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Sir William Bowman, 1st Baronet
Sir William Bowman, 1st Baronet (20 July 1816 – 29 March 1892) was an English surgeon, histologist and anatomist. He is best known for his research using microscopes to study various human organs, though during his lifetime he pursued a successful career as an ophthalmologist. Life Born in Nantwich, Cheshire, third son of a banker and amateur botanist/geologist, Bowman attended Hazelwood School near Birmingham from 1826.Hale-White, W. (1935) "Sir William Bowman", pp. 177–188; in ''Great Doctors of the Nineteenth Century'', Edward Arnold & Co A childhood accident involving gunpowder is supposed to have interested him in medicine, and he was apprenticed to surgeon Joseph Hodgson at Birmingham General Hospital in 1832. He left Birmingham in 1837 to further his training as a surgeon and attended King's College London, where he served as a prosector under Robert Bentley Todd, a Professor of physiology. His earliest notable work was on the structure of striated muscle, for ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nantwich
Nantwich ( ) is a market town and civil parish in the unitary authority of Cheshire East in Cheshire, England. It has among the highest concentrations of listed buildings in England, with notably good examples of Tudor and Georgian architecture. At the 2021 census, the parish had a population of 14,045 and the built up area had a population of 18,740. History The origins of the settlement date to Roman times, when salt from Nantwich was used by the Roman garrisons at Chester (Deva Victrix) and Stoke-on-Trent as a preservative and a condiment. Salt has been used in the production of Cheshire cheese and in the tanning industry, both products of the dairy industry based in the Cheshire Plain around the town. ''Nant'' comes from the Welsh for brook or stream. '' Wich'' and '' wych'' are names used to denote brine springs or wells. In 1194 there is a reference to the town as being called ''Nametwihc'', which would indicate it was once the site of a pre-Roman Celtic nemeton ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Birmingham General Hospital
Birmingham General Hospital was a teaching hospital in Birmingham, England, founded in 1779 and closed in the mid-1990s. History Summer Lane In 1765, a committee for a proposed hospital, formed by John Ash (physician), John Ash and supported by Holte baronets, Sir Lister Holte, 5th Baronet, the Orlando Bridgeman, 1st Earl of Bradford, Earl of Bradford, Samuel Garbett, Sir Henry Gough, 1st Baronet, Henry Gough, Charles Bowyer Adderley, 1st Baron Norton, Charles Adderley, Matthew Boulton, John Baskerville, Sampson Lloyd and others, purchased: from a Mrs Dolphin, for £120 per acre. (Walmore Lane is now Lancaster Street.) However, work to erect the new hospital on that land stopped through lack of funds in 1766. Eventually, much of its funds came from the Birmingham Triennial Music Festival, the first of which was held over three days in September 1768, and which continued to fund the hospital into the 20th century. The hospital finally opened on 20 September 1779, giving ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cornea
The cornea is the transparency (optics), transparent front part of the eyeball which covers the Iris (anatomy), iris, pupil, and Anterior chamber of eyeball, anterior chamber. Along with the anterior chamber and Lens (anatomy), lens, the cornea Refraction, refracts light, accounting for approximately two-thirds of the eye's total optical power. In humans, the refractive power of the cornea is approximately 43 dioptres. The cornea can be reshaped by surgical procedures such as LASIK. While the cornea contributes most of the eye's focusing power, its Focus (optics), focus is fixed. Accommodation (eye), Accommodation (the refocusing of light to better view near objects) is accomplished by changing the geometry of the lens. Medical terms related to the cornea often start with the prefix "''wikt:kerat-, kerat-''" from the Ancient Greek, Greek word κέρας, ''horn''. Structure The cornea has myelinated, unmyelinated nerve endings sensitive to touch, temperature and chemicals; a to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Olfactory Mucosa
The olfactory mucosa is the Neuroepithelial cell, neuroepithelial mucosa lining the roof and upper parts of the Nasal septum, septum and lateral wall of the nasal cavity which contains Bipolar neuron, bipolar neurons of the primary receptor neurons of the Olfactory pathways, olfactory pathway, as well as supporting cells. The neurons' Dendrite, dendrites project towards the nasal cavity while their axons ascend through the cribriform plate as the Olfactory nerve, olfactory nerves. The part of the nasal cavity that is lined with olfactory mucosa is known as the olfactory region (''pars olfactoria tunicae mucosae nasi''), while the rest of the nasal cavity that is lined by ordinary respiratory mucosa is known as the respiratory region. Structure Olfactory mucosa lines about 5cm2 of the posterosuperior parts of the lateral nasal wall. Parts of the nasal cavity lined by olfactory mucosa include: parts of the roof of the nasal cavity, the superior nasal concha and some upper parts ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Histology
Histology, also known as microscopic anatomy or microanatomy, is the branch of biology that studies the microscopic anatomy of biological tissue (biology), tissues. Histology is the microscopic counterpart to gross anatomy, which looks at larger structures visible without a microscope. Although one may divide microscopic anatomy into ''organology'', the study of organs, ''histology'', the study of tissues, and ''cytology'', the study of cell (biology), cells, modern usage places all of these topics under the field of histology. In medicine, histopathology is the branch of histology that includes the microscopic identification and study of diseased tissue. In the field of paleontology, the term paleohistology refers to the histology of fossil organisms. Biological tissues Animal tissue classification There are four basic types of animal tissues: muscle tissue, nervous tissue, connective tissue, and epithelial tissue. All animal tissues are considered to be subtypes of these ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kidney
