|
Rudolf Virchow Center
The Rudolf Virchow Center (''RVZ'') is the DFG Research Center for Integrative and Translational Bioimaging of the University of Würzburg. It was started in 2001 as one of three German ''Centers of Excellence'' funded by the German Research Foundation, DFG. Its founding chairman is Martin J. Lohse, a former coworker of Robert Lefkowitz at Duke University. Research The center derives its name from the pathologist Rudolf Virchow, who was a professor in Würzburg from 1849 to 1856 and was the first to postulate that diseases originated in dysfunctions of cells. Researchers at the Rudolf Virchow Center aim to trace diseases back to dysfunctions of proteins. These are called target proteins because they may serve as targets for diagnostic tools or for therapeutic drugs. Research is organized in four fields: (1) Protein structure and function (2) Proteins in cellular signaling (3) Nucleic acid Nucleic acids are biopolymers, macromolecules, essential to all known forms of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Würzburg
Würzburg (; Main-Franconian: ) is a city in the region of Franconia in the north of the German state of Bavaria. Würzburg is the administrative seat of the '' Regierungsbezirk'' Lower Franconia. It spans the banks of the Main River. Würzburg is situated approximately east-southeast of Frankfurt am Main and approximately west-northwest of Nuremberg (). The population (as of 2019) is approximately 130,000 residents. The administration of the ''Landkreis Würzburg'' ( district of Würzburg) is also located in the town. The regional dialect is East Franconian. History Early and medieval history A Bronze Age (Urnfield culture) refuge castle, the Celtic Segodunum,Koch, John T. (2020)CELTO-GERMANIC Later Prehistory and Post-Proto-Indo-European vocabulary in the North and West p. 131 and later a Roman fort, stood on the hill known as the Leistenberg, the site of the present Fortress Marienberg. The former Celtic territory was settled by the Alamanni in the 4th or 5t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Basic Research
Basic research, also called pure research or fundamental research, is a type of scientific research with the aim of improving scientific theory, theories for better understanding and prediction of natural or other phenomena. In contrast, applied research uses scientific theories to develop technology or techniques which can be used to intervene and ''alter'' natural or other phenomena. Though often driven simply by curiosity,"Curiosity creates cures: The value and impact of basic research , National Institute of General Medical Sciences, National Institutes of Health. basic research often fuels the technological innovations of applied science. The two aims are often practiced simultaneously in coordinated research and development. In addition to innovations, b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Science
Science is a systematic endeavor that Scientific method, builds and organizes knowledge in the form of Testability, testable explanations and predictions about the universe. Science may be as old as the human species, and some of the earliest archeological evidence for scientific reasoning is tens of thousands of years old. The earliest written records in the history of science come from Ancient Egypt and Mesopotamia in around 3000 to 1200 Common Era, BCE. Their contributions to mathematics, astronomy, and medicine entered and shaped Greek natural philosophy of classical antiquity, whereby formal attempts were made to provide explanations of events in the Universe, physical world based on natural causes. After the fall of the Western Roman Empire, knowledge of History of science in classical antiquity, Greek conceptions of the world deteriorated in Western Europe during the early centuries (400 to 1000 CE) of the Middle Ages, but was preserved in the Muslim world during the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biology
Biology is the scientific study of life. It is a natural science with a broad scope but has several unifying themes that tie it together as a single, coherent field. For instance, all organisms are made up of cells that process hereditary information encoded in genes, which can be transmitted to future generations. Another major theme is evolution, which explains the unity and diversity of life. Energy processing is also important to life as it allows organisms to move, grow, and reproduce. Finally, all organisms are able to regulate their own internal environments. Biologists are able to study life at multiple levels of organization, from the molecular biology of a cell to the anatomy and physiology of plants and animals, and evolution of populations.Based on definition from: Hence, there are multiple subdisciplines within biology, each defined by the nature of their research questions and the tools that they use. Like other scientists, biologists use t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medicine
Medicine is the science and Praxis (process), practice of caring for a patient, managing the diagnosis, prognosis, Preventive medicine, prevention, therapy, treatment, Palliative care, palliation of their injury or disease, and Health promotion, promoting their health. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention (medical), prevention and therapy, treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, medical genetics, genetics, and medical technology to diagnosis (medical), diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, splint (medicine), external splints and traction, medical devices, biologic medical product, biologics, and Radiation (medicine), ionizing radiation, amongst others. Medicine has been practiced since Prehistoric medicine, prehistoric times, and for most o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Martin J
Martin may refer to: Places * Martin City (other) * Martin County (other) * Martin Township (other) Antarctica * Martin Peninsula, Marie Byrd Land * Port Martin, Adelie Land * Point Martin, South Orkney Islands Australia * Martin, Western Australia * Martin Place, Sydney Caribbean * Martin, Saint-Jean-du-Sud, Haiti, a village in the Sud Department of Haiti Europe * Martin, Croatia, a village in Slavonia, Croatia * Martin, Slovakia, a city * Martín del Río, Aragón, Spain * Martin (Val Poschiavo), Switzerland England * Martin, Hampshire * Martin, Kent * Martin, East Lindsey, Lincolnshire, hamlet and former parish in East Lindsey district * Martin, North Kesteven, village and parish in Lincolnshire in North Kesteven district * Martin Hussingtree, Worcestershire * Martin Mere, a lake in Lancashire ** WWT Martin Mere, a wetland nature reserve that includes the lake and surrounding areas * Martin Mill, Kent North America Canada * Rural ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rudolf Virchow
