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Shionogi
is a Japanese pharmaceutical company best known for developing Crestor. Medical supply and brand name also uses katakana (シオノギ). Shionogi has business roots that date back to 1878, and was incorporated in 1919. Among the medicines produced are for hyperlipidaemia, antibiotics, and cancer medicines. In Japan it is particularly known as a producer of antimicrobial and antibiotics. Because of antibiotic resistance and slow growth of the antibiotic market, it has teamed up with US based Schering-Ploughmerged in 2009with Merck & Co) to become a sole marketing agent for its products in Japan. Shionogi had supported the initial formation of Ranbaxy Pharmaceuticals, a generic manufacturer based in India. In 2012 the company became a partial owner of ViiV Healthcare, a pharmaceutical company specialising in the development of therapies for HIV. The company is listed on the Tokyo Stock Exchange and Osaka Securities Exchange and is constituent of the Nikkei 225 stock index. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
ViiV Healthcare
ViiV Healthcare ( ) is a British multinational pharmaceutical company specializing in the research and development of medicines to treat and prevent HIV/AIDS. Its global headquarters is located in London. The company was created as a joint venture by GSK and Pfizer in November 2009, with both companies transferring their HIV assets to the new company.Jacks, Andre"GSK and Pfizer to Merge HIV PortfoliosFinancial Times. 16 April 2010 In 2012, Shionogi joined the company. As of December 2023, 76.5% of the company is owned by GSK, 13.5% by Pfizer and 10% by Shionogi. According to The Financial Times, the company's co-ownership structure may change depending on the achievement of certain milestones. ViiV Healthcare's products have a market share of approximately 32% of the global HIV therapy market, making it the second-largest healthcare company in the sector, after Gilead Sciences. ViiV Healthcare's global headquarters are in London in the United Kingdom, and the company h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chūō-ku, Osaka
is one of 24 wards of Japan, wards of Osaka, Japan. It has an area of 8.88 km2, and a population of 60,085. It houses Osaka's financial district, as well as the Osaka Prefecture offices and principal shopping and tourist areas. Consulates Various consulates are found in Chūō-ku. The Diplomatic missions of South Korea, Consulate-General of South Korea has its own building. Three consulates, Diplomatic missions of Australia, Consulate-General of Australia, the Diplomatic missions of the Netherlands, Consulate-General of the Netherlands, and the Diplomatic missions of the Philippines, Consulate-General of the Philippines, occupy the twenty-ninth, thirty-third, and twenty-fourth floors, respectively, of the Twin21 MID Tower. The Diplomatic missions of Canada, Consulate-General of Canada is on the twelfth floor of the Daisan Shoho Building in Chūō-ku. The Diplomatic missions of France, Consulate-General of France is on the tenth floor of the Crystal Tower. The Diplomati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nikkei 225
The Nikkei 225, or , more commonly called the ''Nikkei'' or the ''Nikkei index'' (), is a stock market index for the Tokyo Stock Exchange (TSE). It is a price-weighted index, operating in the Japanese yen, Japanese Yen (JP¥), and its components are reviewed twice a year. The Nikkei 225 measures the performance of 225 highly capitalised and liquid publicly owned companies in Japan from a wide array of industry sectors. Since 2017, the index is calculated every five seconds. It was originally launched by the Tokyo Stock Exchange in 1950, and was taken over by the ''The Nikkei, Nihon Keizai Shimbun'' (''The Nikkei'') newspaper in 1950 in Japan, 1970, when the Tokyo Exchange switched to the TOPIX, Tokyo Stock Price Index (TOPIX), which is weighed by market capitalisation rather than stock prices. History The Nikkei 225 began to be calculated on 7 September 1950, retroactively calculated back to 16 May 1949, when the average price of its component stocks was 176.21 yen. Since July ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ranbaxy Pharmaceuticals
Ranbaxy Laboratories Limited was an Indian multinational pharmaceutical company that was incorporated in India in 1961 and remained an entity until 2014. The company went public in 1973. Ownership of Ranbaxy changed twice over the course of its history. In 2008, Japanese pharmaceutical company Daiichi Sankyo acquired a controlling share in Ranbaxy and in 2014, Sun Pharma acquired 100% of Ranbaxy in an all-stock deal. The Sun Pharma acquisition brought all new management to Ranbaxy, which had been laden with controversy . Sun is the world's fifth largest specialty generic pharmaceutical company. History Formation Ranbaxy was started by Ranbir Singh and Gurbax Singh in 1937 as a distributor for Japanese company Shionogi. The name Ranbaxy blends the names of its founders: Ranbir and Gurbax. Bhai Mohan Singh bought the company in 1952 from his cousins Ranbir and Gurbax. After Bhai Mohan Singh's son Parvinder Singh joined the company in 1967, the company saw an increase in scale. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antimicrobial Resistance
Antimicrobial resistance (AMR or AR) occurs when microbes evolve mechanisms that protect them from antimicrobials, which are drugs used to treat infections. This resistance affects all classes of microbes, including bacteria (antibiotic resistance), viruses (antiviral resistance), Parasitic disease, parasites (antiparasitic resistance), and fungi (antifungal resistance). Together, these adaptations fall under the AMR umbrella, posing significant challenges to healthcare worldwide. Misuse and improper management of antimicrobials are primary drivers of this resistance, though it can also occur naturally through genetic mutations and the spread of resistant genes. Antibiotic resistance, a significant AMR subset, enables bacteria to survive antibiotic treatment, complicating infection management and treatment options. Resistance arises through spontaneous mutation, horizontal gene transfer, and increased selective pressure from Antibiotic misuse, antibiotic overuse, both in medicin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rosuvastatin
