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SF3B6
Splicing factor 3B subunit 6, is a protein encoded by ''SF3B6'' gene in vertebrates. Function This gene encodes a 14 kDa protein subunit of the splicing factor 3b protein complex, complex. Splicing factor 3b associates with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. This 14 kDa protein interacts directly with subunit 1 of the splicing factor 3b complex. This 14 kDa protein also interacts directly with the adenosine that carries out the first transesterification step of splicing at the pre-mRNA branch site. Interactions SF3B14 has been shown to Protein-protein interaction, interact with SF3B1. References Further reading * * * * * * * * * * * {{Gene-2-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Splicing Factor 3b
A splicing factor is a protein involved in the removal of introns from strings of messenger RNA, so that the exons can bind together; the process takes place in particles known as spliceosomes. Splicing factors regulate the binding of the snRNPs U1 and U2 to the 3' and 5' ends of the intron during splicing and can either be splicing promoters or splicing repressors. In a research paper, splicing factors were found to be produced upon application of resveratrol analogues, which induced senescent cells to rejuvenate. The expression of splicing factors may be altered during aging. Splicing factor 3b Splicing factor 3b is a protein complex consisting of the following proteins: PHF5A, SF3B1, SF3B2, SF3B3, SF3B4 Splicing factor 3B subunit 4 is a protein that in humans is encoded by the ''SF3B4'' gene. Function This gene encodes one of four subunits of the splicing factor 3b. The protein encoded by this gene cross-links to a region in the pre-mRNA imm ..., SF3B5, SF3B6. No ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |