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Serafim Guimarães
Serafim Guimarães, full name Serafim Correia Pinto Guimarães, (born May 2, 1934) is a Portuguese physician and pharmacology, pharmacologist. With his colleague Walter Osswald (born 1928) he made the Department of Pharmacology, Medical Faculty of the University of Porto, a center of research on catecholamines and the sympathetic nervous system, especially their relation to blood vessels. Life Guimarães was born in Espargo, a village close to the city of Santa Maria da Feira in the Portuguese Norte Region, Portugal, Região Norte. He is the second son of the peasant Américo Ferreira Pinto Guimarães and his wife Maria Emília Correia née Pais. Serafim studied medicine at the University of Porto and simultaneously worked at the Department of Pharmacology. After military service in Angola from November 1963 to December 1965 he returned to the Department of Pharmacology. In 1966 he spent five months with Hans-Joachim Schümann at the University of Duisburg-Essen, in 1971 and 197 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Prof
Jacob Lukas Anderson (born April 29, 1984), better known by his stage name Prof, is an American rapper, singer, and producer based in Minneapolis, Minnesota. He released his first full-length album, ''Project Gampo'', in 2007 and has since released six additional albums and three EPs. In 2012, ''City Pages'' named Prof on their list of Minnesota's 20 best rappers. He was formerly signed to Rhymesayers Entertainment. Early life Jacob "Jake" Anderson was born in Minneapolis, Minnesota, and grew up in the city's Powderhorn, Minneapolis, Powderhorn neighborhood. His mother, Colleen, had a rocky relationship with his father (who suffered from bipolar disorder and was physically abusive) whom she would later divorce and move away from, taking Anderson's three older sisters with her. In his teenage years, he developed a "comedic, dirty-mouthed rap persona" he named Gampo after a childhood friend. Anderson graduated from South High School (Minneapolis), Minneapolis South High School in 2 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Adrenoceptor
The adrenergic receptors or adrenoceptors are a class of G protein-coupled receptors that are targets of many catecholamines like norepinephrine (noradrenaline) and epinephrine (adrenaline) produced by the body, but also many medications like beta blockers, beta-2 (β2) agonists and alpha-2 (α2) agonists, which are used to treat high blood pressure and asthma, for example. Many cells have these receptors, and the binding of a catecholamine to the receptor will generally stimulate the sympathetic nervous system (SNS). The SNS is responsible for the fight-or-flight response, which is triggered by experiences such as exercise or fear-causing situations. This response dilates pupils, increases heart rate, mobilizes energy, and diverts blood flow from non-essential organs to skeletal muscle. These effects together tend to increase physical performance momentarily. History By the turn of the 19th century, it was agreed that the stimulation of sympathetic nerves could cause dif ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Noradrenaline
Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and body as a hormone, neurotransmitter and neuromodulator. The name "noradrenaline" (from Latin '' ad'', "near", and '' ren'', "kidney") is more commonly used in the United Kingdom and the rest of the world, whereas "norepinephrine" (from Ancient Greek ἐπῐ́ (''epí''), "upon", and νεφρός (''nephrós''), "kidney") is usually preferred in the United States. "Norepinephrine" is also the international nonproprietary name given to the drug. Regardless of which name is used for the substance itself, parts of the body that produce or are affected by it are referred to as noradrenergic. The general function of norepinephrine is to mobilize the brain and body for action. Norepinephrine release is lowest during sleep, rises during wakefulness, and reaches much higher levels during situations of stress or danger, in the so ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Adrenaline
Adrenaline, also known as epinephrine, is a hormone and medication which is involved in regulating visceral functions (e.g., respiration). It appears as a white microcrystalline granule. Adrenaline is normally produced by the adrenal glands and by a small number of neurons in the medulla oblongata. It plays an essential role in the fight-or-flight response by increasing blood flow to muscles, heart output by acting on the SA node, pupil dilation response, and blood sugar level. It does this by binding to alpha and beta receptors. It is found in many animals, including humans, and some single-celled organisms. It has also been isolated from the plant '' Scoparia dulcis'' found in Northern Vietnam. Medical uses As a medication, it is used to treat several conditions, including allergic reaction anaphylaxis, cardiac arrest, and superficial bleeding. Inhaled adrenaline may be used to improve the symptoms of croup. It may also be used for asthma when other treatments a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Artery
An artery () is a blood vessel in humans and most other animals that takes oxygenated blood away from the heart in the systemic circulation to one or more parts of the body. Exceptions that carry deoxygenated blood are the pulmonary arteries in the pulmonary circulation that carry blood to the lungs for oxygenation, and the umbilical arteries in the fetal circulation that carry deoxygenated blood to the placenta. It consists of a multi-layered artery wall wrapped into a tube-shaped channel. Arteries contrast with veins, which carry deoxygenated blood back towards the heart; or in the pulmonary and fetal circulations carry oxygenated blood to the lungs and fetus respectively. Structure The anatomy of arteries can be separated into gross anatomy, at the macroscopic scale, macroscopic level, and histology, microanatomy, which must be studied with a microscope. The arterial system of the human body is divided into systemic circulation, systemic arteries, carrying blood from the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vein
