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Silvana Konermann
Silvana Konermann (born May 18, 1988) is a Swiss-American bioengineer and neuroscientist whose research focuses on CRISPR, genome engineering, Transcription (biology), transcription and epigenetics, and Alzheimer's disease. She is an assistant professor of biochemistry at Stanford University and co-founder and executive director of Arc Institute. Konermann's research laboratory aims to understand the molecular pathways that drive the development of Alzheimer’s disease using next-generation functional genomics, with the long-term goal of developing rationally targeted therapeutics for Neurodegenerative disease, neurodegenerative disorders. Biography Konermann attended Sächsisches Landesgymnasium Sankt Afra zu Meißen in Saxony, Germany. The minor planet 21546 Konermann was named in honor of her 2006 second-place finish at the International Science and Engineering Fair, Intel International Science and Engineering Fair. She received her Bachelor's degree in neurobiology from ET ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Baden, Switzerland
Baden (German language, German for "Thermal bath, baths"), sometimes unofficially, to distinguish it from Baden (other), other Badens, called Baden bei Zürich ("Baden near Zürich") or Baden im Aargau ("Baden in the Aargau"), is a town and a Municipalities of Switzerland, municipality in Switzerland. It is the main town or seat of the Baden (district, Aargau), district of Baden in the Cantons of Switzerland, canton of Aargau. Located northwest of Zürich in the Limmat Valley () mainly on the western side of the river Limmat, its mineral hot springs have been famed since at least the Switzerland in the Roman era, Roman era. Its official language is (the Swiss variety of Standard) Swiss Standard German, German, but the main spoken language is the local Alemannic German, Alemannic Swiss German (linguistics), Swiss-German dialect. the town had a population of over 19,000. Geography Downtown Baden is located on the left bank of the river Limmat in Limmat Valley, its eponym ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Alzheimer's Disease
Alzheimer's disease (AD) is a neurodegenerative disease and the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in remembering recent events. As the disease advances, symptoms can include problems with language, disorientation (including easily getting lost), mood swings, loss of motivation, self-neglect, and behavioral issues. As a person's condition declines, they often withdraw from family and society. Gradually, bodily functions are lost, ultimately leading to death. Although the speed of progression can vary, the average life expectancy following diagnosis is three to twelve years. The causes of Alzheimer's disease remain poorly understood. There are many environmental and genetic risk factors associated with its development. The strongest genetic risk factor is from an allele of apolipoprotein E. Other risk factors include a history of head injury, clinical depression, and high blood pressure. The progression of the di ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Salk Institute
The Salk Institute for Biological Studies is a scientific research institute in the La Jolla community of San Diego, California. The independent, non-profit institute was founded in 1960 by Jonas Salk, the developer of the polio vaccine; among the founding consultants were Jacob Bronowski and Francis Crick. Construction of the research facilities began in spring of 1962. The Salk Institute consistently ranks among the top institutions in the US in terms of research output and quality in the life sciences. As of October 2020, the Salk Institute employs 850 researchers in 60 research groups and focuses its research in three areas: molecular biology and genetics; neurosciences; and plant biology. Research topics include aging, cancer, diabetes, birth defects, Alzheimer's disease, Parkinson's disease, AIDS, and the neurobiology of American Sign Language. March of Dimes provided the initial funding and continues to support the institute. Research is funded by a variety of public sour ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Harold M
Harold may refer to: People * Harold (given name), including a list of persons and fictional characters with the name * Harold (surname), surname in the English language * András Arató, known in meme culture as "Hide the Pain Harold" Arts and entertainment * ''Harold'' (film), a 2008 comedy film * ''Harold'', an 1876 poem by Alfred, Lord Tennyson * ''Harold, the Last of the Saxons'', an 1848 book by Edward Bulwer-Lytton, 1st Baron Lytton * '' Harold or the Norman Conquest'', an opera by Frederic Cowen * ''Harold'', an 1885 opera by Eduard Nápravník * Harold, a character from the cartoon ''The Grim Adventures of Billy & Mandy'' * Harold & Kumar, a US movie; Harold/Harry is the main actor in the show. Places ;In the United States * Alpine, Los Angeles County, California, an erstwhile settlement that was also known as Harold * Harold, Florida, an unincorporated community * Harold, Kentucky, an unincorporated community * Harold, Missouri, an unincorporated commun ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
McGovern Institute For Brain Research
The McGovern Institute for Brain Research is a research institute within MIT. Its mission is to understand how the brain works and to discover new ways to prevent or treat brain disorders. The institute was founded in 2000 by Patrick McGovern and Lore Harp McGovern with a gift to MIT that is expected to total $350M over 20 years. Role The McGovern Institute conducts research into all aspects of brain function, including perception, cognition and action. It also conducts clinical and translational research on a wide range of brain disorders. The institute's core facilities include the Martinos Imaging Center, which provides neuroimaging technologies for human and animal research, including MRI, EEG and MEG. The McGovern Institute occupies approximately 85,000 sq ft (net) within the MIT Brain and Cognitive Sciences Complex. This building, which was completed in 2005, also houses the Picower Institute for Learning and Memory and the Department of Brain and Cognitive Science ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Broad Institute
