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Scandinavian Hunter-Gatherer
In archaeogenetics, the term Scandinavian Hunter-Gatherer (SHG) is the name given to a distinct ancestral component that represents descent from Mesolithic hunter-gatherers of Scandinavia. Genetic studies suggest that the SHGs were a mix of Western Hunter-Gatherers (WHGs) initially populating Scandinavia from the south during the Holocene, and Eastern Hunter-Gatherers (EHGs), who later entered Scandinavia from the north along the Norwegian coast. During the Neolithic, they admixed further with Early European Farmers (EEFs) and Western Steppe Herders (WSHs). Genetic continuity has been detected between the SHGs and members of the Pitted Ware culture (PWC), and to a certain degree, between SHGs and modern northern Europeans. The Sámi, on the other hand, have been found to be completely unrelated to PWC. Research Scandinavian Hunter-Gatherers (SHG) were identified as a distinct ancestral component in a study published in ''Nature'' in 2014. A number of remains examined at Motala, ...
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Archaeogenetics
Archaeogenetics is the study of ancient DNA using various molecular genetic methods and DNA resources. This form of genetic analysis can be applied to human, animal, and plant specimens. Ancient DNA can be extracted from various fossilized specimens including bones, eggshells, and artificially preserved tissues in human and animal specimens. In plants, Ancient DNA can be extracted from seeds and tissue. Archaeogenetics provides us with genetic evidence of ancient population group migrations, domestication events, and plant and animal evolution. The ancient DNA cross referenced with the DNA of relative modern genetic populations allows researchers to run comparison studies that provide a more complete analysis when ancient DNA is compromised. Archaeogenetics receives its name from the Greek word ''arkhaios'', meaning "ancient", and the term ''genetics'', meaning "the study of heredity". The term archaeogenetics was conceived by archaeologist Colin Renfrew. In February 2021, scientis ...
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Haplogroup I-M170
Haplogroup I (M170) is a Y-chromosome DNA haplogroup. It is a subgroup of haplogroup IJ, which itself is a derivative of the haplogroup IJK. Subclades I1 and I2 can be found in most present-day European populations, with peaks in some Northern European and Southeastern European countries. Haplogroup I appears to have arisen in Europe, so far being found in Palaeolithic sites throughout Europe (Fu 2016), but not outside it. It diverged from common ancestor IJ* about 43,000 years B.P. (Karafet 2008). Early evidence for haplogroup J has been found in the Caucasus and Iran (Jones 2015, Fu 2016). In addition, living examples of the precursor Haplogroup IJ* have been found only in Iran, among the Mazandarani and ethnic Persians from Fars. This may indicate that IJ originated in South West Asia. Haplogroup I has been found in multiple individuals belonging to the Gravettian culture. The Gravettians expanded westwards from the far corner of Eastern Europe, likely Russia, to Cent ...
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Sodium/potassium/calcium Exchanger 5
Sodium/potassium/calcium exchanger 5 (NCKX5), also known as solute carrier family 24 member 5 (SLC24A5), is a protein that in humans is encoded by the ''SLC24A5'' gene that has a major influence on natural skin colour variation. The NCKX5 protein is a member of the potassium-dependent sodium/calcium exchanger family. Sequence variation in the ''SLC24A5'' gene, particularly a non-synonymous SNP changing the amino acid at position 111 in NCKX5 from alanine to threonine, has been associated with differences in skin pigmentation. The SLC24A5 gene's derived threonine or ''Ala111Thr'' allele (rs1426654) has been shown to be a major factor in the light skin tone of Europeans compared to Sub-Saharan Africans, and is believed to represent as much as 25–40% of the average skin tone difference between Europeans and West Africans. * Possibly originating as long as 19,000 years ago, it has been the subject of selection in the ancestors of Europeans as recently as within the last 5,000 y ...
