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Vulvar Cancer
Vulvar cancer is a cancer of the vulva, the outer portion of the female genitals. It most commonly affects the labia majora. Less often, the labia minora, clitoris, or Bartholin's glands are affected. Symptoms include a lump, itchiness, changes in the skin, or bleeding from the vulva. Risk factors include vulvar intraepithelial neoplasia (VIN), HPV infection, genital warts, smoking, and many sexual partners. Most vulvar cancers are squamous cell cancers. Other types include adenocarcinoma, melanoma, sarcoma, and basal cell carcinoma. Diagnosis is suspected based on physical examination and confirmed by tissue biopsy. Routine screening is not recommended. Prevention may include HPV vaccination. Standard treatments may include surgery, radiation therapy, chemotherapy, and biologic therapy. Vulvar cancer newly affected about 44,200 people and resulted in 15,200 deaths globally in 2018. In the United States, it newly occurred in about 6,070 people with 1,280 deaths a year. Onset is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gynecologic Oncology
''Gynecologic Oncology'' is a Peer review, peer-reviewed medical journal covering all aspects of gynecologic oncology. The journal covers investigations relating to the etiology, diagnosis, and treatment of female cancers, as well as research from any of the disciplines related to this field of interest. It is published by Elsevier and is the official journal of the Society of Gynecologic Oncology. Abstracting and indexing The journal is abstracted and indexed in Current Contents/Clinical Medicine, Index Medicus, Science Citation Index, and Scopus. References External links * Elsevier academic journals Monthly journals Oncology journals Academic journals established in 1972 English-language journals Obstetrics and gynaecology journals {{oncology-journal-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Five-year Survival
The five-year survival rate is a type of survival rate for estimating the prognosis of a particular disease, normally calculated from the point of diagnosis. Lead time bias from earlier diagnosis can affect interpretation of the five-year survival rate. There are absolute and relative survival rates, but the latter are more useful and commonly used. __TOC__ Relative and absolute rates Five-year relative survival rates are more commonly cited in cancer statistics. Five-year absolute survival rates may sometimes also be cited. * Five-year ''absolute'' survival rates describe the percentage of patients alive five years after the disease is diagnosed. * Five-year ''relative'' survival rates describe the percentage of patients with a disease alive five years after the disease is diagnosed, divided by the percentage of the general population of corresponding sex and age alive after five years. Typically, cancer five-year relative survival rates are well below 100%, reflecting exces ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pruritis
An itch (also known as pruritus) is a sensation that causes a strong desire or reflex to scratch. Itches have resisted many attempts to be classified as any one type of sensory experience. Itches have many similarities to pain, and while both are unpleasant sensory experiences, their behavioral response patterns are different. Pain creates a withdrawal reflex, whereas itches leads to a scratch reflex. Unmyelinated nerve fibers for itches and pain both originate in the skin. Information for them is conveyed centrally in two distinct systems that both use the same nerve bundle and spinothalamic tract. Classification Most commonly, an itch is felt in one place. If it is felt all over the body, then it is called ''generalized itch'' or ''generalized pruritus''. Generalized itch is infrequently a symptom of a serious underlying condition, such as cholestatic liver disease. If the sensation of itching persists for six weeks or longer, then it is called ''chronic itch'' or ''chr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gynecology - (1918) (14750388526)
Gynaecology or gynecology (see American and British English spelling differences) is the area of medicine concerned with conditions affecting the female reproductive system. It is often paired with the field of obstetrics, which focuses on pregnancy and childbirth, thereby forming the combined area of obstetrics and gynaecology (OB-GYN). Gynaecology encompasses both primary and preventative care of issues related to female reproduction and sexual health, such as the uterus, vagina, fallopian tubes, ovaries, and breasts; subspecialties include family planning; minimally invasive surgery; pediatric and adolescent gynecology; and pelvic medicine and reconstructive surgery. While gynaecology has traditionally centered on cisgender women, it increasingly encompasses anyone with female organs, including transgender, intersex, and nonbinary individuals; however, many non-cis women face accessibility issues due to stigma, bias, and systemic exclusion in healthcare. Etymology The ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lymph Nodes
A lymph node, or lymph gland, is a kidney-shaped Organ (anatomy), organ of the lymphatic system and the adaptive immune system. A large number of lymph nodes are linked throughout the body by the lymphatic vessels. They are major sites of lymphocytes that include B cell, B and T cells. Lymph nodes are important for the proper functioning of the immune system, acting as filters for foreign particles including cancer cells, but have no detoxification function. In the lymphatic system, a lymph node is a Lymphatic system#Secondary lymphoid organs, secondary lymphoid organ. A lymph node is enclosed in a fibrous capsule and is made up of an outer cortex and an inner medulla. Lymph nodes become inflamed or enlarged in various diseases, which may range from trivial Pharyngitis, throat infections to life-threatening cancers. The condition of lymph nodes is very important in cancer staging, which decides the treatment to be used and determines the prognosis. Lymphadenopathy refers to gland ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Five-year Survival Rates
The five-year survival rate is a type of survival rate for estimating the prognosis of a particular disease, normally calculated from the point of diagnosis. Lead time bias from earlier diagnosis can affect interpretation of the five-year survival rate. There are absolute and relative survival rates, but the latter are more useful and commonly used. __TOC__ Relative and absolute rates Five-year relative survival rates are more commonly cited in cancer statistics. Five-year absolute survival rates may sometimes also be cited. * Five-year ''absolute'' survival rates describe the percentage of patients alive five years after the disease is diagnosed. * Five-year ''relative'' survival rates describe the percentage of patients with a disease alive five years after the disease is diagnosed, divided by the percentage of the general population of corresponding sex and age alive after five years. Typically, cancer five-year relative survival rates are well below 100%, reflecting excess m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Physical Examination
