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Roborat
A remotely guided rat, popularly called a ratbot or robo-rat, is a rat with electrodes implanted in the medial forebrain bundle (MFB) and sensorimotor cortex of its brain. They were developed in 2002 by Sanjiv Talwar and John Chapin at the State University of New York Downstate Medical Center. The rats wear a small electronics backpack containing a radio receiver and electrical stimulator. The rat receives remote stimulation in the sensorimotor cortex via its backpack that causes the rat to feel a sensation in its left or right whiskers, and stimulation in the MFB that is interpreted as a reward or pleasure. After a period of training and conditioning using MFB stimulation as a reward, the rats can be remotely directed to move left, right, and forward in response to whisker stimulation signals. It is possible to roughly guide the animal along an obstacle course, jumping small gaps and scaling obstacles. Ethics Concerns have been raised by animal rights groups about the use of ani ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medial Forebrain Bundle
The medial forebrain bundle (MFB) is a neural pathway containing fibers from the basal olfactory regions, the periamygdaloid region and the septal nuclei, as well as fibers from brainstem regions, including the ventral tegmental area and nigrostriatal pathway. Anatomy The MFB passes through the lateral hypothalamus and the basal forebrain in a rostral-caudal direction. The MFB has its main projections to these regions of Brodmann areas (BA) 8, 9, 10, 11, 11m. The superior frontal region of MFB projects to BA 8, 9, 10; the rostral middle frontal projects to dorsolateral prefrontal cortex (BA 9, 10); lateral orbitofrontal of MFB shows its projections to nucleus accumbens septi (NAC) and ventral striatum as subcortical reward associated structures. It contains both ascending and descending fibers. The mesolimbic pathway, which is a collection of dopaminergic neurons that projects from the ventral tegmental area to the nucleus accumbens, is a component pathway of the MFB. The MFB i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sensorimotor Cortex
The motor cortex is the region of the cerebral cortex involved in the planning, motor control, control, and execution of voluntary movements. The motor cortex is an area of the frontal lobe located in the posterior precentral gyrus immediately anterior to the central sulcus. Components The motor cortex can be divided into three areas: 1. The primary motor cortex is the main contributor to generating neural impulses that pass down to the spinal cord and control the execution of movement. However, some of the other motor areas in the brain also play a role in this function. It is located on the anterior paracentral lobule on the medial surface. 2. The premotor cortex is responsible for some aspects of motor control, possibly including the preparation for movement, the sensory guidance of movement, the spatial guidance of reaching, or the direct control of some movements with an emphasis on control of proximal and trunk muscles of the body. Located anterior to the primary mo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
SUNY Downstate Medical Center
SUNY Downstate Health Sciences University is a public medical school and hospital in Brooklyn, New York. It is the southernmost member of the State University of New York (SUNY) system and the only academic medical center for health education, research, and patient care serving Brooklyn's 2.5 million residents. It is the only state-run hospital in New York City. As of fall 2018, it had a total student body of 1,846 and approximately 8,000 faculty and staff. Downstate Health Sciences University comprises a College of Medicine, Colleges of Nursing, School of Graduate Studies, School of Health Professions, and School of Public Health, and University Hospital of Brooklyn. It also includes a major research complex and biotechnology facilities. History In 2010 SUNY Downstate celebrated its sesquicentennial, commemorating the year that the Long Island College Hospital (as it was then known) first opened its doors to students. Yet Downstate traces its roots back even further (to 185 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Radio Receiver
In radio communications, a radio receiver, also known as a receiver, a wireless, or simply a radio, is an electronic device that receives radio waves and converts the information carried by them to a usable form. It is used with an antenna. The antenna intercepts radio waves (electromagnetic waves of radio frequency) and converts them to tiny alternating currents which are applied to the receiver, and the receiver extracts the desired information. The receiver uses electronic filters to separate the desired radio frequency signal from all the other signals picked up by the antenna, an electronic amplifier to increase the power of the signal for further processing, and finally recovers the desired information through demodulation. Radio receivers are essential components of all systems based on radio technology. The information produced by the receiver may be in the form of sound, video (television), or digital data. A radio receiver may be a separate piece of electronic equ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vibrissae
Whiskers, also known as vibrissae (; vibrissa; ) are a type of stiff, functional hair used by most therian mammals to sense their environment. These hairs are finely specialised for this purpose, whereas other types of hair are coarser as tactile sensors. Although whiskers are specifically those found around the face, vibrissae are known to grow in clusters at various places around the body. Most mammals have them, including all non-human primates and especially nocturnal mammals. Monotremes, however, lack them. Whiskers are sensitive tactile hairs that aid navigation, locomotion, exploration, hunting, social touch and perform other functions. This article is primarily about the specialised sensing hairs of mammals, but some birds, fish, insects, crustaceans and other arthropods are known to have similar structures also used to sense the environment. Etymology Vibrissae (from Latin 'to vibrate') from the characteristic motion seen in a small rodent that is otherwise sitt ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Reward System
The reward system (the mesocorticolimbic circuit) is a group of neural structures responsible for incentive salience (i.e., "wanting"; desire or craving for a reward and motivation), associative learning (primarily positive reinforcement and classical conditioning), and positively-valenced emotions, particularly ones involving pleasure as a core component (e.g., joy, euphoria and ecstasy). Reward is the attractive and motivational property of a stimulus that induces appetitive behavior, also known as approach behavior, and consummatory behavior. A rewarding stimulus has been described as "any stimulus, object, event, activity, or situation that has the potential to make us approach and consume it is by definition a reward". In operant conditioning, rewarding stimuli function as positive reinforcers; however, the converse statement also holds true: positive reinforcers are rewarding. The reward system motivates animals to approach stimuli or engage in behaviour that increase ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Physical Exercise
Exercise or workout is physical activity that enhances or maintains fitness and overall health. It is performed for various reasons, including weight loss or maintenance, to aid growth and improve strength, develop muscles and the cardiovascular system, prevent injuries, hone athletic skills, improve health, or simply for enjoyment. Many people choose to exercise outdoors where they can congregate in groups, socialize, and improve well-being as well as mental health. In terms of health benefits, usually, 150 minutes of moderate-intensity exercise per week is recommended for reducing the risk of health problems. At the same time, even doing a small amount of exercise is healthier than doing none. Only doing an hour and a quarter (11 minutes/day) of exercise could reduce the risk of early death, cardiovascular disease, stroke, and cancer. Classification Physical exercises are generally grouped into three types, depending on the overall effect they have on the huma ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dr Hadwen Trust
Animal Free Research UK (AFRUK), formerly the Dr Hadwen Trust, is a UK medical research charity that funds and promotes non-animal techniques to replace animal experiments.Pain Experts Say Greater Focus On High-Tech Non-Animal Research Could Help Thousands Of Patients 15 August 2008 Established in 1970, the work undertaken by Animal Free Research UK develops reliable science whilst avoiding animal testing. History Animal Free Research UK was established as the Dr Hadwen Trust for Humane Research in 1970 (registered charity number 261096). It was formed ...[...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Operant Conditioning
Operant conditioning, also called instrumental conditioning, is a learning process in which voluntary behaviors are modified by association with the addition (or removal) of reward or aversive stimuli. The frequency or duration of the behavior may increase through reinforcement or decrease through punishment or Extinction (psychology), extinction. Origins Operant conditioning originated with Edward Thorndike, whose law of effect theorised that behaviors arise as a result of consequences as satisfying or discomforting. In the 20th century, operant conditioning was studied by Behaviorism, behavioral psychologists, who believed that much of mind and behaviour is explained through environmental conditioning. Reinforcements are environmental stimuli that increase behaviors, whereas punishments are stimuli that decrease behaviors. Both kinds of stimuli can be further categorised into positive and negative stimuli, which respectively involve the addition or removal of environmental stim ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Institute Of Health
The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research. It was founded in 1887 and is part of the United States Department of Health and Human Services (HHS). Many NIH facilities are located in Bethesda, Maryland, and other nearby suburbs of the Washington metropolitan area, with other primary facilities in the Research Triangle Park in North Carolina and smaller satellite facilities located around the United States. The NIH conducts its scientific research through the NIH Intramural Research Program (IRP) and provides significant biomedical research funding to non-NIH research facilities through its Extramural Research Program. , the IRP had 1,200 principal investigators and more than 4,000 postdoctoral fellows in basic, translational, and clinical research, being the largest biomedical research institution in the world, while, as of 2003, the extramural arm provided 28% of biomed ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brainwashing
Brainwashing is the controversial idea that the human mind can be altered or controlled against a person's will by manipulative psychological techniques. Brainwashing is said to reduce its subject's ability to think critically or independently, to allow the introduction of new, unwanted thoughts and ideas into their minds, as well as to change their attitudes, values, and beliefs. The term "brainwashing" was first used in English by Edward Hunter in 1950 to describe how the Chinese government appeared to make people cooperate with them during the Korean War. Research into the concept also looked at Nazi Germany and present-day North Korea, at some criminal cases in the United States, and at the actions of human traffickers. Scientific and legal debate followed, as well as media attention, about the possibility of brainwashing being a factor when lysergic acid diethylamide (LSD) was used, or in the induction of people into groups which are considered to be cults. Brainwashing ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
José Manuel Rodríguez Delgado
José Manuel Rodríguez Delgado (August 8, 1915 – September 15, 2011) was a Spanish professor of neurophysiology at Yale University, famed for his research on mind control through electrical stimulation of the brain.Horgan, J. (2017). Tribute to Jose Delgado, legendary and slightly scary pioneer of mind control. Retrieved from https://blogs.scientificamerican.com/cross-check/tribute-to-jose-delgado-legendary-and-slightly-scary-pioneer-of-mind-control/ Biography Rodríguez Delgado was born in Ronda, in the province of Málaga, Spain in 1915. He received a Doctor of Medicine degree from the University of Madrid just before the outbreak of the Spanish Civil War. During the Spanish Civil War he joined the Republican side and served as a medical corpsman while he was a medical student. Rodríguez Delgado was held in a concentration camp for five months after the war ended. After serving in the camp, he had to repeat his M.D. degree, and then gained a PhD at the Ramón y Caja ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
