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Toenail
A nail is a claw-like plate found at the tip of the fingers and toes on most primates. Nails correspond to the claws found in other animals. Fingernails and toenails are made of a tough protective protein called alpha-keratin, which is a polymer. Alpha-keratin is found in the hooves, claws, and horns of vertebrates. Structure The nail consists of the nail plate, the nail matrix and the nail bed below it, and the grooves surrounding it. Parts of the nail The matrix, sometimes called the ''matrix unguis'', keratogenous membrane, nail matrix, or onychostroma, is the active tissue (or germinal matrix) that generates cells, which harden as they move outward from the nail root to the nail plate. It is the part of the nail bed that is beneath the nail and contains nerves, lymph and blood vessels. The matrix produces cells that become the nail plate. The width and thickness of the nail plate is determined by the size, length, and thickness of the matrix, while the shape of the fin ...
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Lunula (anatomy)
The lunula, or lunulae (pl.) (), is the crescent-shaped whitish area of the bed of a fingernail or toenail. In humans, it appears by week 14 of gestation, and has a primary structural role in defining the free edge of the distal nail plate (the part of the nail that grows outward). Appearance It is located at the end of the nail (that is closest to the skin of the finger), but it still lies under the nail. It is not actually white but only appears so when it is seen through the nail. Outlining the nail matrix, the lunula is a very delicate part of the nail structure. If one damages the lunula, the nail will be permanently deformed. Even when the totality of the nail is removed, the lunula remains in place and is similar in appearance to another smaller fingernail embedded in the nail bed. In most cases, it is half-moon-shaped and has unique histologic features. Examinations concluded that the lunula is an area of loose dermis with lesser developed collagen bundles. It appears ...
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Eponychium
In human anatomy, the eponychium is the thickened layer of skin at the base of the fingernails and toenails. It can also be called the medial or proximal nail fold. The eponychium differs from the cuticle; the eponychium comprises live skin cells whilst the cuticle is dead skin cells. Its function is to protect the area between the nail and epidermis from exposure to bacteria. The vascularization pattern is similar to that of perionychium. In hoofed animals, the eponychium is the deciduous hoof capsule in fetuses and newborn foals, and is a part of the permanent hoof in older animals. The word ''eponychium'' comes . See also * Hyponychium The hyponychium is the area of epithelium, particularly the thickened portion, underlying the free edge of the nail plate on the nail. Its proximal border is immediately distal to distal limit of nail bed—a.k.a. the onychodermal band (the lin ... * Lunula References Nail anatomy {{anatomy-stub ...
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Human Nail Anatomy
Humans (''Homo sapiens'') are the most abundant and widespread species of primate, characterized by bipedalism and exceptional cognitive skills due to a large and complex brain. This has enabled the development of advanced tools, culture, and language. Humans are highly social and tend to live in complex social structures composed of many cooperating and competing groups, from families and kinship networks to political states. Social interactions between humans have established a wide variety of values, social norms, and rituals, which bolster human society. Its intelligence and its desire to understand and influence the environment and to explain and manipulate phenomena have motivated humanity's development of science, philosophy, mythology, religion, and other fields of study. Although some scientists equate the term ''humans'' with all members of the genus ''Homo'', in common usage, it generally refers to ''Homo sapiens'', the only extant member. Anatomically modern hu ...
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Primate
Primates are a diverse order (biology), order of mammals. They are divided into the Strepsirrhini, strepsirrhines, which include the lemurs, galagos, and lorisids, and the Haplorhini, haplorhines, which include the Tarsiiformes, tarsiers and the Simiiformes, simians (monkeys and apes, the latter including humans). Primates arose 85–55 million years ago first from small Terrestrial animal, terrestrial mammals, which adapted to living in the trees of tropical forests: many primate characteristics represent adaptations to life in this challenging environment, including large brains, visual acuity, color vision, a shoulder girdle allowing a large degree of movement in the shoulder joint, and dextrous hands. Primates range in size from Madame Berthe's mouse lemur, which weighs , to the eastern gorilla, weighing over . There are 376–524 species of living primates, depending on which classification is used. New primate species continue to be discovered: over 25 species were d ...
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Cuticle
A cuticle (), or cuticula, is any of a variety of tough but flexible, non-mineral outer coverings of an organism, or parts of an organism, that provide protection. Various types of "cuticle" are non-homologous, differing in their origin, structure, function, and chemical composition. Human anatomy In human anatomy, "cuticle" can refer to several structures, but it is used in general parlance, and even by medical professionals, to refer to the thickened layer of skin surrounding fingernails and toenails (the eponychium), and to refer to the superficial layer of overlapping cells covering the hair shaft ( cuticula pili), consisting of dead cells, that locks the hair into its follicle. It can also be used as a synonym for the epidermis, the outer layer of skin. Cuticle of invertebrates In zoology, the invertebrate cuticle or cuticula is a multi-layered structure outside the epidermis of many invertebrates, notably roundworms and arthropods, in which it forms an exoskelet ...
