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Shankar Balasubramanian
Sir Shankar Balasubramanian (born 30 September 1966) is an Indian-born British chemist and Herchel Smith Professor of Medicinal Chemistry in the Department of Chemistry at the University of Cambridge, ccessed 4 April 2013 Senior Group Leader at the Cancer Research UK Cambridge Institute and Fellow of Trinity College, Cambridge. He is recognised for his contributions in the field of nucleic acids. He is scientific founder of Solexa and biomodal (formally Cambridge Epigenetix). Education Born in Madras (now Chennai) India in 1966, Shankar Balasubramanian moved to the UK with his parents in 1967. He grew up in a rural area just outside Runcorn, Cheshire, and attended Daresbury Primary School, then Appleton Hall High School (which has since amalgamated to form Bridgewater High School). He went on to study the Natural Sciences Tripos at Fitzwilliam College, Cambridge, where he did his undergraduate degree from 1985 to 1988 and continued with a PhD for research on the reaction mech ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Professor
Professor (commonly abbreviated as Prof.) is an Academy, academic rank at university, universities and other tertiary education, post-secondary education and research institutions in most countries. Literally, ''professor'' derives from Latin as a 'person who professes'. Professors are usually experts in their field and teachers of the highest rank. In most systems of List of academic ranks, academic ranks, "professor" as an unqualified title refers only to the most senior academic position, sometimes informally known as "full professor". In some countries and institutions, the word ''professor'' is also used in titles of lower ranks such as associate professor and assistant professor; this is particularly the case in the United States, where the unqualified word is also used colloquially to refer to associate and assistant professors as well, and often to instructors or lecturers. Professors often conduct original research and commonly teach undergraduate, Postgraduate educa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cancer Research UK
Cancer Research UK (CRUK) is the world's largest independent cancer research organisation. It is registered as a charity in the United Kingdom and Isle of Man, and was formed on 4 February 2002 by the merger of The Cancer Research Campaign and the Imperial Cancer Research Fund. Cancer Research UK conducts research using both its own staff and grant-funded researchers. It also provides information about cancer and runs campaigns aimed at raising awareness and influencing public policy. The organisation's work is almost entirely funded by the public. It raises money through donations, legacies, community fundraising, events, retail and corporate partnerships. Over 25,000 people are regular volunteers. History The Imperial Cancer Research Fund (ICRF) was founded in 1902 as the Cancer Research Fund, changing its name to the Imperial Cancer Research Fund in 1904. It grew over the next twenty years to become one of the world's leading cancer research charities. Its executive committ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bridgewater High School (Warrington)
Bridgewater High School is a coeducational secondary school, located over two sites in Appleton, Warrington, Cheshire. The current principal is Keiron Powell, with Tracey Hatton as Head Teacher. The school day runs from 8:40 A.M. to 3:10 P.M. and uses a 5 period structure. History The school was formed in 1987 by the amalgamation of Appleton Hall County Grammar School and Stockton Heath County High School. Appleton Hall became the new school's Lower Site, while Stockton Heath (known locally as Broomfields after the attached leisure centre) became the Upper Site. The school previously held specialist Arts College status with additional specialisms in Science and Maths. It consistently achieves good GCSE results. The most recent OFSTED inspection judged the school to be Good. The school converted to academy status on 1 December 2014, and is now part of the multi-academy trust TCAT (The Challenge Academy Trust). Banding system The pupils are split into two bands, Stockton a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cheshire
Cheshire ( ) is a Ceremonial counties of England, ceremonial county in North West England. It is bordered by Merseyside to the north-west, Greater Manchester to the north-east, Derbyshire to the east, Staffordshire to the south-east, and Shropshire to the south; to the west it is bordered by the Welsh counties of Flintshire and Wrexham County Borough, Wrexham, and has a short coastline on the Dee Estuary. The largest settlement is Warrington. The county has an area of and had a population of 1,095,500 at the 2021 United Kingdom census, 2021 census. The areas around the River Mersey in the north of the county are the most densely populated, with Warrington, Runcorn, Widnes, and Ellesmere Port located on the river. The city of Chester lies in the west of the county, Crewe in the south, and Macclesfield in the east. For Local government in England, local government purposes Cheshire comprises four Unitary authorities of England, unitary authority areas: Cheshire East, Cheshire We ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Runcorn
Runcorn is an industrial town and Runcorn Docks, cargo port in the Borough of Halton, Cheshire, England. Runcorn is on the south bank of the River Mersey, where the estuary narrows to form the Runcorn Gap. It is upstream from the port of Liverpool. The Runcorn built-up area had a population of 61,145 at the 2021 United Kingdom census, 2021 census. Runcorn was founded by Æthelflæd, Æthelflæd of Mercia in 915 AD as a fortification to guard against Viking invasion at a narrowing of the River Mersey. Under Norman rule, Runcorn fell under the Halton (barony), Barony of Halton, and an Augustinians, Augustinian abbey was established there in 1115. It remained a small, isolated settlement until the Industrial Revolution, when the extension of the Bridgewater Canal to Runcorn in 1776 established it as a Port of Runcorn, port that would link Liverpool with inland Manchester and Staffordshire. and The docks enabled the growth of industry, initially shipwrights and sandstone quarries ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
India
