer for nitrocellulose in some solid propellants such as cordite and ballistite. It is a major component in double-based smokeless propellants used by reloaders. Combined with nitrocellulose, hund ...
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Angina Pectoris
Angina, also known as angina pectoris, is chest pain or pressure, usually caused by insufficient blood flow to the heart muscle (myocardium). It is most commonly a symptom of coronary artery disease. Angina is typically the result of obstruction or spasm of the arteries that supply blood to the heart muscle. The main mechanism of coronary artery obstruction is atherosclerosis as part of coronary artery disease. Other causes of angina include abnormal heart rhythms, heart failure and, less commonly, anemia. The term derives from the Latin ''angere'' ("to strangle") and ''pectus'' ("chest"), and can therefore be translated as "a strangling feeling in the chest". There is a weak relationship between severity of angina and degree of oxygen deprivation in the heart muscle, however, the severity of angina does not always match the degree of oxygen deprivation to the heart or the risk of a myocardial infarction (heart attack). Some people may experience severe pain even though the ...
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Journal Of The American Medical Association
''The Journal of the American Medical Association'' (''JAMA'') is a peer-reviewed medical journal published 48 times a year by the American Medical Association. It publishes original research, reviews, and editorials covering all aspects of biomedicine. The journal was established in 1883 with Nathan Smith Davis as the founding editor. Kirsten Bibbins-Domingo of the University of California San Francisco became the journal editor-in-chief on July 1, 2022, succeeding Howard Bauchner of Boston University. History The journal was established in 1883 by the American Medical Association and superseded the ''Transactions of the American Medical Association''. ''Councilor's Bulletin'' was renamed the ''Bulletin of the American Medical Association'', which later was absorbed by the ''Journal of the American Medical Association''. In 1960, the journal obtained its current title, ''JAMA: The Journal of the American Medical Association''. The journal is commonly referred to as ''JAMA''. ...
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Royal College Of Surgeons Of England
The Royal College of Surgeons of England (RCS England) is an independent professional body and registered charity that promotes and advances standards of surgical care for patients, and regulates surgery and dentistry in England and Wales. The College is located at Lincoln's Inn Fields in London. It publishes multiple medical journals including the ''Annals of the Royal College of Surgeons of England'', the '' Faculty Dental Journal'', and the '' Bulletin of the Royal College of Surgeons of England''. History The origins of the college date to the fourteenth century with the foundation of the "Guild of Surgeons Within the City of London". Certain sources date this as occurring in 1368. There was ongoing dispute between the surgeons and barber surgeons until an agreement was signed between them in 1493, giving the fellowship of surgeons the power of incorporation. This union was formalised further in 1540 by Henry VIII between the Worshipful Company of Barbers (incorporated 14 ...
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Royal College Of Physicians
The Royal College of Physicians (RCP) is a British professional membership body dedicated to improving the practice of medicine, chiefly through the accreditation of physicians by examination. Founded by royal charter from King Henry VIII in 1518, the RCP is the oldest medical college in England. It set the first international standard in the classification of diseases, and its library contains medical texts of great historical interest. The college is sometimes referred to as the Royal College of Physicians of London to differentiate it from other similarly named bodies. The RCP drives improvements in health and healthcare through advocacy, education and research. Its 40,000 members work in hospitals and communities across over 30 medical specialties with around a fifth based in over 80 countries worldwide. The college hosts six training faculties: the Faculty of Forensic and Legal Medicine, the Faculty for Pharmaceutical Medicine, the Faculty of Occupational Medicine the Fac ...
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Free University Of Brussels (1834–1969)
The Free University of Brussels (french: Université libre de Bruxelles, or ULB; nl, Vrije Hogeschool te Brussel, later ''Vrije Universiteit Brussel'') was a university in Brussels, Belgium. Founded in 1834 on the principle of "free inquiry" (''libre examen''), its founders envisaged the institution as a free-thinker reaction to the traditional dominance of Catholicism in Belgian education. The institution was avowedly secular and particularly associated with Liberal political movements during the era of pillarisation. The Free University was one of Belgium's major universities, together with the Catholic University of Leuven and the state universities of Liège and Ghent. The "Linguistic Wars" affected the Free University, which split along language lines in 1969 in the aftermath of student unrest at Leuven the previous year. Today two institutions carry the "Free University of Brussels" name: the French-speaking Université libre de Bruxelles (ULB) and the Dutch-speaking Vr ...
