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UCL Institute Of Neurology
The UCL Queen Square Institute of Neurology is an institute within the Faculty of Brain Sciences of University College London (UCL) and is located in London, United Kingdom. Together with the National Hospital for Neurology and Neurosurgery, an adjacent facility with which it cooperates closely, the institute forms a major centre for teaching, training and research in neurology and allied clinical and basic neurosciences. The institute has a staff of around 750 and 500 graduate students, an annual turnover of £102 million and occupies around 12,000 sq m of laboratory and office space. Four of the 12 most highly cited authors in neuroscience and behaviour in the world are currently based at the institute. The institute conducts research into a wide range of neurological diseases, including movement disorders, multiple sclerosis, epilepsy, brain cancer, stroke and brain injury, muscle and nerve disorders, cognitive dysfunction and dementia. It forms a key part of UCL Neuroscien ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
National Hospital For Neurology And Neurosurgery
The National Hospital for Neurology and Neurosurgery (informally the National Hospital or Queen Square) is a neurological hospital in Queen Square, London. It is part of the University College London Hospitals NHS Foundation Trust. It was the first hospital to be established in England dedicated exclusively to treating the diseases of the nervous system. It is closely associated with University College London (UCL) and in partnership with the UCL Institute of Neurology, which occupies the same site, is a major centre for neuroscience research. History The hospital was founded by Johanna Chandler as the National Hospital for the Paralysed and Epileptic at Queen Square in 1859. The hospital was completely rebuilt in the early 1880s: the East Wing was re-opened by Princess Helena in 1881 and the West Wing was re-opened by the Prince of Wales in 1885. In 1904, it adopted the name National Hospital for the Relief and Cure of the Paralysed and Epileptic. The hospital served as a s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Variant CJD
Variant may refer to: Arts and entertainment * ''Variant'' (magazine), a former British cultural magazine * Variant cover, an issue of comic books with varying cover art * ''Variant'' (novel), a novel by Robison Wells * "The Variant", 2021 episode of the TV series ''Loki'' **Sylvie (Marvel Cinematic Universe), a character who was originally referred to as the Variant **"Variant", a fictional term in the Marvel Cinematic Universe pertaining to the multiverse Gaming *Chess variant, a game derived from, related to or similar to chess in at least one respect *List of poker variants * List of ''Tetris'' variants Mathematics and computing *Loop variant, a decreasing value ensuring that a loop in a computer programme terminates *Variant (logic), a term or formula obtained from another one by consistently renaming all variables *Variant symlinks, a symbolic link to a file that has a variable name embedded in it *Variant type, in programming languages *Z-variant, unicode characters that ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Bovine Spongiform Encephalopathy
Bovine spongiform encephalopathy (BSE), commonly known as mad cow disease, is an incurable and always fatal neurodegenerative disease of cattle. Symptoms include abnormal behavior, trouble walking, and weight loss. Later in the course of the disease, the cow becomes unable to function normally. There is conflicting information about the time between infection and onset of symptoms. In 2002, the World Health Organization suggested it to be approximately four to five years. Time from onset of symptoms to death is generally weeks to months. Spread to humans is believed to result in variant Creutzfeldt–Jakob disease (vCJD). , a total of 233 cases of vCJD had been reported globally. BSE is thought to be due to an infection by a misfolded protein, known as a prion. Cattle are believed to have been infected by being fed meat-and-bone meal that contained either the remains of cattle who spontaneously developed the disease or scrapie-infected sheep products. The United Kingdo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Wellcome Centre For Human Neuroimaging
The Wellcome Centre for Human Neuroimaging, formerly the Wellcome Trust Centre for Neuroimaging at University College London (incorporating the Leopold Muller Functional Imaging Laboratory and the Wellcome Department of Imaging Neuroscience) is an interdisciplinary centre for neuroimaging research based in London, United Kingdom. Principal investigators working at the Centre include Professors Ray Dolan, Jon Driver, Richard Frackowiak, Chris Frith, Karl Friston, Eleanor Maguire, Cathy Price, and Geraint Rees. The Centre is located in Queen Square in the Bloomsbury area of Central London, adjacent to the National Hospital for Neurology and Neurosurgery. History 'The Functional Imaging Laboratory (FIL)', was founded in 1994 following a major grant award from the Wellcome Trust. This provided for a new building, capital equipment and core staff support. The award enabled a core group of scientists, based at the Medical Research Council Cyclotron Unit, at the Hammersmith Hospi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Neuroinflammation