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Matrix (biology)
In biology, matrix (plural: matrices) is the material (or tissue) in between a eukaryotic organism's cells. The structure of connective tissues is an extracellular matrix. Fingernails and toenails grow from matrices. It is found in various connective tissues. It is generally used as a jelly-like structure instead of cytoplasm in connective tissue. Tissue matrices Extracellular matrix (ECM) The main ingredients of the extracellular matrix are glycoproteins secreted by the cells. The most abundant glycoprotein in the ECM of most animal cells is collagen, which forms strong fibers outside the cells. In fact, collagen accounts for about 40% of the total protein in the human body. The collagen fibers are embedded in a network woven from proteoglycans. A proteoglycan molecule consists of a small core protein with many carbohydrate chains covalently attached, so that it may be up to 95% carbohydrate. Large proteoglycan complexes can form when hundreds of proteoglycans become nonc ...
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Paronychia
Paronychia is an inflammation of the skin around the nail, which can occur suddenly, when it is usually due to the bacterium ''Staphylococcus aureus'', or gradually when it is commonly caused by the fungus ''Candida albicans''. The term is from el, παρωνυχία from ''para'' 'around', ''onyx'' 'nail', and the abstract noun suffix '' -ia''. Risk factors include repeatedly washing hands and trauma to the cuticle such as may occur from repeated nail biting or hangnails. Treatment includes antibiotics and antifungals, and if pus is present, the consideration of incision and drainage. Paronychia is commonly misapplied as a synonym for herpetic whitlow or felon. Definition and etymology Paronychia is an inflammation of the skin around the nail, which can occur suddenly (acute), when it is usually due to the bacterium ''Staphylococcus aureus'', or gradually (chronic) when it is commonly caused by ''Candida albicans''. The term is from el, παρωνυχία from ''p ...
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Epithelium
Epithelium or epithelial tissue is one of the four basic types of animal tissue, along with connective tissue, muscle tissue and nervous tissue. It is a thin, continuous, protective layer of compactly packed cells with a little intercellular matrix. Epithelial tissues line the outer surfaces of organs and blood vessels throughout the body, as well as the inner surfaces of cavities in many internal organs. An example is the epidermis, the outermost layer of the skin. There are three principal shapes of epithelial cell: squamous (scaly), columnar, and cuboidal. These can be arranged in a singular layer of cells as simple epithelium, either squamous, columnar, or cuboidal, or in layers of two or more cells deep as stratified (layered), or ''compound'', either squamous, columnar or cuboidal. In some tissues, a layer of columnar cells may appear to be stratified due to the placement of the nuclei. This sort of tissue is called pseudostratified. All glands are made up of epi ...
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Synonym
A synonym is a word, morpheme, or phrase that means exactly or nearly the same as another word, morpheme, or phrase in a given language. For example, in the English language, the words ''begin'', ''start'', ''commence'', and ''initiate'' are all synonyms of one another: they are ''synonymous''. The standard test for synonymy is substitution: one form can be replaced by another in a sentence without changing its meaning. Words are considered synonymous in only one particular sense: for example, ''long'' and ''extended'' in the context ''long time'' or ''extended time'' are synonymous, but ''long'' cannot be used in the phrase ''extended family''. Synonyms with exactly the same meaning share a seme or denotational sememe, whereas those with inexactly similar meanings share a broader denotational or connotational sememe and thus overlap within a semantic field. The former are sometimes called cognitive synonyms and the latter, near-synonyms, plesionyms or poecilonyms. Lexicogr ...
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Hyponychium
The hyponychium is the area of epithelium, particularly the thickened portion, underlying the free edge of the nail plate on the nail. Its proximal border is immediately distal to distal limit of nail bed—a.k.a. the onychodermal band (the line Line most often refers to: * Line (geometry), object with zero thickness and curvature that stretches to infinity * Telephone line, a single-user circuit on a telephone communication system Line, lines, The Line, or LINE may also refer to: Art ... along the interface of the nail bed and the nail plate). Its distal border the free edge of the nail plate—or where that edge would project downwards onto the epidermis. It is sometimes called "the quick" (in its archaic meaning of "living"), as in the phrase cut to the quick. See also * Eponychium References Nail anatomy {{anatomy-stub ...
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Epidermis (skin)
The epidermis is the outermost of the three layers that comprise the skin, the inner layers being the dermis and hypodermis. The epidermis layer provides a barrier to infection from environmental pathogens and regulates the amount of water released from the body into the atmosphere through transepidermal water loss. The epidermis is composed of multiple layers of flattened cells that overlie a base layer ( stratum basale) composed of columnar cells arranged perpendicularly. The layers of cells develop from stem cells in the basal layer. The human epidermis is a familiar example of epithelium, particularly a stratified squamous epithelium. The word epidermis is derived through Latin , itself and . Something related to or part of the epidermis is termed epidermal. Structure Cellular components The epidermis primarily consists of keratinocytes ( proliferating basal and differentiated suprabasal), which comprise 90% of its cells, but also contains melanocytes, Lange ...
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Phalanx Bone
The phalanges (singular: ''phalanx'' ) are digital bones in the hands and feet of most vertebrates. In primates, the thumbs and big toes have two phalanges while the other digits have three phalanges. The phalanges are classed as long bones. Structure The phalanges are the bones that make up the fingers of the hand and the toes of the foot. There are 56 phalanges in the human body, with fourteen on each hand and foot. Three phalanges are present on each finger and toe, with the exception of the thumb and large toe, which possess only two. The middle and far phalanges of the fifth toes are often fused together (symphalangism). The phalanges of the hand are commonly known as the finger bones. The phalanges of the foot differ from the hand in that they are often shorter and more compressed, especially in the proximal phalanges, those closest to the torso. A phalanx is named according to whether it is proximal, middle, or distal and its associated finger or toe. The proxi ...
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