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British Medical Journal
''The BMJ'' is a weekly peer-reviewed medical trade journal, published by the trade union the British Medical Association (BMA). ''The BMJ'' has editorial freedom from the BMA. It is one of the world's oldest general medical journals. Originally called the ''British Medical Journal'', the title was officially shortened to ''BMJ'' in 1988, and then changed to ''The BMJ'' in 2014. The journal is published by BMJ Publishing Group Ltd, a subsidiary of the British Medical Association (BMA). The editor-in-chief of ''The BMJ'' is Kamran Abbasi, who was appointed in January 2022. History The journal began publishing on 3 October 1840 as the ''Provincial Medical and Surgical Journal'' and quickly attracted the attention of physicians around the world through its publication of high-impact original research articles and unique case reports. The ''BMJ''s first editors were P. Hennis Green, lecturer on the diseases of children at the Hunterian School of Medicine, who also was its f ...
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The Lancet
''The Lancet'' is a weekly peer-reviewed general medical journal and one of the oldest of its kind. It is also the world's highest-impact academic journal. It was founded in England in 1823. The journal publishes original research articles, review articles ("seminars" and "reviews"), editorials, book reviews, correspondence, as well as news features and case reports. ''The Lancet'' has been owned by Elsevier since 1991, and its editor-in-chief since 1995 has been Richard Horton. The journal has editorial offices in London, New York City, and Beijing. History ''The Lancet'' was founded in 1823 by Thomas Wakley, an English surgeon who named it after the surgical instrument called a lancet (scalpel). Members of the Wakley family retained editorship of the journal until 1908. In 1921, ''The Lancet'' was acquired by Hodder & Stoughton. Elsevier acquired ''The Lancet'' from Hodder & Stoughton in 1991. Impact According to the ''Journal Citation Reports'', the journal has a 202 ...
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Alfred Nobel
Alfred Bernhard Nobel ( , ; 21 October 1833 – 10 December 1896) was a Swedes, Swedish chemist, engineer, inventor, businessman, and Philanthropy, philanthropist. He is best known for having bequeathed his fortune to establish the Nobel Prize, though he also made several important contributions to science, holding 355 patents in his lifetime. Nobel's most famous invention was dynamite, a safer and easier means of harnessing the explosive power of nitroglycerin; it was patented in 1867. Nobel displayed an early aptitude for science and learning, particularly in chemistry and languages; he became fluent in six languages and filed his first patent at age 24. He embarked on many business ventures Nobel family, with his family, most notably owning Bofors, an iron and steel producer that he developed into a major manufacturer of cannons and other armaments. Nobel was later inspired to donate his fortune to the Nobel Prize institution, which would annually recognize those who ...
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Karger
Karger Publishers (also: Karger Medical and Scientific Publishers, S. Karger AG) is an academic publisher of scientific and medical journals and books. The current CEO is Daniel Ebneter. History The company was founded in 1890 in Berlin by Samuel Karger, who remained at the helm of the company until his death in 1935. His son, Heinz Karger led the company until his death in 1959, and Heinz's son (and Samuel's grandson) Thomas Karger took over the leadership of the company; he was followed as the company leader by his eldest son, Steven Karger, and, most recently, by his youngest daughter, Gabriella Karger, who leads the publishing house now. Its first medical journal, '' Dermatologische Zeitschrift'' (later: ''Dermatologica'', now: ''Dermatology'') was established in 1893. The company published works from well-known scientists such as Sigmund Freud. Because of political pressure from the Nazi regime, the company was relocated to Basel, Switzerland, in 1937 and lost all German au ...
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1853 Births
Events January–March * January 6 – Florida Governor Thomas Brown signs legislation that provides public support for the new East Florida Seminary, leading to the establishment of the University of Florida. * January 8 – Taiping Rebellion: Zeng Guofan is ordered to assist the governor of Hunan in organising a militia force to search for local bandits. * January 12 – Taiping Rebellion: The Taiping army occupies Wuchang. * January 19 – Giuseppe Verdi's opera ''Il Trovatore'' premieres in performance at Teatro Apollo in Rome. * February 10 – Taiping Rebellion: Taiping forces assemble at Hanyang, Hankou, and Wuchang, for the march on Nanjing. * February 12 – The city of Puerto Montt is founded in the Reloncaví Sound, Chile. * February 22 – Washington University in St. Louis is founded as Eliot Seminary. * March – The clothing company Levi Strauss & Co. is founded in the United States. * March 4 – Inauguration of Franklin Pierce as 14th President of the ...
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1912 Deaths
Year 191 ( CXCI) was a common year starting on Friday (link will display the full calendar) of the Julian calendar. At the time, it was known as the Year of the Consulship of Apronianus and Bradua (or, less frequently, year 944 ''Ab urbe condita''). The denomination 191 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Parthia * King Vologases IV of Parthia dies after a 44-year reign, and is succeeded by his son Vologases V. China * A coalition of Chinese warlords from the east of Hangu Pass launches a punitive campaign against the warlord Dong Zhuo, who seized control of the central government in 189, and held the figurehead Emperor Xian hostage. After suffering some defeats against the coalition forces, Dong Zhuo forcefully relocates the imperial capital from Luoyang to Chang'an. Before leaving, Dong Zhuo orders his troops to loot the tombs of the H ...
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