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Victor Muñoz (biochemist)
Victor Muñoz is a biochemist whose focus has been on protein folding and design. He provided experimental evidence for a mechanism of protein folding called as " downhill folding". He has pioneered various computational and experimental techniques to study this mechanism as well as to gain insights into the general process of protein folding. Prof. Muñoz has used different standard biophysical techniques, such as Nuclear Magnetic Resonance (NMR), to unravel the downhill folding mechanism at an atom-by-atom level, using ultrafast laser temperature jump (T-jump) experiments for studying the kinetics of very fast folding proteins (microsecond timescales), driving Fluorescence Spectroscopy techniques (FRET) at single molecule level to study processes with fast dynamics as well as developing various computational models for quantitative analysis of a multitude of protein folding experimental data from various equilibrium and kinetics experiments. He has also been involved in design ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biochemist
Biochemists are scientists who are trained in biochemistry. They study chemical processes and chemical transformations in living organisms. Biochemists study DNA, proteins and Cell (biology), cell parts. The word "biochemist" is a portmanteau of "biological chemist." Biochemists also research how certain chemical reactions happen in cells and Tissue (biology), tissues and observe and record the effects of Product (chemistry), products in food additives and Medication, medicines. Biochemist researchers focus on playing and constructing research experiments, mainly for developing new products, updating existing products and analyzing said products. It is also the responsibility of a biochemist to present their research findings and create Grant writing, grant proposals to obtain Funding of science, funds for future research. Biochemists study aspects of the immune system, the expressions of genes, isolating, analyzing, and synthesizing different products, mutations that lead to ca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein Folding
Protein folding is the physical process by which a protein, after Protein biosynthesis, synthesis by a ribosome as a linear chain of Amino acid, amino acids, changes from an unstable random coil into a more ordered protein tertiary structure, three-dimensional structure. This structure permits the protein to become biologically functional or active. The folding of many proteins begins even during the translation of the polypeptide chain. The amino acids interact with each other to produce a well-defined three-dimensional structure, known as the protein's native state. This structure is determined by the amino-acid sequence or primary structure. The correct three-dimensional structure is essential to function, although some parts of functional proteins Intrinsically unstructured proteins, may remain unfolded, indicating that protein dynamics are important. Failure to fold into a native structure generally produces inactive proteins, but in some instances, misfolded proteins have ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
