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Smoker’s Macrophages
Smoker's macrophages are alveolar macrophages whose characteristics, including appearance, cellularity, phenotypes, immune response, and other functions, have been affected upon the exposure to cigarettes. These altered immune cells are derived from several signaling pathways and are able to induce numerous respiratory diseases. They are involved in asthma, chronic obstructive pulmonary diseases (COPD), pulmonary fibrosis, and lung cancer. Smoker’s macrophages are observed in both firsthand and secondhand smokers, so anyone exposed to cigarette contents, or cigarette smoke extract (CSE), would be susceptible to these macrophages, thus in turns leading to future complications. Alveolar macrophages are crucial in processing inhaled substances including cigarette chemicals and Particulates, particulate matter. The chemicals in tobacco, such as nicotine, Tar (tobacco residue), tar, and carbon monoxide, stimulate several physiological pathways, which influence the recruitment and func ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Marlboro Cigarettes
Marlboro (, ) is an American brand of cigarettes owned and manufactured by Philip Morris USA (a branch of Altria) within the United States and by Philip Morris International (PMI, now separate from Altria) in most global territories outside the US. The brand was introduced in 1924, initially marketed towards women before it evolved towards men during the 1950s. Marlboro would eventually become one of the world's most valuable brands and best-selling products, and it was widely known for its advertizing featuring the Marlboro Man, a fictional cowboy. Today, Marlboro continues to be one of the largest brand products of cigarettes. Marlboro's largest cigarette manufacturing plant is located in Richmond, Virginia, Richmond, Virginia. In Canada, a separate product using the Marlboro brand is owned and manufactured by Imperial Tobacco Canada, while the international product is distributed in Canada by a unit of PMI under the name "Rooftop". Also in India, a separate Marlboro product is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