India, officially the Republic of India, is a country in South Asia. It is the List of countries and dependencies by area, seventh-largest country by area; the List of countries by population (United Nations), most populous country since 2023; and, since its independence in 1947, the world's most populous democracy. Bounded by the Indian Ocean on the south, the Arabian Sea on the southwest, and the Bay of Bengal on the southeast, it shares land borders with Pakistan to the west; China, Nepal, and Bhutan to the north; and Bangladesh and Myanmar to the east. In the Indian Ocean, India is near Sri Lanka and the Maldives; its Andaman and Nicobar Islands share a maritime border with Thailand, Myanmar, and Indonesia. Modern humans arrived on the Indian subcontinent from Africa no later than 55,000 years ago., "Y-Chromosome and Mt-DNA data support the colonization of South Asia by modern humans originating in Africa. ... Coalescence dates for most non-European populations averag ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Madras
Chennai, also known as Madras ( its official name until 1996), is the capital and largest city of Tamil Nadu, the southernmost state of India. It is located on the Coromandel Coast of the Bay of Bengal. According to the 2011 Indian census, Chennai is the sixth-most-populous city in India and forms the fourth-most-populous urban agglomeration. Incorporated in 1688, the Greater Chennai Corporation is the oldest municipal corporation in India and the second oldest in the world after London. Historically, the region was part of the Chola, Pandya, Pallava and Vijayanagara kingdoms during various eras. The coastal land which then contained the fishing village Madrasapattinam, was purchased by the British East India Company from the Nayak ruler Chennapa Nayaka in the 17th century. The British garrison established the Madras city and port and built Fort St. George, the first British fortress in India. The city was made the winter capital of the Madras Presidency, a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Companies House
Companies House is the executive agency of the British Government that maintains the Company register, register of companies, employs the company registrars and is responsible for Incorporation (business), incorporating all forms of Company, companies in the United Kingdom. Prior to 1844, no central company register existed and Company, companies could only be Incorporation (business), incorporated through letters patent and Act of Parliament (UK), legislation. At the time, few incorporated companies existed; between 1801 and 1844, only about 100 companies were incorporated. The Joint Stock Companies Act 1844 created a centralised register of companies, enabled companies to be incorporated by registration, and established the office of the registrar; the Joint Stock Companies Act 1856 mandated separate registrars for each of the three Jurisdictions of the United Kingdom, UK jurisdictions. Initially just a brand, Companies House became an official executive agency in 1988. All P ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nucleic Acid
Nucleic acids are large biomolecules that are crucial in all cells and viruses. They are composed of nucleotides, which are the monomer components: a pentose, 5-carbon sugar, a phosphate group and a nitrogenous base. The two main classes of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). If the sugar is ribose, the polymer is RNA; if the sugar is deoxyribose, a variant of ribose, the polymer is DNA. Nucleic acids are chemical compounds that are found in nature. They carry information in cells and make up genetic material. These acids are very common in all living things, where they create, encode, and store information in every living cell of every outline of life forms, life-form on Earth. In turn, they send and express that information inside and outside the cell nucleus. From the inner workings of the cell to the young of a living thing, they contain and provide information via the nucleic acid sequence. This gives the RNA and DNA their unmistakable 'la ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Department Of Chemistry, University Of Cambridge
The Yusuf Hamied Department of Chemistry is the University of Cambridge's chemistry department. It was formed from a merger in the early 1980s of two separate departments that had moved into the Lensfield Road building decades earlier: the Department of Physical Chemistry (originally led by Professor Ronald Norrish FRS, Nobel Laureate; the department was previously located near the Old Cavendish in Free School Lane - see photo) and the Department of Chemistry (that included theoretical chemistry and which was led by Lord (Alexander) Todd FRS, Nobel Laureate) respectively. Research interests in the department cover a broad of chemistry ranging from molecular biology to geophysics. The department is located on the Lensfield Road, next to the Panton Arms on the South side of Cambridge. In December 2020, it was renamed for 30 years in recognition of a donation from Dr Yusuf Hamied, an alumnus of the department. Research The Department's research is organised around five Research ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
DNA Sequencing
DNA sequencing is the process of determining the nucleic acid sequence – the order of nucleotides in DNA. It includes any method or technology that is used to determine the order of the four bases: adenine, thymine, cytosine, and guanine. The advent of rapid DNA sequencing methods has greatly accelerated biological and medical research and discovery. Knowledge of DNA sequences has become indispensable for basic biological research, Genographic Project, DNA Genographic Projects and in numerous applied fields such as medical diagnosis, biotechnology, forensic biology, virology and biological systematics. Comparing healthy and mutated DNA sequences can diagnose different diseases including various cancers, characterize antibody repertoire, and can be used to guide patient treatment. Having a quick way to sequence DNA allows for faster and more individualized medical care to be administered, and for more organisms to be identified and cataloged. The rapid advancements in DNA seque ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
G-quadruplex
In molecular biology, G-quadruplex secondary structures (G4) are formed in nucleic acids by sequences that are rich in guanine. They are helical in shape and contain guanine tetrads that can form from one, two or four strands. The unimolecular forms often occur naturally near the ends of the chromosomes, better known as the telomeric regions, and in transcriptional regulatory regions of multiple genes, both in microbes and across vertebrates including oncogenes in humans. Four guanine bases can associate through Hoogsteen hydrogen bonding to form a square planar structure called a guanine tetrad (G-tetrad or G-quartet), and two or more guanine tetrads (from G-tracts, continuous runs of guanine) can stack on top of each other to form a G-quadruplex. The placement and bonding to form G-quadruplexes is not random and serve very unusual functional purposes. The quadruplex structure is further stabilized by the presence of a cation, especially potassium, which sits in a centr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
