Rubottom Oxidation
The Rubottom oxidation is a useful, high-yielding chemical reaction between silyl enol ethers and peroxyacids to give the corresponding α-hydroxy carbonyl product.Kürti, pp. 388–389.Myers, A.G. Chemistry 215: Oxidation
. chem.harvard.eduLi, pp. 478–479.Chen, B. C.; Zhou, P.; Davis, F. A.; Ciganek, E. (2003) “α-Hydroxylation of Enolates and Silyl Enol Ethers." in ''Organic Reactions''; Ed. Overman, L.E. Wiley, Chapter 1, pp. 1–355, . The mechanism of the reaction was proposed in its original disclosure by A.G. Brook with further evidence later supplied by George M. Rubottom. After a
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Chemical Reaction
A chemical reaction is a process that leads to the chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the positions of electrons in the forming and breaking of chemical bonds between atoms, with no change to the nuclei (no