In a physical examination, medical examination, clinical examination, or medical checkup, a medical practitioner examines a patient for any possible medical signs or symptoms of a Disease, medical condition. It generally consists of a series of questions about the patient's medical history followed by an examination based on the reported symptoms. Together, the medical history and the physical examination help to determine a medical diagnosis, diagnosis and devise the treatment plan. These data then become part of the medical record. Types Routine The ''routine physical'', also known as ''general medical examination'', ''periodic health evaluation'', ''annual physical'', ''comprehensive medical exam'', ''general health check'', ''preventive health examination'', ''medical check-up'', or simply ''medical'', is a physical examination performed on an asymptomatic patient for medical screening purposes. These are normally performed by a pediatrician, family practice physician, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Squamous Cell Cancer
Squamous-cell carcinoma (SCC), also known as epidermoid carcinoma, comprises a number of different types of cancer that begin in squamous cells. These cells form on the surface of the skin, on the lining of hollow organs in the body, and on the lining of the respiratory and digestive tracts. The squamous-cell carcinomas of different body sites can show differences in their presented symptoms, natural history, prognosis, and response to treatment. By body location Human papillomavirus infection has been associated with SCCs of the oropharynx, lung, fingers, and anogenital region. Head and neck cancer About 90% of cases of head and neck cancer (cancer of the mouth, nasal cavity, nasopharynx, throat and associated structures) are due to SCC. Skin Cutaneous squamous-cell carcinoma is the second most common skin cancer, accounting for over 1 million cases in the United States each year. Thyroid Primary squamous-cell carcinoma of the thyroid shows an aggressive biological p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vulvar Intraepithelial Neoplasia
Vulvar intraepithelial neoplasia (VIN) refers to particular changes that can occur in the skin that covers the vulva. VIN is an intraepithelial neoplasia, and can disappear without treatment. VINs are benign but if the changes become more severe, there is a chance of cancer developing after many years, and so it is referred to as a precancerous condition. Classification Medically speaking, the term denotes a squamous intraepithelial lesion of the vulva that shows dysplasia with varying degrees of atypia. The epithelial basement membrane is intact and the lesion is thus not invasive but has invasive potential. The terminology of VIN evolved over several decades. In 1989 the Committee on Terminology, International Society for the Study of Vulvar Disease (ISSVD) replaced older terminology such as vulvar dystrophy, Bowen's disease, and Kraurosis vulvae by a new classification system for ''Epithelial Vulvar Disease'': * Nonneoplastic epithelial disorders of vulva and mucosa: ** Li ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bartholin's Gland
The Bartholin's glands (named after Caspar Bartholin the Younger; also called Bartholin glands or greater vestibular glands) are two pea-sized compound racemose glands, compound alveolar glandsManual of Obstetrics. (3rd ed.). Elsevier. pp. 1-16. . located slightly posterior and to the left and right of the Vagina#Vaginal opening and hymen, opening of the vagina. They secrete mucus to Vaginal lubrication, lubricate the vagina. They are homology (biology), homologous to bulbourethral glands in males. However, while Bartholin's glands are located in the superficial perineal pouch in females, bulbourethral glands are located in the deep perineal pouch in males. Their duct length is 1.5 to 2.0 cm and they open into fossa of vestibule of vagina, navicular fossa. The ducts are paired and they open on the surface of the vulva. Structure The embryological origin of the Bartholin's glands is derived from the urogenital sinus; therefore, the innervation and blood supply are via the pu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clitoris
In amniotes, the clitoris ( or ; : clitorises or clitorides) is a female sex organ. In humans, it is the vulva's most erogenous zone, erogenous area and generally the primary anatomical source of female Human sexuality, sexual pleasure. The clitoris is a complex structure, and its size and sensitivity can vary. The visible portion, the glans, of the clitoris is typically roughly the size and shape of a pea and is estimated to have at least 8,000 Nerve, nerve endings. * * Peters, B; Uloko, M; Isabey, PHow many Nerve Fibers Innervate the Human Clitoris? A Histomorphometric Evaluation of the Dorsal Nerve of the Clitoris 2 p.m. ET 27 October 2022, 23rd annual joint scientific meeting of Sexual Medicine Society of North America and International Society for Sexual Medicine Sexology, Sexological, medical, and psychological debate has focused on the clitoris, and it has been subject to social constructionist analyses and studies. Such discussions range from anatomical accuracy, g ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Labia Minora
The labia minora (Latin for 'smaller lips', : labium minus), also known as the inner labia, inner lips, or nymphae, are two flaps of skin that are part of the primate vulva, extending outwards from the inner Vagina#Vaginal opening and hymen, vaginal and Urethral meatus, urethral openings to encompass the Vulval vestibule, vestibule. At the glans clitoridis, each labium splits, above forming the clitoral hood, and below the frenulum of the clitoris. At the bottom, the labia meet at the ''labial commissure''. The labia minora vary widely in size, color and shape from individual to individual. The labia minora are situated between the labia majora and together form the labia. The labia minora are Homology (biology), homologous to the penile raphe and ventral penile skin in males. Structure and functioning The labia minora extend from the clitoris obliquely downward, laterally, and backward on either side of the vulval vestibule, ending between the bottom of the vulval vestibule and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