Rudolf Ludwig Carl Virchow (; or ; 13 October 18215 September 1902) was a German physician, anthropologist, pathologist, prehistorian, biologist, writer, editor, and politician. He is known as "the father of modern pathology" and as the founder of social medicine, and to his colleagues, the "Pope of medicine". Virchow studied medicine at the Friedrich Wilhelm University under Johannes Peter Müller. While working at the Charité hospital, his investigation of the 1847–1848 typhus epidemic in Upper Silesia laid the foundation for public health in Germany, and paved his political and social careers. From it, he coined a well known aphorism: "Medicine is a social science, and politics is nothing else but medicine on a large scale". His participation in the Revolution of 1848 led to his expulsion from Charité the next year. He then published a newspaper ''Die Medizinische Reform'' (''The Medical Reform''). He took the first Chair of Pathological Anatomy at the University of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Deutsche Forschungsgemeinschaft
The German Research Foundation (german: Deutsche Forschungsgemeinschaft ; DFG ) is a German research funding organization, which functions as a self-governing institution for the promotion of science and research in the Federal Republic of Germany. In 2019, the DFG had a funding budget of €3.3 billion. Function The DFG supports research in science, engineering, and the humanities through a variety of grant programmes, research prizes, and by funding infrastructure. The self-governed organization is based in Bonn and financed by the German states and the federal government of Germany. As of 2017, the organization consists of approximately 100 research universities and other research institutions. The DFG endows various research prizes, including the Leibniz Prize. The Polish-German science award Copernicus is offered jointly with the Foundation for Polish Science. According to a 2017 article in ''The Guardian'', the DFG has announced it will publish its research in onl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Würzburg
The Julius Maximilian University of Würzburg (also referred to as the University of Würzburg, in German ''Julius-Maximilians-Universität Würzburg'') is a public research university in Würzburg, Germany. The University of Würzburg is one of the oldest institutions of higher learning in Germany, having been founded in 1402. The university initially had a brief run and was closed in 1415. It was reopened in 1582 on the initiative of Julius Echter von Mespelbrunn. Today, the university is named for Julius Echter von Mespelbrunn and Maximilian Joseph. The University of Würzburg is part of the U15 group of research-intensive German universities. The university is also a member of the Coimbra Group. Name Its official name is Julius-Maximilians-Universität Würzburg (or "Julius-Maximilian University of Würzburg") but it is commonly referred to as the University of Würzburg. This name is taken from Julius Echter von Mespelbrunn, Prince-Bishop of Würzburg, who reestablis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Robert Lefkowitz
Robert Joseph Lefkowitz (born April 15, 1943) is an American physician (internist and cardiologist) and biochemist. He is best known for his groundbreaking discoveries that reveal the inner workings of an important family G protein-coupled receptors, for which he was awarded the 2012 Nobel Prize for Chemistry with Brian Kobilka. He is currently an Investigator with the Howard Hughes Medical Institute as well as a James B. Duke Professor of Medicine and Professor of Biochemistry and Chemistry at Duke University. Early life Lefkowitz was born on April 15, 1943, in The Bronx, New York to Jewish parents Max and Rose Lefkowitz. Their families had emigrated to the United States from Poland in the late 19th century. After graduating from the Bronx High School of Science in 1959, he attended Columbia College from which he received a Bachelor of Arts in chemistry 1962. He graduated from Columbia University College of Physicians and Surgeons in 1966 with an M.D. Degree. After serving a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Duke University
Duke University is a private research university in Durham, North Carolina. Founded by Methodists and Quakers in the present-day city of Trinity in 1838, the school moved to Durham in 1892. In 1924, tobacco and electric power industrialist James Buchanan Duke established The Duke Endowment and the institution changed its name to honor his deceased father, Washington Duke. The campus spans over on three contiguous sub-campuses in Durham, and a marine lab in Beaufort. The West Campus—designed largely by architect Julian Abele, an African American architect who graduated first in his class at the University of Pennsylvania School of Design—incorporates Gothic architecture with the Duke Chapel at the campus' center and highest point of elevation, is adjacent to the Medical Center. East Campus, away, home to all first-years, contains Georgian-style architecture. The university administers two concurrent schools in Asia, Duke-NUS Medical School in Singapore (e ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein Structure
Protein structure is the molecular geometry, three-dimensional arrangement of atoms in an amino acid-chain molecule. Proteins are polymers specifically polypeptides formed from sequences of amino acids, the monomers of the polymer. A single amino acid monomer may also be called a ''residue'' indicating a repeating unit of a polymer. Proteins form by amino acids undergoing condensation reactions, in which the amino acids lose one water molecule per chemical reaction, reaction in order to attach to one another with a peptide bond. By convention, a chain under 30 amino acids is often identified as a peptide, rather than a protein. To be able to perform their biological function, proteins fold into one or more specific spatial conformations driven by a number of non-covalent interactions such as hydrogen bonding, ionic interactions, Van der Waals forces, and hydrophobic packing. To understand the functions of proteins at a molecular level, it is often necessary to determine their Pro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