Neuroinflammation is inflammation of the nervous tissue. It may be initiated in response to a variety of cues, including infection, traumatic brain injury,Ebert SE, Jensen P, Ozenne B, Armand S, Svarer C, Stenbaek DS ''et al.'' Molecular imaging of neuroinflammation in patients after mild traumatic brain injury: a longitudinal 123 I-CLINDE SPECT study. ''Eur J Neurol'' 2019. doi:10.1111/ene.13971. toxic metabolites, or autoimmunity. In the central nervous system (CNS), including the brain and spinal cord, microglia are the resident innate immune cells that are activated in response to these cues. The CNS is typically an immunologically privileged site because peripheral immune cells are generally blocked by the blood–brain barrier (BBB), a specialized structure composed of astrocytes and endothelial cells. However, circulating peripheral immune cells may surpass a compromised BBB and encounter neurons and glial cells expressing major histocompatibility complex molecules, perpetuati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Huntington's Disease
Huntington's disease (HD), also known as Huntington's chorea, is an incurable neurodegenerative disease that is mostly Genetic disorder#Autosomal dominant, inherited. It typically presents as a triad of progressive psychiatric, cognitive, and motor symptoms. The earliest symptoms are often subtle problems with mood or mental/psychiatric abilities, which precede the motor symptoms for many people. The definitive physical symptoms, including a general Ataxia, lack of coordination and an unsteady human gait, gait, eventually follow. Over time, the basal ganglia region of the brain gradually Basal ganglia disease#Huntington's disease, becomes damaged. The disease is primarily characterized by a distinctive hyperkinesia, hyperkinetic movement disorder known as ''chorea.'' Chorea classically presents as uncoordinated, involuntary, "dance-like" body movements that become more apparent as the disease advances. Physical abilities gradually worsen until Motor coordination, coordinated mo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Neurodegeneration
A neurodegenerative disease is caused by the progressive loss of neurons, in the process known as neurodegeneration. Neuronal damage may also ultimately result in their cell death, death. Neurodegenerative diseases include amyotrophic lateral sclerosis, multiple sclerosis, Parkinson's disease, Alzheimer's disease, Huntington's disease, multiple system atrophy, Tauopathy, tauopathies, and prion diseases. Neurodegeneration can be found in the brain at many different levels of neuronal circuitry, ranging from molecular to systemic. Because there is no known way to reverse the progressive degeneration of neurons, these diseases are considered to be incurable; however research has shown that the two major contributing factors to neurodegeneration are oxidative stress and inflammation. Biomedical research has revealed many similarities between these diseases at the subcellular level, including atypical protein assemblies (like proteinopathy) and induced cell death. These similarities su ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Research Assessment Exercise
The Research Assessment Exercise (RAE) was an exercise undertaken approximately every five years on behalf of the four UK higher education funding councils ( HEFCE, SHEFC, HEFCW, DELNI) to evaluate the quality of research undertaken by British higher education institutions. RAE submissions from each subject area (or ''unit of assessment'') are given a rank by a subject specialist peer review panel. The rankings are used to inform the allocation of quality weighted research funding (QR) each higher education institution receives from their national funding council. Previous RAEs took place in 1986, 1989, 1992, 1996 and 2001. The most recent results were published in December 2008. It was replaced by the Research Excellence Framework (REF) in 2014. Various media have produced league tables of institutions and disciplines based on the 2008 RAE results. Different methodologies lead to similar but non-identical rankings. History The first exercise of assessing of research in highe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Gray's Inn Road
Gray's Inn Road (or Grays Inn Road) is an important road in Central London, located in the London Borough of Camden. The road begins at its junction with Holborn at the City of London boundary, passes north through the Holborn and King's Cross districts and terminates at King's Cross railway station. It is designated as part of the A5200 road. As the home of the Honourable Society of Gray's Inn, one of England's four Inns of Court, Gray's Inn Road is known as a hub for law and legal professions in London. Gray's Inn Road is home to multiple scholarly institutes, including University College London's Eastman Dental Institute, a world-leading oral health institution, Westminster Kingsway College, and the City University of London's Inns of Court School of Law. Name The thoroughfare is first recorded as ''Purtepol Street'' in the 13th century, when the area formed part of Portpool Manor. After Reginald de Grey, 1st Baron Grey de Wilton purchased the area, his name soon ca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Eastman Dental Hospital
The Eastman Dental Hospital was based on Gray's Inn Road until it co-located with the University College London ear, nose, throat, balance and hearing services on Huntley Street, London, as the Royal National ENT and Eastman Dental Hospitals in October 2019. The hospital continues to provide specialist dental treatment as well as ear, nose, throat, hearing, speech and balance services and is part of the University College London Hospitals NHS Foundation Trust. The dental hospital is closely associated with University College London (UCL), and has a partnership with the UCL Eastman Dental Institute, which has stayed at the Gray's Inn Road site. It is a major centre for dental research and the largest provider of postgraduate teaching and training in dentistry in Europe. In 2009, there were more than 22,000 orthodontic appointments at the hospital, making its orthodontic department one of the largest in the UK. The hospital is part of both the UCLH/UCL Biomedical Research Cen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