The Eli and Edythe L. Broad Institute of MIT and Harvard (IPA: , pronunciation respelling: ), often referred to as the Broad Institute, is a biomedical and genomic research center located in Cambridge, Massachusetts, United States. The institute is independently governed and supported as a 501(c)(3) nonprofit research organization under the name Broad Institute Inc., and it partners with the Massachusetts Institute of Technology, Harvard University, and the five Harvard teaching hospitals. History The Broad Institute evolved from a decade of research collaborations among MIT and Harvard scientists. One cornerstone was the Center for Genome Research of Whitehead Institute at MIT. Founded in 1982, the Whitehead became a major center for genomics and the Human Genome Project. As early as 1995, scientists at the Whitehead started pilot projects in genomic medicine, forming an unofficial collaborative network among young scientists interested in genomic approaches to cancer and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
International Science And Engineering Fair
The Regeneron International Science and Engineering Fair (ISEF) is an annual science fair in the United States. It is owned and administered by the Society for Science, a 501(c)(3) non-profit organization based in Washington, D.C. Each May, more than 1800 students from roughly 75 countries and territories compete in the fair for scholarships, tuition grants, internships, scientific field trips and the grand prizes, including one $75,000 and two $50,000 college scholarships. All prizes together amount to over $8,000,000. Two major awards ceremonies are the Special Awards Organization Presentation (which now includes the Government Awards Presentations) and the Grand Awards Ceremony. History The International Science and Engineering Fair was founded in 1950 by Science Service (now the Society for Science) and was sponsored by Intel from 1997 to 2019. Regeneron Pharmaceuticals became the title sponsor for ISEF in 2020, but the event was cancelled that year and replaced with an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
21546 Konermann
Year 1546 ( MDXLVI) was a common year starting on Friday of the Julian calendar. Events January–March * January 11 – (''Tenbun 15, 20th day of the 12th month''): Ashikaga YoshifushiTitsingh p. 381 n.b., Ashikaga Yoshifushi changed his name to Yoshiteru in 1554 (''Tenbun 23, 2nd month'').] becomes 13th Shōgun of the '' Ashikaga shogunate''. * January 13 – Jeremias I of Constantinople, Patriarch of the Eastern Orthodox Church dies * January 18 – Blasco Núñez Vela first Spanish Viceroy of Peru fights with Gonzalo Pizarro at the Battle of Iñaquito and is killed. * February 12 – The Roman Catholic Archdiocese of Mexico, one of the largest in the world, with over four million Catholics, is created"Archdiocese of México" '' |
Minor Planet
According to the International Astronomical Union (IAU), a minor planet is an astronomical object in direct orbit around the Sun that is exclusively classified as neither a planet nor a comet. Before 2006, the IAU officially used the term ''minor planet'', but that year's meeting IAU definition of planet, reclassified minor planets and comets into dwarf planets and Small Solar System body, small Solar System bodies (SSSBs).Press release, IAU 2006 General Assembly: Result of the IAU Resolution votes International Astronomical Union, August 24, 2006. Accessed May 5, 2008. In contrast to the eight official planets of the Solar System, all minor planets fail to clearing the neighborhood, clear their orbital neighborhood. Minor planets include asteroids (near- ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Saxony
Saxony, officially the Free State of Saxony, is a landlocked state of Germany, bordering the states of Brandenburg, Saxony-Anhalt, Thuringia, and Bavaria, as well as the countries of Poland and the Czech Republic. Its capital is Dresden, and its largest city is Leipzig. Saxony is the List of German states by area, tenth largest of Germany's sixteen states, with an area of , and the List of German states by population, sixth most populous, with more than 4 million inhabitants. The term Saxony (other), Saxony has been in use for more than a millennium. It was used for the medieval Duchy of Saxony, the Electorate of Saxony of the Holy Roman Empire, the Kingdom of Saxony, and twice for a republic. The first Free State of Saxony was established in 1918 as a constituent state of the Weimar Republic. After World War II, it was under Soviet occupation before it became part of communist East Germany and was abolished by the government in 1952. Following German reunificat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Sächsisches Landesgymnasium Sankt Afra Zu Meißen
Sächsisches Landesgymnasium Sankt Afra zu Meißen is a boarding school for highly gifted students in the German city of Meissen, Saxony. Founded in 1543 as ''Fürstliche Landesschule'' and re-established in 2001, the stated aim of the school is to promote the intellectual and social development of highly gifted students. The costs for attending the school comply with the maxim of social balance; the boarding and schooling fees are considerably low in contrast to similar institutions. It is the first publicly funded school for highly gifted students in Germany and is a role model for similar schools. The school has no official English name. Its German name translates to "Saxon State Gymnasium Saint Afra in Meissen", and is derived from the former Augustinian monastery of the Canons Regular that had been built around the local Saint Afra church. Notable students and professors Students * Petrus Albinus * Karl Salomo Zachariae von Lingenthal * Christian Fürchtegott Gellert ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Neurodegenerative Disease
A neurodegenerative disease is caused by the progressive loss of neurons, in the process known as neurodegeneration. Neuronal damage may also ultimately result in their death. Neurodegenerative diseases include amyotrophic lateral sclerosis, multiple sclerosis, Parkinson's disease, Alzheimer's disease, Huntington's disease, multiple system atrophy, tauopathies, and prion diseases. Neurodegeneration can be found in the brain at many different levels of neuronal circuitry, ranging from molecular to systemic. Because there is no known way to reverse the progressive degeneration of neurons, these diseases are considered to be incurable; however research has shown that the two major contributing factors to neurodegeneration are oxidative stress and inflammation. Biomedical research has revealed many similarities between these diseases at the subcellular level, including atypical protein assemblies (like proteinopathy) and induced cell death. These similarities suggest that therap ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