Rosuvastatin, sold under the brand name Crestor among others, is a statin medication, used to prevent cardiovascular disease in those at high risk and treat dyslipidemia, abnormal lipids. It is recommended to be used with dietary changes, exercise, and weight loss. It is taken Oral administration, orally (by mouth). Common side effects include abdominal pain, nausea, headaches, and myalgia, muscle pains. Serious side effects may include rhabdomyolysis, liver problems, and diabetes. Use during pregnancy may harm the baby. Like all statins, rosuvastatin works by inhibiting HMG-CoA reductase, an enzyme found in the liver that plays a role in producing cholesterol. Rosuvastatin was patented in 1991 and approved for medical use in the United States in 2003. It is available as a generic medication. In 2022, it was the thirteenth most commonly prescribed medication in the United States, with more than 37million prescriptions. In Australia, it was one of the top 10 most prescribed m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Loratadine
Loratadine, sold under the brand name Claritin among others, is a medication used to treat allergies. This includes allergic rhinitis (hay fever) and hives. It is also available in drug combinations such as loratadine/pseudoephedrine, in which it is combined with pseudoephedrine, a nasal decongestant. It is taken orally. Common side effects include sleepiness, dry mouth, and headache. Serious side effects are rare and include allergic reactions, seizures, and liver problems. Use during pregnancy appears to be safe but has not been well studied. It is not recommended in children less than two years old. It is in the second-generation antihistamine family of medications. Loratadine was patented in 1980 and came to market in 1988. It is on the World Health Organization's List of Essential Medicines. Loratadine is available as a generic medication. In the United States, it is available over the counter. In 2022, it was the 72nd most commonly prescribed medication in the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antiseptic
An antiseptic ( and ) is an antimicrobial substance or compound that is applied to living tissue to reduce the possibility of sepsis, infection, or putrefaction. Antiseptics are generally distinguished from ''antibiotics'' by the latter's ability to safely destroy bacteria within the body, and from ''disinfectants'', which destroy microorganisms found on non-living objects. Antibacterials include antiseptics that have the proven ability to act against bacteria. Microbicides which destroy virus particles are called viricides or antivirals. Antifungals, also known as antimycotics, are pharmaceutical fungicides used to treat and prevent mycosis (fungal infection). Surgery Antiseptic practices evolved in the 19th century through multiple individuals. Ignaz Semmelweis showed already in 1847-1848 that hand washing prior to delivery reduced puerperal fever. Despite this, many hospitals continued to practice surgery in unsanitary conditions, with some surgeons taking pride in t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Moxifloxacin
Moxifloxacin is an antibiotic, used to treat bacterial infections, including pneumonia, conjunctivitis, endocarditis, tuberculosis, and sinusitis. It can be given by mouth, by injection into a vein, and as an eye drop. Common side effects include diarrhea, dizziness, and headache. Severe side effects may include spontaneous tendon ruptures, nerve damage, and worsening of myasthenia gravis. Safety of use in pregnancy and breastfeeding is unclear. Moxifloxacin is in the fluoroquinolone family of medications. It usually kills bacteria by blocking their ability to duplicate DNA. Moxifloxacin was patented in 1988 and approved for use in the United States in 1999. It is on the World Health Organization's List of Essential Medicines. In 2022, it was the 273rd most commonly prescribed medication in the United States, with more than 800,000 prescriptions. Medical uses Moxifloxacin treats a number of infections, including respiratory-tract infections, bubonic plague, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nikkei Inc
Nikkei can refer to: *, abbreviated , Nikkei, a large media corporation in Japan *, abbreviated , Nikkei, a major business newspaper published in Japan *, a Japanese stock market index, published by ''Nihon Keizai Shimbun'' * Nikkei cuisine, a Japanese Peruvian fusion cuisine that was created by the Japanese immigrants that came to Peru *, often simply ''Nikkei,'' people in the Japanese diaspora *, a Japanese-language newspaper published in São Paulo, Brazil {{disambig ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Osaka Securities Exchange
, renamed from , is the largest derivatives exchange in Japan, in terms of amount of business handled. , the Osaka Securities Exchange had 477 listed companies with a combined market capitalization of $212 billion. The Nikkei 225 Futures, introduced at the Osaka Securities Exchange in 1988, is now an internationally recognized futures index. In contrast to the Tokyo Stock Exchange, which mainly deals in spot trading, the Osaka Securities Exchange's strength is in derivative products. The OSE is the leading Derivatives Exchange in Japan and it was the largest futures market in the world in 1990 and 1991. According to statistics from 2003, the Osaka Securities Exchange handled 59% of the stock price index futures market in Japan, and almost 100% of trading in the options market. Osaka Securities Exchange Co., which listed on its Hercules market for startups in April 2004 is the only Japanese securities exchange which went public on its own market. History The birthplace for fu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