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Ahrensburg Culture
The Ahrensburg culture or Ahrensburgian (c. 12,900 to 11,700 BP) was a late Upper Paleolithic nomadic hunter culture (or technocomplex) in north-central Europe during the Younger Dryas, the last spell of cold at the end of the Weichsel glaciation resulting in deforestation and the formation of a tundra with bushy arctic white birch and rowan. The most important prey was the wild reindeer. The earliest definite finds of arrow and bow date to this culture, though these weapons might have been invented earlier. The Ahrensburgian was preceded by the Hamburg and Federmesser cultures and superseded by the Maglemosian and Swiderian cultures. Ahrensburgian finds were made in southern and western Scandinavia, the North German plain and western Poland. The Ahrensburgian area also included vast stretches of land now at the bottom of the North and Baltic Sea, since during the Younger Dryas the coastline took a much more northern course than today. The culture is named after a tunn ...
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Y-DNA
The Y chromosome is one of two sex chromosomes (allosomes) in therian mammals, including humans, and many other animals. The other is the X chromosome. Y is normally the sex-determining chromosome in many species, since it is the presence or absence of Y that determines the male or female sex of offspring produced in sexual reproduction. In mammals, the Y chromosome contains the gene SRY, which triggers male development. The DNA in the human Y chromosome is composed of about 59 million base pairs, making it similar in size to chromosome 19. The Y chromosome is passed only from father to son. With a 30% difference between humans and chimpanzees, the Y chromosome is one of the fastest-evolving parts of the human genome. The human Y chromosome carries an estimated 100–200 genes, with between 45 and 73 of these being protein-coding. All single-copy Y-linked genes are hemizygous (present on only one chromosome) except in cases of aneuploidy such as XYY syndrome or XXYY syndrome. ...
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PLOS Biology
''PLOS Biology'' is a monthly peer-reviewed scientific journal covering all aspects of biology. Publication began on October 13, 2003. It is the first journal published by the Public Library of Science. The editor-in-chief is Nonia Pariente. In addition to research articles, the journal publishes magazine content aimed to be accessible to a broad audience. Article types in this section are essays, "unsolved mysteries", editorials, and synopses. Abstracting and indexing The journal is abstracted and indexed in: *Biological Abstracts *BIOSIS Previews *''Current Contents''/Agriculture, Biology & Environmental Sciences *''Current Contents''/Life Sciences *Chemical Abstracts Service * Embase *''Index Medicus''/MEDLINE/PubMed *Science Citation Index *Scopus *''The Zoological Record'' According to ''Journal Citation Reports'', the journal had a 2019 impact factor of 7.076. The journal does not list this impact factor on its website. Instead, the journal promotes the use of article level ...
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Switzerland
). Swiss law does not designate a ''capital'' as such, but the federal parliament and government are installed in Bern, while other federal institutions, such as the federal courts, are in other cities (Bellinzona, Lausanne, Luzern, Neuchâtel, St. Gallen a.o.). , coordinates = , largest_city = Zürich , official_languages = , englishmotto = "One for all, all for one" , religion_year = 2020 , religion_ref = , religion = , demonym = , german: Schweizer/Schweizerin, french: Suisse/Suissesse, it, svizzero/svizzera or , rm, Svizzer/Svizra , government_type = Federal assembly-independent directorial republic with elements of a direct democracy , leader_title1 = Federal Council , leader_name1 = , leader_title2 = , leader_name2 = Walter Thurnherr , legislature = Federal Assembly , upper_house = Council of ...
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Grotte Du Bichon
Grotte du Bichon is a karstic cave in the Swiss Jura, overlooking the river Doubs at an altitude of 846 m, some 5 km north of La Chaux-de-Fonds. It is the site of the discovery of the skeleton a hunter-gatherer of the Azilian (late Upper Paleolithic to early Mesolithic), dubbed "Bichon man" (''homme de Bichon''), a young male about 20 to 23 years old, carbon dated to 13,770–13,560 years ago ( 95% CI). The skeleton was discovered in 1956, about 15 m from the cave entrance, intermingled with the bones of a female brown bear, nine flint arrowheads and traces of charcoal. In 1991, flint chips were found embedded in the bear's third vertebra, without indication of healing, suggesting the interpretation that the bear was wounded by arrows, retreated into the cave, and was pursued by the hunter, who made a fire to fumigate the bear from the cave, but was killed by the dying animal. A genetic analysis of the man showed membership in the "West European Hunter-Gathe ...
