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Trabectome
The Trabectome is a surgical device that can be used for ab interno trabeculotomy, a minimally invasive glaucoma surgery for the surgical management of adult, juvenile, and infantile glaucoma. The trabecular meshwork is a major site of resistance to aqueous humor outflow. As angle surgeries such as Trabectome follow the physiologic outflow pathway, the risk of complications is significantly lower than filtering surgeries. Hypotony with damage to the macula (hypotony maculopathy), can occur with pressures below 5 mmHg, for instance, after traditional trabeculectomy, because of the episcleral venous pressure limit. The Trabectome handpiece is inserted into the anterior chamber, its tip positioned into Schlemm's canal, and advanced to the left and to the right. Different from cautery, the tip generates plasma to molecularize the trabecular meshwork and remove it drag-free and with minimal thermal effect. Active irrigation of the trabectome surgery system helps to keep the anterior c ...
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Infantile Glaucoma
Primary congenital glaucoma is a rare eye condition that is present at birth or develops early in childhood. It occurs due to improper drainage of the eye's fluids, which leads to increased pressure inside the eye, known as intraocular pressure. This elevated pressure can damage the optic nerve which will result in permanent vision loss. It is also known as pediatric glaucoma or childhood glaucoma, and was previously known as trabeculodysgenesis or goniodysgenesis. Types Primary congenital glaucoma is classified into three subtypes: * true congenital glaucoma, which causes signs of increased intraocular pressure within the first month of life, * infantile glaucoma, which presents between one month and three years, and * juvenile glaucoma, which becomes clinically apparent after three years of age and before age 40. Primary juvenile glaucoma Primary juvenile glaucoma becomes apparent between the ages of 3 and 40. It develops due to ocular hypertension and is diagnosed between t ...
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Hypotony Maculopathy
Hypotony maculopathy is maculopathy due to very low intraocular pressure known as ocular hypotony. Maculopathy occurs either due to increased outflow of aqueous humor through angle of anterior chamber or less commonly, due to decreased aqueous humor secretion by ciliary body. Description Hypotony maculopathy is maculopathy due to ocular hypotony. Fundus examination may reveal abnormalities like chorioretinal folds, optic nerve head swelling (papilledema) and tortuosity of blood vessels. Causes Maculopathy occurs either due to increased outflow of aqueous humor through angle of anterior chamber or less commonly, due to decreased aqueous humor secretion by ciliary body. Chronic inflammation within the eye including iridocyclitis, medications including anti glaucoma drugs, or proliferative vitreoretinopathy causes decreased production. Increased outflow or aqueous loss may occur following a glaucoma surgery, trauma, post-surgical wound leak from the eye, cyclodialysis cleft, ...
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Schlemm's Canal
Schlemm's canal, also known as the canal of Schlemm, and as the scleral venous sinus, is a circular Lymph, lymphatic-like vessel in the human eye, eye. It collects aqueous humor from the anterior chamber and delivers it into the episcleral blood vessels. Canaloplasty may be used to widen it. Structure Schlemm's canal is an endothelium-lined tube, resembling that of a lymphatic vessel. On the inside of the canal, nearest to the aqueous humor, it is covered and held open by the trabecular meshwork. This creates outflow resistance against the Aqueous humour, aqueous humor. Development While Schlemm's canal has generally been considered as a vein or a scleral venous sinus, the canal is similar to the lymphatic system, lymphatic vasculature. It is never filled with blood in physiological settings as it does not receive arterial blood circulation. Schlemm's canal displays several features of lymphatic endothelium, including the expression of PROX1, VEGFR3, CCL21, FOXC2, but lacked th ...
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Surgical Instruments
A surgical instrument is a medical device for performing specific actions or carrying out desired effects during a surgery or operation, such as modifying biological tissue, or to provide access for viewing it. Over time, many different kinds of surgical instruments and tools have been invented. Some surgical instruments are designed for general use in all sorts of surgeries, while others are designed for only certain specialties or specific procedures. Classification of surgical instruments helps surgeons to understand the functions and purposes of the instruments. With the goal of optimizing surgical results and performing more difficult operations, more instruments continue to be invented in the modern era. History Many different kinds of surgical instruments and tools have been invented and some have been repurposed as medical knowledge and surgical practices have developed. As surgery practice diversified, some tools are advanced for higher accuracy and stability while som ...
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