Veins () are blood vessels in the circulatory system of humans and most other animals that carry blood towards the heart. Most veins carry deoxygenated blood from the tissues back to the heart; exceptions are those of the pulmonary and fetal circulations which carry oxygenated blood to the heart. In the systemic circulation, arteries carry oxygenated blood away from the heart, and veins return deoxygenated blood to the heart, in the deep veins. There are three sizes of veins: large, medium, and small. Smaller veins are called venules, and the smallest the post-capillary venules are microscopic that make up the veins of the microcirculation. Veins are often closer to the skin than arteries. Veins have less smooth muscle and connective tissue and wider internal diameters than arteries. Because of their thinner walls and wider lumens they are able to expand and hold more blood. This greater capacity gives them the term of ''capacitance vessels''. At any time, nearly 70% o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
History Of Catecholamine Research
The catecholamines are a group of neurotransmitters composed of the endogenous substances dopamine, noradrenaline (norepinephrine), and adrenaline (epinephrine), as well as numerous artificially synthesized compounds such as isoprenaline - an anti-bradycardiac medication. Their investigation constitutes a major chapter in the history of physiology, biochemistry, and pharmacology. Adrenaline was the first hormone extracted from an endocrine gland and obtained in pure form, before the word ''hormone'' was coined. Adrenaline was also the first hormone whose structure and biosynthesis was discovered. Second to acetylcholine, adrenaline and noradrenaline were some of the first neurotransmitters discovered, and the first intercellular biochemical signals to be found in intracellular vesicles. The β-adrenoceptor gene was the first G protein-coupled receptor to be cloned. Adrenaline in the Adrenal Medulla Forerunners British physician and physiologist Henry Hyde Salter (1823–18 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
British Journal Of Pharmacology
The ''British Journal of Pharmacology'' is a biweekly peer-reviewed medical journal covering all aspects of experimental pharmacology. It is published for the British Pharmacological Society by Wiley-Blackwell. It was established in 1946 as the ''British Journal of Pharmacology and Chemotherapy,'' and originally published by the British Medical Association. The journal obtained its current title in 1968, when the journal moved publisher to Macmillan. It has been published by Wiley-Blackwell since 2009. The current editor-in-chief is Péter Ferdinandy. Previous editors-in-chief include Amrita Ahluwalia, Ian McGrath, Humphrey Rang, Alan North, Phil Moore, Bill Large, and Tony Birmingham. A sister journal, also published for the British Pharmacological Society by Wiley-Blackwell, is the ''British Journal of Clinical Pharmacology''. The journal publishes research papers, review articles, commentaries and correspondence in all fields of pharmacology. It also publishes themed issues, a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Adrenergic Receptor
The adrenergic receptors or adrenoceptors are a class of G protein-coupled receptors that are targets of many catecholamines like norepinephrine (noradrenaline) and epinephrine (adrenaline) produced by the body, but also many medications like beta blockers, beta-2 (β2) agonists and alpha-2 (α2) agonists, which are used to treat high blood pressure and asthma, for example. Many cells have these receptors, and the binding of a catecholamine to the receptor will generally stimulate the sympathetic nervous system (SNS). The SNS is responsible for the fight-or-flight response, which is triggered by experiences such as exercise or fear-causing situations. This response dilates pupils, increases heart rate, mobilizes energy, and diverts blood flow from non-essential organs to skeletal muscle. These effects together tend to increase physical performance momentarily. History By the turn of the 19th century, it was agreed that the stimulation of sympathetic nerves could cause ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Serafim Guimaraes Trendelenburg
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Serafim may refer to: * ''Serafim, the Lighthouse Keeper's Son'', a Croatian film * Serafim (given name), a masculine given name * Dimitrie Serafim (1862–1931), Romanian painter * Leon Serafim (born 1945), American academic and japanologist * Matheus Serafim (born 1998), Brazilian footballer * Le Sserafim, a South Korean girl group See also * Serafin (other) * Seraphim (other) A seraph is a celestial being in Jewish and Christian mythology. Seraph(s) or seraphim may also refer to: Arts and entertainment Film * Seraph (The Matrix), Seraph (''The Matrix''), a character in ''The Matrix'' film trilogy Games * Seraph, chara ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Full Professor
Professor (commonly abbreviated as Prof.) is an academic rank at universities and other post-secondary education and research institutions in most countries. Literally, ''professor'' derives from Latin as a 'person who professes'. Professors are usually experts in their field and teachers of the highest rank. In most systems of academic ranks, "professor" as an unqualified title refers only to the most senior academic position, sometimes informally known as "full professor". In some countries and institutions, the word ''professor'' is also used in titles of lower ranks such as associate professor and assistant professor; this is particularly the case in the United States, where the unqualified word is also used colloquially to refer to associate and assistant professors as well, and often to instructors or lecturers. Professors often conduct original research and commonly teach undergraduate, postgraduate, or professional courses in their fields of expertise. In universiti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