In humans, the kidneys are two reddish-brown bean-shaped blood-filtering organ (anatomy), organs that are a multilobar, multipapillary form of mammalian kidneys, usually without signs of external lobulation. They are located on the left and right in the retroperitoneal space, and in adult humans are about in length. They receive blood from the paired renal artery, renal arteries; blood exits into the paired renal veins. Each kidney is attached to a ureter, a tube that carries excreted urine to the urinary bladder, bladder. The kidney participates in the control of the volume of various body fluids, fluid osmolality, Acid-base homeostasis, acid-base balance, various electrolyte concentrations, and removal of toxins. Filtration occurs in the glomerulus (kidney), glomerulus: one-fifth of the blood volume that enters the kidneys is filtered. Examples of substances reabsorbed are solute-free water, sodium, bicarbonate, glucose, and amino acids. Examples of substances secreted are hy ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Renal Corpuscle
A renal corpuscle (or Malpighian body) is the blood-filtering component of the nephron of the kidney. It consists of a glomerulus - a tuft of capillaries composed of endothelial cells - and a glomerular capsule known as Bowman's capsule. Structure The renal corpuscle is composed of two structures, the glomerulus and the Bowman's capsule. The glomerulus is a small tuft of capillaries containing two cell types. Endothelial cells, which have large fenestrae, are not covered by diaphragms. Mesangial cells are modified smooth muscle cells that lie between the capillaries. They regulate blood flow by their contractile activity and secrete extracellular matrix, prostaglandins, and cytokines. Mesangial cells also have phagocytic activity, removing proteins and other molecules trapped in the glomerular basement membrane or filtration barrier. The Bowman's capsule has an outer parietal layer composed of simple squamous epithelium. The visceral layer, composed of modified sim ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nephron
The nephron is the minute or microscopic structural and functional unit of the kidney. It is composed of a renal corpuscle and a renal tubule. The renal corpuscle consists of a tuft of capillaries called a glomerulus and a cup-shaped structure called Bowman's capsule. The renal tubule extends from the capsule. The capsule and tubule are connected and are composed of epithelial cells with a lumen. A healthy adult has 1 to 1.5 million nephrons in each kidney. Blood is filtered as it passes through three layers: the endothelial cells of the capillary wall, its basement membrane, and between the podocyte foot processes of the lining of the capsule. The tubule has adjacent peritubular capillaries that run between the descending and ascending portions of the tubule. As the fluid from the capsule flows down into the tubule, it is processed by the epithelial cells lining the tubule: water is reabsorbed and substances are exchanged (some are added, others are removed); first wit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bowman's Capsule
Bowman's capsule (or the Bowman capsule, capsula glomeruli, or glomerular capsule) is a cup-like sac at the beginning of the Renal tubule, tubular component of a nephron in the mammalian kidney that performs the first step in the filtration of blood to form urine. A glomerulus (kidney), glomerulus is enclosed in the sac. Fluids from blood in the glomerulus are collected in the Bowman's capsule. Structure Outside the capsule, there are two poles: * The vascular pole is the side with the afferent arteriole and efferent arteriole. * The tubular pole, is the side with the proximal convoluted tubule. Inside the capsule, the layers are as follows, from outside to inside: *''Parietal layer''—A single layer of simple squamous epithelium. Does not function in filtration. *''Bowman's space (or "urinary space", or "capsular space")''—Between the visceral and parietal layers, into which the filtrate enters after passing through the filtration slits. *''Visceral layer''—Lies just above ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Royal Society
The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, recognising excellence in science, supporting outstanding science, providing scientific advice for policy, education and public engagement and fostering international and global co-operation. Founded on 28 November 1660, it was granted a royal charter by Charles II of England, King Charles II and is the oldest continuously existing scientific academy in the world. The society is governed by its Council, which is chaired by the society's president, according to a set of statutes and standing orders. The members of Council and the president are elected from and by its Fellows, the basic members of the society, who are themselves elected by existing Fellows. , there are about 1,700 fellows, allowed to use the postnominal title FRS (Fellow ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Muscle
Muscle is a soft tissue, one of the four basic types of animal tissue. There are three types of muscle tissue in vertebrates: skeletal muscle, cardiac muscle, and smooth muscle. Muscle tissue gives skeletal muscles the ability to muscle contraction, contract. Muscle tissue contains special Muscle contraction, contractile proteins called actin and myosin which interact to cause movement. Among many other muscle proteins, present are two regulatory proteins, troponin and tropomyosin. Muscle is formed during embryonic development, in a process known as myogenesis. Skeletal muscle tissue is striated consisting of elongated, multinucleate muscle cells called muscle fibers, and is responsible for movements of the body. Other tissues in skeletal muscle include tendons and perimysium. Smooth and cardiac muscle contract involuntarily, without conscious intervention. These muscle types may be activated both through the interaction of the central nervous system as well as by innervation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Physiology
Physiology (; ) is the science, scientific study of function (biology), functions and mechanism (biology), mechanisms in a life, living system. As a branches of science, subdiscipline of biology, physiology focuses on how organisms, organ systems, individual organ (biology), organs, cell (biology), cells, and biomolecules carry out chemistry, chemical and physics, physical functions in a living system. According to the classes of organisms, the field can be divided into clinical physiology, medical physiology, Zoology#Physiology, animal physiology, plant physiology, cell physiology, and comparative physiology. Central to physiological functioning are biophysics, biophysical and biochemical processes, homeostasis, homeostatic control mechanisms, and cell signaling, communication between cells. ''Physiological state'' is the condition of normal function. In contrast, ''pathology, pathological state'' refers to abnormality (behavior), abnormal conditions, including human diseases. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
