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Rutin
Rutin, also called rutoside, quercetin-3-O-rutinoside and sophorin, is the glycoside combining the flavonol quercetin and the disaccharide rutinose (α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranose). It is a flavonoid found in a wide variety of plants, including citrus. Occurrences Rutin is one of the phenolic compounds found in the invasive plant species, '' Carpobrotus edulis''. Its name comes from the name of '' Ruta graveolens'', a plant that also contains rutin. Various citrus fruit peels contain 32 to 49 mg/g of flavonoids expressed as rutin equivalents. Citrus leaves contain rutin at concentrations of 11 and 7 g/kg in orange and lime trees, respectively. In 2021, Samoan researchers identified rutin in the native plant, ''matalafi'' (''Psychotria insularum''). Metabolism The enzyme quercitrinase found in ''Aspergillus flavus'' is in the rutin catabolic pathway. In food Rutin is a citrus flavonoid glycoside found in many plants, including buckwheat, the leaves and ...
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Quercetin
Quercetin is a plant flavonol from the flavonoid group of polyphenols. It is found in many fruits, vegetables, leaves, seeds, and grains; capers, red onions, and kale are common foods containing appreciable amounts of it. It has a bitter flavor and is used as an ingredient in dietary supplements, beverages, and foods. Occurrence Quercetin is a flavonoid widely distributed in nature. The name has been used since 1857, and is derived from ''quercetum'' (oak forest), after the oak genus ''Quercus''. It is a naturally occurring polar auxin transport inhibitor. Quercetin is one of the most abundant dietary flavonoids, with an average daily consumption of 25–50 milligrams. In red onions, higher concentrations of quercetin occur in the outermost rings and in the part closest to the root, the latter being the part of the plant with the highest concentration. One study found that organically grown tomatoes had 79% more quercetin than non-organically grown fruit. Quercetin is pres ...
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Glycoside
In chemistry, a glycoside is a molecule in which a sugar is bound to another functional group via a glycosidic bond. Glycosides play numerous important roles in living organisms. Many plants store chemicals in the form of inactive glycosides. These can be activated by enzyme hydrolysis, which causes the sugar part to be broken off, making the chemical available for use. Many such plant glycosides are used as medications. Several species of ''Heliconius'' butterfly are capable of incorporating these plant compounds as a form of chemical defense against predators. In animals and humans, poisons are often bound to sugar molecules as part of their elimination from the body. In formal terms, a glycoside is any molecule in which a sugar group is bonded through its anomeric carbon to another group via a glycosidic bond. Glycosides can be linked by an O- (an '' O-glycoside''), N- (a '' glycosylamine''), S-(a '' thioglycoside''), or C- (a '' C-glycoside'') glycosidic bond. Accordin ...
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Tartary Buckwheat
''Fagopyrum tataricum'', also known as Tartary buckwheat, green buckwheat, ku qiao, Tatar buckwheat, or bitter buckwheat, is a domesticated food plant in the genus ''Fagopyrum'' in the family Polygonaceae. With another species in the same genus, common buckwheat, it is often counted as a cereal, but the buckwheats are not closely related to true cereals. Tartary buckwheat is more bitter and contains more rutin than common buckwheat. It also contains other bioactive components such as flavonoids, phenolic acids, 2-hydroxybenzylamine and quercitrin. Tartary buckwheat was domesticated in East Asia and is also cultivated in Europe and North America. While it is an unfamiliar food in the West, it is common in the Himalayan region today, as well as other regions in Southwest China such as Sichuan province. The plant has been cultivated in many parts of the world; however, when found among other crops it is considered a weed. Chemistry ''Fagopyrum tataricum'' contains aromatic ...
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Buckwheat
Buckwheat (''Fagopyrum esculentum''), or common buckwheat, is a flowering plant in the knotweed family Polygonaceae cultivated for its grain-like seeds and as a cover crop. The name "buckwheat" is used for several other species, such as ''Fagopyrum tataricum'', a domesticated food plant raised in Asia. Despite its name, buckwheat is not closely related to wheat. It is not a cereal, nor is it even a member of the Poaceae, grass family. Buckwheat is related to sorrel, Polygonum, knotweed, and rhubarb, and is known as a pseudocereal because its seeds' culinary use is the same as cereals, owing to their high starch content. Etymology The name "buckwheat" or "beech wheat" comes from its triangular seeds, which resemble the much larger seeds of the beech nut from the beech, beech tree, and the fact that it is used like wheat. The word may be a translation of Middle Dutch ''boecweite'': ''boec'' (Modern Dutch ''beuk''), "beech" (see Proto-Indo-European language, PIE *''bhago''-) and ...
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Quercitrinase
In enzymology, a quercitrinase () is an enzyme that catalyzes the chemical reaction :quercitrin + H2O \rightleftharpoons L-rhamnose + quercetin Thus, the two substrates of this enzyme are quercitrin and H2O, whereas its two products are L- rhamnose and quercetin. This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is quercitrin 3-L-rhamnohydrolase. The enzyme can be found in ''Aspergillus flavus''. It is an enzyme in the rutin Rutin, also called rutoside, quercetin-3-O-rutinoside and sophorin, is the glycoside combining the flavonol quercetin and the disaccharide rutinose (α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranose). It is a flavonoid found in a wide variety of pl ... catabolic pathway. References Further reading * EC 3.2.1 Enzymes of unknown structure Quercetin glycosides {{3.2-enzyme-stub ...
