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Ruslan Medzhitov
Ruslan Medzhitov (born March 12, 1966) is a professor of immunobiology and dermatology at the Yale School of Medicine, and an investigator at the Howard Hughes Medical Institute. His research focuses on the analysis of the innate immune system, inflammatory response, innate control of the adaptive immunity, and host-pathogen interactions. In 2010, he was elected to the National Academy of Sciences, and in 2017 he was named Sterling Professor. Biography Ruslan Medzhitov was born in 1966 in Tashkent. He earned a Bachelor of Science at Tashkent State University before going on to pursue a PhD in biochemistry at Moscow State University. In 1992 he read an article by Charles Janeway about a hypothetical flip-flop triggered innate immunity. Before coming to Yale, he was a fellow in the laboratory of Russell Doolittle at the University of California, San Diego. He did his post-doctoral training with Janeway at Yale University School of Medicine from 1994 to 1999. In 1997, Medzhitov ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tashkent
Tashkent (), also known as Toshkent, is the Capital city, capital and List of cities in Uzbekistan, largest city of Uzbekistan. It is the most populous city in Central Asia, with a population of more than 3 million people as of April 1, 2024. It is located in northeastern Uzbekistan, near the border with Kazakhstan. Before the influence of Islam in the mid-8th century AD, Sogdian people, Sogdian and Turkic people, Turkic culture was predominant. After Genghis Khan destroyed the city in 1219, it was rebuilt and profited from its location on the Silk Road. From the 18th to the 19th centuries, the city became an Tashkent (1784), independent city-state, before being re-conquered by the Khanate of Kokand. In 1865, Tashkent fell to the Russian Empire; as a result, it became the capital of Russian Turkestan. In Soviet Union, Soviet times, it witnessed major growth and demographic changes due to Population transfer in the Soviet Union, forced deportations from throughout the Soviet Unio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Russell Doolittle
Russell F. Doolittle (January 10, 1931 – October 11, 2019) was an American biochemist who taught at the University of California, San Diego (UCSD). Described as a "world-renowned evolutionary biologist", Doolittle's research primarily focused on the structure and evolution of proteins. Highlights of Doolittle's decades of research include his role in co-developing the hydropathy index and determining the structure of fibrinogen. Early life and education Doolittle was born on January 10, 1931, in New Haven, Connecticut. Doolittle earned a B.A. in biology from Wesleyan University in 1952, and an M.A. in education from Trinity College (Connecticut), Trinity College in 1957. He earned his Ph.D. in biochemistry at Harvard University in 1962 with research in blood clotting. Doolittle later conducted postdoctoral research in Sweden funded by the National Institutes of Health (NIH). Career Doolittle notably co-developed the hydropathy index, and was instrumental in determining t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dickson Prize
The Dickson Prize in Medicine and the Dickson Prize in Science were both established in 1969 by Joseph Z. Dickson and Agnes Fischer Dickson. Dickson Prize in Medicine The Dickson Prize in Medicine is awarded annually by the University of Pittsburgh and recognizes US citizens who have made "significant, progressive contributions" to medicine. The award includes $50,000, a bronze medal, and the Dickson Prize Lecture. Recipients SourceUniversity of Pittsburgh * 1971 Earl W. Sutherland Jr. * 1972 Solomon A. Berson and Rosalyn S. Yalow * 1973 John H. Gibbon Jr. * 1974 Stephen W. Kuffler * 1975 Elizabeth F. Neufeld * 1976 Frank J. Dixon * 1977 Roger Guillemin * 1978 Paul Greengard * 1979 Bert W. O'Malley * 1980 David H. Hubel and Torsten N. Wiesel * 1981 Philip Leder * 1982 Francis H. Ruddle * 1983 Eric R. Kandel * 1984 Solomon H. Snyder * 1985 Robert C. Gallo * 1986 J. Michael Bishop * 1987 Elvin A. Kabat * 1988 Leroy E. Hood * 1989 Bernard Moss * 1990 Ernst Knobil * ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lewis S
Lewis may refer to: Names * Lewis (given name), including a list of people with the given name * Lewis (surname), including a list of people with the surname Music * Lewis (musician), Canadian singer * " Lewis (Mistreated)", a song by Radiohead from ''My Iron Lung'' Places * Lewis (crater), a crater on the far side of the Moon * Isle of Lewis, the northern part of Lewis and Harris, Western Isles, Scotland United States * Lewis, Colorado * Lewis, Indiana * Lewis, Iowa * Lewis, Kansas * Lewis Wharf, Boston, Massachusetts * Lewis, Missouri * Lewis, Essex County, New York * Lewis, Lewis County, New York * Lewis, North Carolina * Lewis, Vermont * Lewis, Wisconsin Ships * USS ''Lewis'' (1861), a sailing ship * USS ''Lewis'' (DE-535), a destroyer escort in commission from 1944 to 1946 Science * Lewis structure, a diagram of a molecule that shows the bonding between the atoms * Lewis acids and bases * Lewis antigen system, a human blood group system * Lewis number, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Munich
The Ludwig Maximilian University of Munich (simply University of Munich, LMU or LMU Munich; ) is a public university, public research university in Munich, Bavaria, Germany. Originally established as the University of Ingolstadt in 1472 by Duke Ludwig IX of Bavaria-Landshut, it is Germany's List of universities in Germany, sixth-oldest university in continuous operation. In 1800, the university was moved from Ingolstadt to Landshut by King Maximilian I Joseph of Bavaria when the city was threatened by the French, before being transferred to its present-day location in Munich in 1826 by King Ludwig I of Bavaria. In 1802, the university was officially named Ludwig-Maximilians-Universität by King Maximilian I of Bavaria in honor of himself and Ludwig IX. LMU is currently the second-largest university in Germany in terms of student population; in the 2023/24 winter semester, the university had a total of 52,972 matriculated students. Of these, 10,138 were freshmen, while internati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Yale University School Of Medicine