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Cro-Magnon
Early European modern humans (EEMH), or Cro-Magnons, were the first early modern humans (''Homo sapiens'') to settle in Europe, migrating from Western Asia, continuously occupying the continent possibly from as early as 56,800 years ago. They interacted and interbred with the indigenous Neanderthals (''H. neanderthalensis'') of Europe and Western Asia, who went extinct 40,000 to 35,000 years ago; and from 37,000 years ago onwards all EEMH descended from a single founder population which contributes ancestry to present-day Europeans. Early European modern humans (EEMH) produced Upper Palaeolithic cultures, the first major one being the Aurignacian, which was succeeded by the Gravettian by 30,000 years ago. The Gravettian split into the Epi-Gravettian in the east and Solutrean in the west, due to major climate degradation during the Last Glacial Maximum (LGM), peaking 21,000 years ago. As Europe warmed, the Solutrean evolved into the Magdalenian by 20,000 years ago, and these pe ...
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Upper Paleolithic
The Upper Paleolithic (or Upper Palaeolithic) is the third and last subdivision of the Paleolithic or Old Stone Age. Very broadly, it dates to between 50,000 and 12,000 years ago (the beginning of the Holocene), according to some theories coinciding with the appearance of behavioral modernity in early modern humans, until the advent of the Neolithic Revolution and agriculture. Anatomically modern humans (i.e. ''Homo sapiens'') are believed to have emerged in Africa around 300,000 years ago, it has been argued by some that their ways of life changed relatively little from that of archaic humans of the Middle Paleolithic, until about 50,000 years ago, when there was a marked increase in the diversity of artefacts found associated with modern human remains. This period coincides with the most common date assigned to expansion of modern humans from Africa throughout Asia and Eurasia, which contributed to the extinction of the Neanderthals. The Upper Paleolithic has the earli ...
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Membrane-associated Transporter Protein
Membrane-associated transporter protein (MATP), also known as solute carrier family 45 member 2 (SLC45A2) or melanoma antigen AIM1, is a protein that in humans is encoded by the ''SLC45A2'' gene. Function SLC45A2 is a transporter protein that mediates melanin synthesis. It may regulate the pH of the melanosome, affecting tyrosinase activity. SLC45A2 is also a melanocyte differentiation antigen that is expressed in a high percentage of melanoma cell lines. A similar sequence gene in medaka fish, 'B,' encodes a transporter that mediates melanin synthesis. Mutations in this gene are a cause of oculocutaneous albinism type 4. Alternative splicing results in multiple transcript variants encoding different isoforms. Protein expression is localized to the melanosome, and analysis of the by knockdown of RNA expression leads to altered melanosome pH potentially altering tyrosinase function by affecting copper binding. In melanocytic cell types, the SLC45A2 gene is regulated by mic ...
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East Asia
East Asia is the eastern region of Asia, which is defined in both Geography, geographical and culture, ethno-cultural terms. The modern State (polity), states of East Asia include China, Japan, Mongolia, North Korea, South Korea, and Taiwan. China, North Korea, South Korea and Taiwan are all unrecognised by at least one other East Asian state due to severe ongoing War, political tensions in the region, specifically the division of Korea and the political status of Taiwan. Hong Kong and Macau, two small coastal Dependent territory, quasi-dependent territories located in the south of China, are officially highly autonomous but are under Chinese sovereignty. Economy of Japan, Japan, Economy of Taiwan, Taiwan, Economy of South Korea, South Korea, Economy of China, Mainland China, Economy of Hong Kong, Hong Kong, and Economy of Macau, Macau are among the world's largest and most prosperous economies. East Asia borders Siberia and the Russian Far East to the north, Southeast Asia to ...
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