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Asparagus
Asparagus, or garden asparagus, folk name sparrow grass, scientific name ''Asparagus officinalis'', is a perennial flowering plant species in the genus '' Asparagus''. Its young shoots are used as a spring vegetable. It was once classified in the lily family, like the related ''Allium'' species, onions and garlic. However, genetic research places lilies, ''Allium'', and asparagus in three separate families—the Liliaceae, Amaryllidaceae, and Asparagaceae, respectively— the Amaryllidaceae and Asparagaceae are grouped together in the order Asparagales. Sources differ as to the native range of ''Asparagus officinalis'', but generally include most of Europe and western temperate Asia. It is widely cultivated as a vegetable crop. Description Asparagus is a herbaceous, perennial plant growing to tall, with stout stems with much-branched, feathery foliage. The 'leaves' are in fact needle-like cladodes ( modified stems) in the axils of scale leaves; they are long an ...
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Psychotria Insularum
''Psychotria insularum'' is a rainforest understory shrub from the coffee family, Rubiaceae. Its native range is the South Pacific. It has traditional uses in herbal medicine. In 2021, the potent anti-inflammatory rutin was isolated from ''P. insularum'' (known in Samoa Samoa, officially the Independent State of Samoa; sm, Sāmoa, and until 1997 known as Western Samoa, is a Polynesian island country consisting of two main islands ( Savai'i and Upolu); two smaller, inhabited islands ( Manono and Apolima); ... as "matalafi"). References Flora of Brazil insularum Taxa named by John Edward Gray {{Rubiaceae-stub ...
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Carpobrotus Edulis
''Carpobrotus edulis'' is a ground-creeping plant with succulent leaves in the genus ''Carpobrotus'', native to South Africa. Its common names include hottentot-fig, sour fig, ice plant or highway ice plant. Description ''Carpobrotus edulis'' is a creeping, mat-forming succulent species. It grows year round, with individual shoot segments growing more than 1 m (3 ft) per year. It can grow to at least 50 m (165 ft) in diameter. The leaves are a dull-green or yellow-green colour. They are only very slightly curved and have serrated sides near the tips. The yellow flowers are produced from April to October, and range from in diameter. Two of the calyx lobes are longer, extending further than the petals. The flowers open in the morning in bright sunlight and close at night. The receptacle is somewhat wedge-shaped, tapering down to the pedicel. The fruit is multi-chambered, ripening from green to yellow. The species is easily confused with its close relatives ...
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Rutinose
Rutinose is the disaccharide also known as 6-''O''-α-L- rhamnosyl-D-glucose (C12H22O10) that is present in some flavonoid glycosides. It is prepared from rutin by hydrolysis Hydrolysis (; ) is any chemical reaction in which a molecule of water breaks one or more chemical bonds. The term is used broadly for substitution, elimination, and solvation reactions in which water is the nucleophile. Biological hydrolysi ... with the enzyme rhamnodiastase. References * Disaccharides Deoxy sugars {{organic-compound-stub ...
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Flavonoid
Flavonoids (or bioflavonoids; from the Latin word ''flavus'', meaning yellow, their color in nature) are a class of polyphenolic secondary metabolites found in plants, and thus commonly consumed in the diets of humans. Chemically, flavonoids have the general structure of a 15-carbon skeleton, which consists of two phenyl rings (A and B) and a heterocyclic ring (C, the ring containing the embedded oxygen). This carbon structure can be abbreviated C6-C3-C6. According to the IUPAC nomenclature, they can be classified into: *flavonoids or bioflavonoids * isoflavonoids, derived from 3-phenyl chromen-4-one (3-phenyl-1,4- benzopyrone) structure *neoflavonoids, derived from 4-phenyl coumarine (4-phenyl-1,2- benzopyrone) structure The three flavonoid classes above are all ketone-containing compounds and as such, anthoxanthins (flavones and flavonols). This class was the first to be termed bioflavonoids. The terms flavonoid and bioflavonoid have also been more loosely used to descri ...
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Flavonol
Flavonols are a class of flavonoids that have the 3-hydroxyflavone backbone (IUPAC name : 3-hydroxy-2-phenylchromen-4-one). Their diversity stems from the different positions of the phenolic -OH groups. They are distinct from flavanols (with "a") such as catechin, another class of flavonoids. Flavonols are present in a wide variety of fruits and vegetables. In Western populations, estimated daily intake is in the range of 20–50 mg per day for flavonols. Individual intake varies depending on the type of diet consumed. The phenomenon of dual fluorescence (due to excited state intramolecular proton transfer or ESIPT) is induced by tautomerism of flavonols (and glucosides) and could contribute to plant UV protection and flower colour. Besides being a subclass of flavonoids, flavonols are suggested by a study of cranberry juice to play a role along with proanthocyanidins, in the juice's ability to block bacterial adhesion, demonstrated by the compressing the fimbria of ...
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Chronic Venous Insufficiency
Chronic venous insufficiency (CVI) is a medical condition in which blood pools in the veins, straining the walls of the vein. The most common cause of CVI is superficial venous reflux which is a treatable condition. As functional venous valves are required to provide for efficient blood return from the lower extremities, this condition typically affects the legs. If the impaired vein function causes significant symptoms, such as swelling and ulcer formation, it is referred to as chronic venous disease. It is sometimes called ''chronic peripheral venous insufficiency'' and should not be confused with post-thrombotic syndrome in which the deep veins have been damaged by previous deep vein thrombosis. Most cases of CVI can be improved with treatments to the superficial venous system or stenting the deep system. Varicose veins for example can now be treated by local anesthetic endovenous surgery. Rates of CVI are higher in women than in men. Other risk factors include genetics, sm ...
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