The Yale School of Medicine is the medical school of Yale University, a private research university in New Haven, Connecticut. It was founded in 1810 as the Medical Institution of Yale College and formally opened in 1813. It is the sixth-oldest medical school in the United States. The school’s faculty clinical practice is Yale Medicine. Yale School of Medicine has a strong affiliation with its primary teaching hospital, Yale New Haven Hospital and the Yale New Haven Health System. The school is home to the Harvey Cushing/John Hay Whitney Medical Library, which is one of the country’s largest modern medical libraries and is known for its historical collections. The faculty includes 31 National Academy of Sciences members, 50 National Academy of Medicine members, and nine Howard Hughes Medical Institute (HHMI) investigators/professors. Yale School of Medicine faculty have also received various international awards for their scientific discoveries, impactful research, and prof ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sterling Professor
Sterling Professor, the highest academic rank at Yale University, is awarded to a Academic tenure in North America, tenured faculty member considered the best in their field. It is akin to the rank of distinguished professor at other universities. The appointment, made by the List of presidents of Yale University, President of Yale University and confirmed by the Yale Corporation, can be granted to any Yale faculty member, and up to forty professors can hold the title at the same time. The position was established through a 1918 bequest from John William Sterling, and the first Sterling Professor was appointed in 1920. History The professorships are named for and funded by a $15-million bequest left by John William Sterling, John W. Sterling, partner in the New York law firm Shearman & Sterling and an 1864 graduate of Yale College. In addition to financing the university's largest construction projects throughout the 1920s, including the Sterling Memorial Library and flagship fac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Forbes
''Forbes'' () is an American business magazine founded by B. C. Forbes in 1917. It has been owned by the Hong Kong–based investment group Integrated Whale Media Investments since 2014. Its chairman and editor-in-chief is Steve Forbes. The company is headquartered in Jersey City, New Jersey. Sherry Phillips is the current CEO of Forbes as of January 1, 2025. Published eight times per year, ''Forbes'' feature articles on finance, industry, investing, and marketing topics. It also reports on related subjects such as technology, communications, science, politics, and law. It has an international edition in Asia as well as editions produced under license in 27 countries and regions worldwide. The magazine is known for its lists and rankings, including its lists of the richest Americans (the Forbes 400, ''Forbes'' 400), of 30 notable people under the age of 30 (the Forbes 30 Under 30, ''Forbes'' 30 under 30), of America's wealthiest celebrities, of the world's top companies (the Fo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Forbes Magazine
''Forbes'' () is an American business magazine founded by B. C. Forbes in 1917. It has been owned by the Hong Kong–based investment group Integrated Whale Media Investments since 2014. Its chairman and editor-in-chief is Steve Forbes. The company is headquartered in Jersey City, New Jersey. Sherry Phillips is the current CEO of Forbes as of January 1, 2025. Published eight times per year, ''Forbes'' feature articles on finance, industry, investing, and marketing topics. It also reports on related subjects such as technology, communications, science, politics, and law. It has an international edition in Asia as well as editions produced under license in 27 countries and regions worldwide. The magazine is known for its lists and rankings, including its lists of the richest Americans (the ''Forbes'' 400), of 30 notable people under the age of 30 (the ''Forbes'' 30 under 30), of America's wealthiest celebrities, of the world's top companies (the ''Forbes'' Global 2000), of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
US National Academy Of Sciences
The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the National Academy of Medicine (NAM). As a national academy, new members of the organization are elected annually by current members, based on their distinguished and continuing achievements in original research. Election to the National Academy is one of the highest honors in the scientific field in the United States. Members of the National Academy of Sciences serve ''pro bono'' as "advisers to the nation" on science, engineering, and medicine. The group holds a congressional charter under Title 36 of the United States Code. Congress legislated and President Abraham Lincoln signed an Act of Congress (1863) establishing the National Academy of Sciences as an independent, trusted nongovernmental institution, created for the purpose of "pr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Immune Response
An immune response is a physiological reaction which occurs within an organism in the context of inflammation for the purpose of defending against exogenous factors. These include a wide variety of different toxins, viruses, intra- and extracellular bacteria, protozoa, Parasitic worm, helminths, and Fungus, fungi which could cause serious problems to the health of the host organism if not cleared from the body. In addition, there are other forms of immune response. For example, harmless exogenous factors (such as pollen and food components) can trigger allergy; latex and metals are also known allergens. A transplanted tissue (for example, blood) or organ can cause graft-versus-host disease. A type of immune reactivity known as Rh disease can be observed in pregnant women. These special forms of immune response are classified as hypersensitivity. Another special form of immune response is CD4+ T cells and antitumor immunity, antitumor immunity. In general, there are two branches of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
TLR4
Toll-like receptor 4 (TLR4), also designated as CD284 (cluster of differentiation 284), is a key activator of the innate immune response and plays a central role in the fight against bacterial infections. TLR4 is a transmembrane protein of approximately 95 kDa that is encoded by the ''TLR4'' gene. TLR4 belongs to the toll-like receptor family which is representative of the pattern recognition receptors (PRR), so named for their ability to recognize evolutionarily conserved components of microorganisms (bacteria, viruses, fungi and parasites) called pathogen-associated molecular patterns (PAMPs). The recognition of a PAMP by a PRR triggers rapid activation of the innate immunity essential to fight infectious diseases. TLR4 is expressed in immune cells mainly of myeloid origin, including monocytes, macrophages and dendritic cells (DC). It is also expressed at a lower level on some non-immune cells, including epithelium, endothelium, placental cells and beta cells in Langerhans i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
